Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Stuart J. Frank"'
Autor:
Maïté Verreault, Irma Segoviano Vilchis, Shai Rosenberg, Nolwenn Lemaire, Charlotte Schmitt, Jérémy Guehennec, Louis Royer‐Perron, Jean‐Léon Thomas, TuKiet T. Lam, Florent Dingli, Damarys Loew, François Ducray, Sophie Paris, Catherine Carpentier, Yannick Marie, Florence Laigle‐Donadey, Audrey Rousseau, Natascha Pigat, Florence Boutillon, Franck Bielle, Karima Mokhtari, Stuart J. Frank, Aurélien deReyniès, Khê Hoang‐Xuan, Marc Sanson, Vincent Goffin, Ahmed Idbaih
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 7, Pp n/a-n/a (2022)
Abstract Objective New therapeutic approaches are needed to improve the prognosis of glioblastoma (GBM) patients. Methods With the objective of identifying alternative oncogenic mechanisms to abnormally activated epidermal growth factor receptor (EGF
Externí odkaz:
https://doaj.org/article/eda0001ce8334a88897701a1bbcf3626
Autor:
Ravi Sonkar, Ryan Berry, Mary N. Latimer, Sumanth D. Prabhu, Martin E. Young, Stuart J. Frank
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Circadian clocks regulate numerous biological processes, at whole body, organ, and cellular levels. This includes both hormone secretion and target tissue sensitivity. Although growth hormone (GH) secretion is time-of-day-dependent (increased pulse a
Externí odkaz:
https://doaj.org/article/1e631f784c0b42b58c6443225a64d935
Autor:
Ashiya Buckels, Yue Zhang, Jing Jiang, Mohammad Athar, Farrukh Afaq, Lalita Shevde-Samant, Stuart J. Frank
Publikováno v:
Biochemistry and Biophysics Reports, Vol 21, Iss , Pp - (2020)
Melanoma is the most aggressive skin cancer. Its aggressiveness is most commonly attributed to ERK pathway mutations leading to constitutive signaling. Though initial tumor regression results from targeting this pathway, resistance often emerges. Int
Externí odkaz:
https://doaj.org/article/76bb31cc99b54a1a8d7e79f7fcd0974a
Autor:
Shereen Ezzat, Stuart J. Frank, Katsuhiko Yoshimoto, Toshiaki Sano, Shozo Yamada, Kimberly Loesch, Megan L. Ward, Jing Jiang, Rebecca DiGiovanni, Sylvia L. Asa
Pituitary tumors are a diverse group of neoplasms that are classified based on clinical manifestations, hormone excess, and histomorphologic features. Those that cause growth hormone (GH) excess and acromegaly are subdivided into morphologic variants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39cfdcc00029ae7535868531889b082f
https://doi.org/10.1158/0008-5472.c.6495534.v1
https://doi.org/10.1158/0008-5472.c.6495534.v1
Autor:
Shereen Ezzat, Stuart J. Frank, Katsuhiko Yoshimoto, Toshiaki Sano, Shozo Yamada, Kimberly Loesch, Megan L. Ward, Jing Jiang, Rebecca DiGiovanni, Sylvia L. Asa
Supplementary Table 1 from A Growth Hormone Receptor Mutation Impairs Growth Hormone Autofeedback Signaling in Pituitary Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bdf0c96861791920f099668f05b3400
https://doi.org/10.1158/0008-5472.22367388
https://doi.org/10.1158/0008-5472.22367388
Autor:
Takahiro Sawada, Daiki Arai, Xuefeng Jing, Masayasu Miyajima, Stuart J Frank, Kazushige Sakaguchi
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180785 (2017)
We previously reported that EphA4, a member of the Eph family of receptor tyrosine kinases, is an important modulator of growth hormone (GH) signaling, leading to augmented synthesis of insulin-like growth factor 1 (IGF1) for postnatal body growth. I
Externí odkaz:
https://doaj.org/article/2731fef9a35c4fc89281445d2e66c4c3
Autor:
Irma Segoviano Vilchis, Maite Verreault, Nolwenn Lemaire, Natasha Pigat, Florence Boutillon, Franck Bielle, Karima Mokhtari, Stuart J. Frank, Khe Hoang-Xuan, Marc Sanson, Jean-Yves Delattre, Vincent Goffin, Ahmed Idbaih
Publikováno v:
WFNOS 2022 Abstract Book.
Autor:
Ronadip R. Banerjee, Tara Spence, Raj Pandian, Bob Argiropoulos, Andrew N. Hoofnagle, Stuart J. Frank, Julien Marcadier
Publikováno v:
Journal of the Endocrine Society
Circulating plasma vitamin D metabolites are highly bound to vitamin D-binding protein (DBP), also known as group-specific component or Gc-globulin. DBP, encoded by the GC gene, is a member of the albumin family of globular serum transport proteins.
Autor:
Christine Des Rosiers, Sobuj Mia, Martin E. Young, Lamario Williams, Mary N. Latimer, Isabelle Frayne Robillard, Stuart J. Frank, Ravi Sonkar, Abhinav Diwan
Publikováno v:
The FASEB Journal
An intrinsic property of the heart is an ability to rapidly and coordinately adjust flux through metabolic pathways in response to physiologic stimuli (termed metabolic flexibility). Cardiac metabolism also fluctuates across the 24‐hours day, in as