Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Stuart J. Conway"'
Autor:
Glen Brodie, Stuart J. Conway
Publikováno v:
ACS Central Science, Vol 9, Iss 12, Pp 2179-2182 (2023)
Externí odkaz:
https://doaj.org/article/947b5facf7fb452a8689f65ebbd483d3
Autor:
Çağla Tosun, Antoine L. D. Wallabregue, Maxim Mallerman, Sarah E. Phillips, Claire M. Edwards, Stuart J. Conway, Ester M. Hammond
Publikováno v:
JACS Au, Vol 3, Iss 11, Pp 3237-3246 (2023)
Externí odkaz:
https://doaj.org/article/f6bbe8301e6b41e192559873637f1252
Autor:
Barney A. Geddes, Ponraj Paramasivan, Amelie Joffrin, Amber L. Thompson, Kirsten Christensen, Beatriz Jorrin, Paul Brett, Stuart J. Conway, Giles E. D. Oldroyd, Philip S. Poole
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
The root microbiota is critical for promoting crop yield. Here, the authors create a synthetic pathway for the production of the rhizopine scyllo-inosamine in Medicago truncatula and barley, and show its perception by rhizosphere bacteria for targete
Externí odkaz:
https://doaj.org/article/76ec5e3ff5b047cb9e0a123a27df0571
Autor:
Elizabeth Bowler, Anna Skwarska, Joseph D. Wilson, Shaliny Ramachandran, Hannah Bolland, Alistair Easton, Christian Ostheimer, Ming-Shih Hwang, Katarzyna B. Leszczynska, Stuart J. Conway, Ester M. Hammond
Publikováno v:
iScience, Vol 23, Iss 11, Pp 101668- (2020)
Summary: Inhibition of the ATR kinase has emerged as a therapeutically attractive means to target cancer since the development of potent inhibitors, which are now in clinical testing. We investigated a potential link between ATR inhibition and the au
Externí odkaz:
https://doaj.org/article/9101f532972247d3b9744910af5a4602
Autor:
Gabriele Bassi, Nicholas Favalli, Miriam Vuk, Marco Catalano, Adriano Martinelli, Anika Trenner, Antonio Porro, Su Yang, Chuin Lean Tham, Mustafa Moroglu, Wyatt W. Yue, Stuart J. Conway, Peter K. Vogt, Alessandro A. Sartori, Jörg Scheuermann, Dario Neri
Publikováno v:
Advanced Science, Vol 7, Iss 22, Pp n/a-n/a (2020)
Abstract A versatile and Lipinski‐compliant DNA‐encoded library (DEL), comprising 366 600 glutamic acid derivatives coupled to oligonucleotides serving as amplifiable identification barcodes is designed, constructed, and characterized. The GB‐D
Externí odkaz:
https://doaj.org/article/6523af672d2b411ba7e7080f84e45492
Publikováno v:
ACS Bio & Med Chem Au, Vol 1, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/a4d7897131d94d82858e4a9cf4be2080
Autor:
Noah R. Flynn, Michael D. Ward, Mary A. Schleiff, Corentine M. C. Laurin, Rohit Farmer, Stuart J. Conway, Gunnar Boysen, S. Joshua Swamidass, Grover P. Miller
Publikováno v:
Metabolites, Vol 11, Iss 6, p 390 (2021)
The 3,5-dimethylisoxazole motif has become a useful and popular acetyl-lysine mimic employed in isoxazole-containing bromodomain and extra-terminal (BET) inhibitors but may introduce the potential for bioactivations into toxic reactive metabolites. A
Externí odkaz:
https://doaj.org/article/fe2c0e1578ea4615936896f4cf2d1320
Autor:
Liam J. O’Connor, Ishna N. Mistry, Sarah L. Collins, Lisa K. Folkes, Graham Brown, Stuart J. Conway, Ester M. Hammond
Publikováno v:
ACS Central Science, Vol 3, Iss 1, Pp 20-30 (2016)
Externí odkaz:
https://doaj.org/article/1f5dd5db05b144d7a17a6b55a3c87d4b
Autor:
Angelina R. Sekirnik, Jessica K. Reynolds, Larissa See, Joseph P. Bluck, Amy R. Scorah, Cynthia Tallant, Bernadette Lee, Katarzyna B. Leszczynska, Rachel L. Grimley, R. Ian Storer, Marta Malattia, Sara Crespillo, Sofia Caria, Stephanie Duclos, Ester M. Hammond, Stefan Knapp, Garrett M. Morris, Fernanda Duarte, Philip C. Biggin, Stuart J. Conway
Publikováno v:
ACS Chemical Biology. 17:2753-2768
TRIM33 is a member of the tripartite motif (TRIM) family of proteins, some of which possess E3 ligase activity and are involved in the ubiquitin-dependent degradation of proteins. Four of the TRIM family proteins, TRIM24 (TIF1α), TRIM28 (TIF1β), TR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e2aeb12794430ed27bbc1291d39218
https://doi.org/10.1021/acschembio.2c00266
https://doi.org/10.1021/acschembio.2c00266
Autor:
Courtney C. Aldrich, Félix Calderón, Stuart J. Conway, Chuan He, Jacob M. Hooker, Donna M. Huryn, Craig W. Lindsley, Dennis C. Liotta, Christa E. Müller
Publikováno v:
ACS Chemical Neuroscience. 13:2668-2673
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f0009e408e7311adde6fc28739ada5
https://doi.org/10.1021/acschemneuro.2c00501
https://doi.org/10.1021/acschemneuro.2c00501