Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Stuart J McLarnon"'
Publikováno v:
Journal of Biological Chemistry. 282:37678-37693
Cross-talk between intracellular calcium ([Ca(2+)](i)) signaling and cAMP defines the specificity of stimulus-response coupling in a variety of cells. Previous studies showed that protein kinase A (PKA) potentiates and phosphorylates the plasma membr
Autor:
Stuart J. McLarnon, Jian-kang Jiang, Kenneth A. Jacobson, Craig J. Thomas, Jianxin Hu, Stefano Mora, Allen M. Spiegel
Publikováno v:
Journal of Biological Chemistry. 280:5113-5120
Of 12 naturally occurring, activating mutations in the seven-transmembrane (7TM) domain of the human Ca2+ receptor (CaR) identified previously in subjects with autosomal dominant hypocalcemia (ADH), five appear at the junction of TM helices 6 and 7 b
Autor:
Robert A. Fenton, C. J. Ferguson, Mathieu Delannoy, Craig P. Smith, Alan G. Cox, Daniela Riccardi, Raymond Mcmahon, Mark Wareing, Stuart J McLarnon, Nick Ashton, Laura M. Garrick, R. Green
Publikováno v:
Kidney International. 64(5):1755-1764
Iron handling and gene expression of the divalent metal transporter, DMT1, in the kidney of the anemic Belgrade (b) rat.BackgroundWe have previously shown that the rat kidney reabsorbs metabolically significant amounts of iron and that it expresses t
Autor:
Donald T. Ward, Malcolm N. Jones, Darren Holden, Daniela Riccardi, Stuart J McLarnon, Austin C. Elliott
Publikováno v:
Biochemical and Biophysical Research Communications. 297:71-77
The aminoglycoside antibiotic (AGA) neomycin is a known agonist of the extracellular calcium-sensing receptor (CaR). To test whether other AGA drugs stimulate the CaR, we studied the relative effects of four AGAs on intracellular Ca(2+) concentration
Autor:
Daniela Riccardi, Stuart J McLarnon
Publikováno v:
European Journal of Pharmacology. 447:271-278
Extracellular Ca(2+) concentration [Ca(2+)](o) is vital for a number of processes varying from blood clotting to regulation membrane permeability and excitability. For this reason [Ca(2+)](o) is under strict control of a complex homeostatic system th
Publikováno v:
Journal of the American Society of Nephrology : JASN. 13(6)
Aminoglycoside antibiotics (AGAs) are nephrotoxic, with most of the damage confined to the proximal tubule, but the mechanism for cellular toxicity is not clear. It has been previously shown that the extracellular-calcium sensing receptor (CaR) is ex