Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Stuart Kellie"'
Autor:
Richa K Dave, Marcel E Dinger, Megan Andrew, Marjan Askarian-Amiri, David A Hume, Stuart Kellie
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e68306 (2013)
PTPRJ/CD148 is a tyrosine phosphatase that has tumour suppressor-like activity. Quantitative PCR of various cells and tissues revealed that it is preferentially expressed in macrophage-enriched tissues. Within lymphoid tissues immunohistochemistry re
Externí odkaz:
https://doaj.org/article/55948b746ef44323a41af07ca8017e89
Autor:
Chanel E Smart, Marjan E Askarian Amiri, Ania Wronski, Marcel E Dinger, Joanna Crawford, Dmitry A Ovchinnikov, Ana Cristina Vargas, Lynne Reid, Peter T Simpson, Sarah Song, Christiane Wiesner, Juliet D French, Richa K Dave, Leonard da Silva, Amy Purdon, Megan Andrew, John S Mattick, Sunil R Lakhani, Melissa A Brown, Stuart Kellie
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40742 (2012)
The protein tyrosine phosphatase receptor J, PTPRJ, is a tumor suppressor gene that has been implicated in a range of cancers, including breast cancer, yet little is known about its role in normal breast physiology or in mammary gland tumorigenesis.
Externí odkaz:
https://doaj.org/article/d5eaa5f72a81446caa82d85295dc8909
Autor:
Wendy J van Zuylen, Valerie Garceau, Adi Idris, Kate Schroder, Katharine M Irvine, Jane E Lattin, Dmitry A Ovchinnikov, Andrew C Perkins, Andrew D Cook, John A Hamilton, Paul J Hertzog, Katryn J Stacey, Stuart Kellie, David A Hume, Matthew J Sweet
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e15723 (2011)
BackgroundThe ten mouse and six human members of the Schlafen (Slfn) gene family all contain an AAA domain. Little is known of their function, but previous studies suggest roles in immune cell development. In this report, we assessed Slfn regulation
Externí odkaz:
https://doaj.org/article/0e772b52cc8148969f6d70d48c2a29ad
Publikováno v:
Fish & Shellfish Immunology. 113:42-50
Two IgM heavy (H) chain sub-isotypes (80 and 40 kDa) and two light (L) chain variants (25 and 30 kDa) were detected in the serum of giant grouper (Epinephelus lanceolatus), purified by ammonium sulphate precipitation followed by protein A affinity ch
Publikováno v:
Fishshellfish immunology. 91
The inflammatory response of fish to LPS is subdued, attributed to absence of TLR4, a key pro-inflammatory receptor for LPS in mammals. Nevertheless, LPS is processed in fish in a T-independent manner and is a protective antigen in fish vaccines, yet
Publikováno v:
Journal of Leukocyte Biology. 100:27-45
Toll/IL-1R domain-containing adaptor-inducing IFN-β (TRIF)-dependent signaling is required for TLR-mediated production of type-I IFN and several other proinflammatory mediators. Various pathogens target the signaling molecules and transcriptional re
The inflammatory response of fish to LPS is subdued, attributed to absence of TLR4, a key pro-inflammatory receptor for LPS in mammals. Nevertheless, LPS is processed in fish in a T-independent manner and is a protective antigen in fish vaccines, yet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::192d37a72b2938ea223dc4b57ed9c4ab
Autor:
Stuart Kellie, Z. Al-Mansour
The immune system is our primary defense mechanism against invading pathogenic organisms and has two arms: the innate immune system and the acquired (adaptive) immune system. Classically, the innate immune system reacts uniformly and nonselectively t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25a4977a65d04eacf19333509bc7f9be
https://doi.org/10.1016/b978-0-323-39981-4.00004-x
https://doi.org/10.1016/b978-0-323-39981-4.00004-x
Autor:
Kate Schroder, Gautier Robin, Justine M. Hill, Parimala R. Vajjhala, Stuart Kellie, Jennifer L. Martin, Bostjan Kobe, Kai-En Chen, Linda H.L. Lua, Matthew J. Sweet, Tom T. Caradoc-Davies, Ayanthi A. Richards
Publikováno v:
Acta Crystallographica Section D Biological Crystallography. 69:774-784
The caspase recruitment domain (CARD) is present in death-domain superfamily proteins involved in inflammation and apoptosis. BinCARD is named for its ability to interact with Bcl10 and inhibit downstream signalling. Human BinCARD is expressed as two
Publikováno v:
Molecular immunology. 83
Fish represent the most diverse and abundant extant vertebrate infraclass. They are also one of the earliest divergent phyla with adaptive immunity based on antigen recognition by MHC and immunoglobulin. The aquaculture industry, which currently prov