Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Stuart Hossack"'
Autor:
Nathan Gale, Mike McEwan, Alison C. Eldridge, Neil Sherwood, Edward Bowen, Simon McDermott, Emma Holmes, Andrew Hedge, Stuart Hossack, Oscar M. Camacho, Graham Errington, John McAughey, James Murphy, Chuan Liu, Christopher J. Proctor, Ian M. Fearon
Publikováno v:
BMC Public Health, Vol 17, Iss 1, Pp 1-18 (2017)
Abstract Background Smoking is a leading cause of numerous human disorders including lung cancer, chronic obstructive pulmonary disease, and atherosclerotic cardiovascular disease. The development of modified risk tobacco products (MRTPs) has been su
Externí odkaz:
https://doaj.org/article/262416f1d095480c9feef5dc6351bd08
Autor:
Paolo Mulatero, Michael Groessl, Bruno Vogt, Christoph Schumacher, Ronald Edward Steele, Ashley Brooks, Stuart Hossack, Hans‐Rudolf Brunner
Publikováno v:
British Journal of Clinical Pharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c33179d57a648c2ae8f571736bd34bc5
https://doi.org/10.1111/bcp.15713
https://doi.org/10.1111/bcp.15713
Autor:
Oscar M. Camacho, Simon McDermott, John McAughey, Chuan Liu, Emma Holmes, Graham Errington, Stuart Hossack, James Murphy, Edward Bowen, Alison Eldridge, Mike McEwan, Ian M. Fearon, Andrew Hedge, Christopher Proctor, Nathan Gale, Neil Sherwood
Publikováno v:
BMC Public Health, Vol 17, Iss 1, Pp 1-18 (2017)
BMC Public Health
BMC Public Health
Background Smoking is a leading cause of numerous human disorders including lung cancer, chronic obstructive pulmonary disease, and atherosclerotic cardiovascular disease. The development of modified risk tobacco products (MRTPs) has been suggested a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78abbeeea51fa8f3be5aaa8827933715
http://link.springer.com/article/10.1186/s12889-017-4678-9
http://link.springer.com/article/10.1186/s12889-017-4678-9
Autor:
Andrew Griffin, Stuart Hossack, Richard L. Leff, Dan A. Chiche, Philippe Walker, Roxane Aubray, William Brown
Publikováno v:
The Journal of Pain. 18:726-738
Most previous transient receptor potential vanilloid subtype 1 (TRPV1) antagonist programs have been put on hold, mainly because of on-target adverse events: hyperthermia and impaired noxious heat sensation. NEO6860 is a TRPV1 antagonist, blocking ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::806a7f330d119b3e0ec9c141e25ea1af
https://doi.org/10.1016/j.jpain.2017.01.009
https://doi.org/10.1016/j.jpain.2017.01.009
Autor:
Neil Sherwood, Chuan Liu, James Glew, Simon McDermott, Emma Holmes, Nathan Gale, Andrew Hedge, Stuart Hossack, Louise Wakenshaw, Edward Bowen, Ian M. Fearon, Mike McEwan, Christopher Proctor, Graham Errington, Alison Eldridge, Oscar M. Camacho, John McAughey, James Murphy
Publikováno v:
Nicotine & Tobacco Research
Background Smoking is a leading cause of numerous human disorders including pulmonary disease, cardiovascular disease, and cancer. Disease development is primarily caused by exposure to cigarette smoke constituents, many of which are known toxicants.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db992be2914ffee6dcccdc4cd741cf21
https://pubmed.ncbi.nlm.nih.gov/29912406
https://pubmed.ncbi.nlm.nih.gov/29912406
Autor:
Mark Voskoboynik, Hendrik-Tobias Arkenau, Alastair Greystoke, Karen So, Ruth Plummer, Nicola Steele, Raffaele Califano, Emma Dean, Dana Ghiorghiu, Fiona H Blackhall, Stuart Hossack, Colin R Lindsay, Angela W. Dymond, Noor Md Haris, Yvonne Summers
Publikováno v:
British Journal of Cancer
Dean, E, Steele, N, Arkenau, H-T, Blackhall, F, Lindsay, C, Saggese, M, Califano, R, Greystoke, A, Voskoboynik, M, Ghiorghiu, D, Dymond, A, Smith, I & Plummer, R 2017, ' SELECT-3: a phase I study of selumetinib in combination with platinum-doublet chemotherapy for advanced NSCLC in the first-line setting. ', British Journal of Cancer, pp. 938-946 . https://doi.org/10.1038/bjc.2017.271
Dean, E, Steele, N, Arkenau, H-T, Blackhall, F, Lindsay, C, Saggese, M, Califano, R, Greystoke, A, Voskoboynik, M, Ghiorghiu, D, Dymond, A, Smith, I & Plummer, R 2017, ' SELECT-3: a phase I study of selumetinib in combination with platinum-doublet chemotherapy for advanced NSCLC in the first-line setting. ', British Journal of Cancer, pp. 938-946 . https://doi.org/10.1038/bjc.2017.271
BACKGROUND: We investigated selumetinib (AZD6244, ARRY-142886), an oral, potent, and highly selective, allosteric MEK1/2 inhibitor, plus platinum-doublet chemotherapy for patients with advanced/metastatic non-small cell lung cancer.METHODS: In this P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::532e3b9fe5e5e471373fb944e77f9a52
https://pubmed.ncbi.nlm.nih.gov/28950288
https://pubmed.ncbi.nlm.nih.gov/28950288
Autor:
Carmen Cuffari, Alena Y Z Edwards, David M. Pierce, Stuart Hossack, Hong Wan, Patrick Martin, Heather Van Heusen, Krzysztof Fyderek, Bartosz Korczowski
Publikováno v:
Drug Design, Development and Therapy
Carmen Cuffari,1 David Pierce,2 Bartosz Korczowski,3 Krzysztof Fyderek,4 Heather Van Heusen,5 Stuart Hossack,6 Hong Wan,5 Alena YZ Edwards,7 Patrick Martin5 1Department of Pediatrics, Division of Pediatric Gastroenterology and Nutrition, The Johns Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2f93096a172fe82775f97c1afef329b
https://www.dovepress.com/randomized-clinical-trial-pharmacokinetics-and-safety-of-multimatrix-m-peer-reviewed-article-DDDT
https://www.dovepress.com/randomized-clinical-trial-pharmacokinetics-and-safety-of-multimatrix-m-peer-reviewed-article-DDDT
The effect of sevelamer carbonate and lanthanum carbonate on the pharmacokinetics of oral calcitriol
Autor:
Antoine Robinson, Michael Smyth, Lynne Poole, Heather Van Heusen, Patrick Martin, David M. Pierce, Stuart Hossack
Publikováno v:
Nephrology Dialysis Transplantation
Background. Lanthanum carbonate and sevelamer carbonate are non-calcium-based phosphate binders used to manage hyperphosphataemia in patients with chronic kidney disease (CKD). Patients with CKD may require intravenous or oral active vitamin D. We in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9516150c77bae03279896123e233df16
https://doi.org/10.1093/ndt/gfq598
https://doi.org/10.1093/ndt/gfq598
Autor:
Igor Ivanisevic, Stephen R. Byrn, David Engers, Jonathan Jimenez-Novoa, Ann Newman, Cheryl Campbell, Philip Gent, John Thomson, Jing Teng, Alison Templeton, Stuart Hossack
Publikováno v:
Journal of Pharmaceutical Sciences. 99:3901-3922
A solid-state approach to enable compounds in preclinical development is used by identifying an amorphous solid dispersion in a simple formulation to increase bioavailability. Itraconazole (ITZ) was chosen as a model crystalline compound displaying p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f331610905bf23b9e4af3173d085fd5f
https://doi.org/10.1002/jps.22233
https://doi.org/10.1002/jps.22233
Autor:
Patrick Martin, Stuart Hossack, David M. Pierce, Mieke Hoppenbrouwers, Maria Velinova, Mary Corcoran
Publikováno v:
Drug Design, Development and Therapy
David Pierce,1 Mary Corcoran,2 Maria Velinova,3 Stuart Hossack,4 Mieke Hoppenbrouwers,5 Patrick Martin,21Shire, Basingstoke, UK; 2Shire, Wayne, PA, USA; 3PRA International, Zuidlaren, the Netherlands; 4Covance, Leeds, UK; 5Shire-Movetis NV, Turnhout,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c542ad33a5bcf599b2d1a45a53f13a7
https://pubmed.ncbi.nlm.nih.gov/25767373
https://pubmed.ncbi.nlm.nih.gov/25767373