Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Stuart J, Ings"'
Autor:
Stephen Mackinnon, Maria del Mar Cuadrado, Alejandro Madrigal, Kirsty Thomson, Jude Dorman, Hanna Renshaw, Stuart J. Ings, Ben Carpenter, Michael J. Watts, Rachael Hough, Ronjon Chakraverty, Emma C. Morris, Mark W. Lowdell, Panagiotis D. Kottaridis, Chloe Anthias, Nishil Patel, Karl S. Peggs, Richard Szydlo
Publikováno v:
Haematologica
Poor graft function is a serious complication following allogeneic hematopoietic stem cell transplantation. Infusion of CD34+-selected stem cells without pre-conditioning has been used to correct poor graft function, but predictors of recovery are un
Publikováno v:
Bone marrow transplantation. 53(6)
Autor:
Karl S. Peggs, Eleni Tholouli, Persis Amrolia, Laura Clifton-Hadley, Catherine Irving, Barry Flutter, Fernanda Castro, Stuart J. Ings, Kim Champion, Joan Casanovas-Company, Aleks Guvenel, Angela Collura, Rachael Wilding, Bilyana Popova, Timothy Pulham, Kimberly Gilmour, Thomas Taylor, Oliver Schofield, Sarah J. Albon, Rebecca Wallace, Andre Lopes, Wendy Ogden, Meera Subramaniyam, Rachel Richardson, Stuart Adams, Robert Herlihy, Stephen Mackinnon, Gulrukh Ahsan, Maria Farrell, Sara Ghorashian
Publikováno v:
Blood. 134:1995-1995
Karl S Peggs and Sarah J Albon contributed equally to the work and are joint first author Introduction Alemtuzumab reduces the incidence of GVHD after unrelated donor stem cell transplant (MUD SCT) but delays immune reconstitution resulting in high m
Autor:
Kwee Yong, Konstantina Kallinikou, Michael J. Watts, Fernando Anjos-Afonso, Michael P. Blundell, David C. Linch, Stuart J. Ings, Adrian J. Thrasher, Dominique Bonnet
Publikováno v:
British Journal of Haematology. 158:778-787
In vitro exposure of haematopoietic stem and progenitor cells (HSPC) to cytokines in expansion or gene therapy protocols reduces homing and engraftment in vivo. We have previously reported that this is related in part to altered tissue specificity of
Autor:
Kirsty Thomson, Chloe Anthias, Emma C. Morris, J. Alejandro Madrigal, Michael J. Watts, Panagiotis D. Kottaridis, Ronjon Chakraverty, Mark W. Lowdell, Rachael Hough, Stuart J. Ings, Ben Carpenter, Maria del Mar Cuadrado, Karl S. Peggs, Richard Szydlo
Publikováno v:
Blood. 132:204-204
Introduction: Graft failure (GF) is an infrequent but serious complication of following matched related or unrelated donor peripheral blood stem cell transplantation. Although infusion of CD34+-selected stem cells without additional conditioning is c
Autor:
Soumo Bhattacharya, Karl S. Peggs, Michael J. Watts, Kwee Yong, Shirley D'Sa, Stuart J. Ings, Kirit M. Ardeshna, Barbara Foulkes, Chara Kyriakou, Catherine D. Williams, Anthony H. Goldstone
Publikováno v:
British Journal of Haematology. 125:756-765
Myeloma remains incurable with a median survival of 4 years, but outcome can be improved by the use of high-dose therapy. We used the etoposide, methylprednisolone, cytarabine and cisplatin (ESHAP) regimen as second-line therapy in 42 newly diagnosed
Autor:
Kwee Yong, Stuart J. Ings, Tim C. P. Somervaille, Forhad Ahmed, Michael J. Watts, Asim Khwaja, David C. Linch
Publikováno v:
British Journal of Haematology. 118:117-123
The two clinical scale devices currently available for CD34+ cell selection from peripheral blood stem cells (PBSC) apheresis products, the CliniMACS and the Isolex 300i, were compared directly by pooling and splitting two PBSC harvests collected on
Autor:
Stephen Mackinnon, Geoff Hale, Panos Kottaridis, Ronjon Chakraverty, Ah Goldstone, Michael J. Watts, Stuart J. Ings, KS Peggs, Herman Waldmann, Dc Linch, S Robinson
Publikováno v:
Bone Marrow Transplantation. 28:827-834
We evaluated the outcome of two modes of T cell depletion for HLA-identical sibling stem cell transplants in 34 consecutive adult patients: group A (n = 11) received PBSC post CliniMACs immuno-magnetic enrichment of CD34(+) cells and group B (n = 23)
Publikováno v:
British Journal of Haematology. 111:287-291
A significant proportion of previously treated patients fail to mobilize sufficient stem/progenitor cells to enable high-dose therapy and peripheral blood stem cell transplantation to be performed. In this study, the value of remobilizing such patien
Publikováno v:
Blood. 91:1196-1205
The transmigration of hematopoietic progenitor cells (HPCs) across vascular endothelium is a critical step in the homing of transplanted stem cells, but the molecular basis for this is unknown. We used mobilized peripheral blood CD34+ selected cells