Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Stuart J. Andrews"'
Autor:
Filemon S. Dela Cruz, Daniel Diolaiti, Andrew T. Turk, Allison R. Rainey, Alberto Ambesi-Impiombato, Stuart J. Andrews, Mahesh M. Mansukhani, Peter L. Nagy, Mariano J. Alvarez, Andrea Califano, Farhad Forouhar, Beata Modzelewski, Chelsey M. Mitchell, Darrell J. Yamashiro, Lianna J. Marks, Julia L. Glade Bender, Andrew L. Kung
Publikováno v:
Genome Medicine, Vol 8, Iss 1, Pp 1-17 (2016)
Abstract Background Precision medicine approaches are ideally suited for rare tumors where comprehensive characterization may have diagnostic, prognostic, and therapeutic value. We describe the clinical case and molecular characterization of an adole
Externí odkaz:
https://doaj.org/article/d3e2f19cbddb43b485ebb884633c5a3a
Autor:
Jin Liu, Fatou Amar, Carlo Corona, Raphaella W. L. So, Stuart J. Andrews, Peter L. Nagy, Michael L. Shelanski, Lloyd A. Greene
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Activating transcription factor 4 (ATF4) plays important physiologic roles in the brain including regulation of learning and memory as well as neuronal survival and death. Yet, outside of translational regulation by the eIF2α-dependent stress respon
Externí odkaz:
https://doaj.org/article/1aba7b19431a41e48f667dd4aaa19b05
Autor:
Spiro P. Pantazatos, Stuart J. Andrews, Jane Dunning-Broadbent, Jiuhong Pang, Yung-yu Huang, Victoria Arango, Peter L. Nagy, J. John Mann
Publikováno v:
Neurobiology of Disease, Vol 79, Iss , Pp 123-134 (2015)
Low brain expression of the spermidine/spermine N-1 acetyltransferase (SAT1) gene, the rate-limiting enzyme involved in catabolism of polyamines that mediate the polyamine stress response (PSR), has been reported in depressed suicides. However, it is
Externí odkaz:
https://doaj.org/article/58c736dc47444775a30109872cdf9a5a
Autor:
Mariano J. Alvarez, Filemon S. Dela Cruz, Andrew L. Kung, Lianna J. Marks, Peter L. Nagy, Darrell J. Yamashiro, Stuart J. Andrews, Andrea Califano, Mahesh M. Mansukhani, Julia L. Glade Bender, Allison R. Rainey, Alberto Ambesi-Impiombato, Daniel Diolaiti, Farhad Forouhar, Andrew T. Turk, Chelsey M. Mitchell, Beata Modzelewski
Publikováno v:
Genome Medicine, Vol 8, Iss 1, Pp 1-17 (2016)
Genome Medicine
Genome Medicine
Background Precision medicine approaches are ideally suited for rare tumors where comprehensive characterization may have diagnostic, prognostic, and therapeutic value. We describe the clinical case and molecular characterization of an adolescent wit
Autor:
Michael L. Shelanski, Fatou Amar, Peter L. Nagy, Raphaella W. L. So, Lloyd A. Greene, Carlo Corona, Jin Liu, Stuart J. Andrews
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Activating transcription factor 4 (ATF4) plays important physiologic roles in the brain including regulation of learning and memory as well as neuronal survival and death. Yet, outside of translational regulation by the eIF2α-dependent stress respon
Autor:
Jin, Liu, Fatou, Amar, Carlo, Corona, Raphaella W L, So, Stuart J, Andrews, Peter L, Nagy, Michael L, Shelanski, Lloyd A, Greene
Publikováno v:
Frontiers in Molecular Neuroscience
Activating transcription factor 4 (ATF4) plays important physiologic roles in the brain including regulation of learning and memory as well as neuronal survival and death. Yet, outside of translational regulation by the eIF2α-dependent stress respon
Autor:
Jane Dunning-Broadbent, Jiuhong Pang, Yung-yu Huang, J. John Mann, Peter L. Nagy, Victoria Arango, Spiro P. Pantazatos, Stuart J. Andrews
Publikováno v:
Neurobiology of Disease, Vol 79, Iss, Pp 123-134 (2015)
Low brain expression of the spermidine/spermine N-1 acetyltransferase (SAT1) gene, the rate-limiting enzyme involved in catabolism of polyamines that mediate the polyamine stress response (PSR), has been reported in depressed suicides. However, it is
Autor:
Jiyong Wang, Xavier Tadeo, James J. Moresco, Songtao Jia, Stuart J. Andrews, Peter L. Nagy, John R. Yates, Haitong Hou
Publikováno v:
Nucleic Acids Research
Heterochromatin preferentially forms at repetitive DNA elements through RNAi-mediated targeting of histone-modifying enzymes. It was proposed that splicing factors interact with the RNAi machinery or regulate the splicing of repeat transcripts to dir
Autor:
Helen Remotti, Andrew T. Turk, Andrew L. Kung, Danielle Pendrick, Hanina Hibshoosh, Stuart J. Andrews, Wendy K. Chung, Filemon S. Dela Cruz, Daniel Diolaiti, Peter L. Nagy, Jennifer A. Oberg, Rebecca J. Zylber, Julia L. Glade Bender, Anthony N. Sireci, Carrie Koval, Jiuhong Pang, Maria Luisa Sulis, Darrell J. Yamashiro, Mahesh M. Mansukhani, Susan J. Hsiao, James Garvin, Stephen G. Emerson
Publikováno v:
Genome Medicine
Background Molecular characterization has the potential to advance the management of pediatric cancer and high-risk hematologic disease. The clinical integration of genome sequencing into standard clinical practice has been limited and the potential
Autor:
Liang Tong, Huijie Chen, Chun-Min Shan, Jia-Xing Yue, Peter L. Nagy, James J. Moresco, John R. Yates, Jiyong Wang, Stuart J. Andrews, Songtao Jia, Ke Xu
Publikováno v:
eLife
eLife, Vol 5 (2016)
eLife, Vol 5 (2016)
Histone lysine-to-methionine (K-to-M) mutations are associated with multiple cancers, and they function in a dominant fashion to block the methylation of corresponding lysines on wild type histones. However, their mechanisms of function are controver