Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Stuart G. Fischer"'
Autor:
Wendy K. Chung, Minyoung Shin, Thomas C. Jaramillo, Rudolph L. Leibel, Charles A. LeDuc, Stuart G. Fischer, Efthia Tzilianos, Ayman A. Gheith, Alan S. Lewis, Dane M. Chetkovich
Publikováno v:
Neurobiology of Disease, Vol 33, Iss 3, Pp 499-508 (2009)
Analysis of naturally occurring mutations that cause seizures in rodents has advanced understanding of the molecular mechanisms underlying epilepsy. Abnormalities of Ih and h channel expression have been found in many animal models of absence epileps
Externí odkaz:
https://doaj.org/article/48c1e721331045fa8ebf02b07eeda6e1
Autor:
Elizabeth J Millings, Maria Caterina De Rosa, Sarah Fleet, Kazuhisa Watanabe, Richard Rausch, Dieter Egli, Gen Li, Charles A Leduc, Yiying Zhang, Stuart G Fischer, Rudolph L Leibel
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197548 (2018)
We have previously reported that Ildr2 knockdown via adenovirally-delivered shRNA causes hepatic steatosis in mice. In the present study we investigated hepatic biochemical and anatomic phenotypes of Cre-mediated Ildr2 knock-out mice. Liver-specific
Externí odkaz:
https://doaj.org/article/66d806134ca748b497d61b5b6864b91d
Autor:
Kazuhisa Watanabe, Elizabeth Watson, Maria Laura Cremona, Elizabeth J Millings, Jay H Lefkowitch, Stuart G Fischer, Charles A LeDuc, Rudolph L Leibel
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67234 (2013)
Ildr2, a modifier of diabetes susceptibility in obese mice, is expressed in most organs, including islets and hypothalamus, with reduced levels in livers of diabetes-susceptible B6.DBA mice congenic for a 1.8 Mb interval of Chromosome 1. In hepatoma
Externí odkaz:
https://doaj.org/article/404c84fb376d47839b7f217b0be66723
Autor:
Marija Dokmanovic-Chouinard, Wendy K Chung, Jean-Claude Chevre, Elizabeth Watson, Jason Yonan, Beebe Wiegand, Yana Bromberg, Nao Wakae, Chris V Wright, John Overton, Sujoy Ghosh, Ganesh M Sathe, Carina E Ammala, Kathleen K Brown, Rokuro Ito, Charles LeDuc, Keely Solomon, Stuart G Fischer, Rudolph L Leibel
Publikováno v:
PLoS Genetics, Vol 4, Iss 7, p e1000137 (2008)
In 404 Lep(ob/ob) F2 progeny of a C57BL/6J (B6) x DBA/2J (DBA) intercross, we mapped a DBA-related quantitative trait locus (QTL) to distal Chr1 at 169.6 Mb, centered about D1Mit110, for diabetes-related phenotypes that included blood glucose, HbA1c,
Externí odkaz:
https://doaj.org/article/4a3d3fd680ac4af0ac0d66f6d71e27d2
Autor:
Charles A. LeDuc, Sadahiko Iwamoto, Supichaya Boonvisut, Elizabeth J. Millings, Stuart G. Fischer, Kazuhiro Nakayama, Kazuhisa Watanabe, Satoshi Ohta, Rudolph L. Leibel, Kenji Tago
Publikováno v:
Biochemical and biophysical research communications. 477(4)
A diabetes susceptibility gene, immunoglobulin-like domain containing receptor 2 (Ildr2), encodes a transmembrane protein localized to the endoplasmic reticulum membrane that is closely related to hepatic lipid metabolism. The livers of ob/ob mice in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca6620bd9c127457a0da585a8552c323
https://pubmed.ncbi.nlm.nih.gov/27353377
https://pubmed.ncbi.nlm.nih.gov/27353377
Autor:
Rudolph L. Leibel, Kazuhisa Watanabe, Richard Rausch, Charles A. LeDuc, Sarah E. Fleet, Maria Caterina De Rosa, Gen Li, Stuart G. Fischer, Elizabeth J. Millings, Yiying Zhang, Dieter Egli
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197548 (2018)
PLoS ONE
PLoS ONE
We have previously reported that Ildr2 knockdown via adenovirally-delivered shRNA causes hepatic steatosis in mice. In the present study we investigated hepatic biochemical and anatomic phenotypes of Cre-mediated Ildr2 knock-out mice. Liver-specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0618950722ffa116292069551f3b3073
https://doi.org/10.1371/journal.pone.0197548
https://doi.org/10.1371/journal.pone.0197548
Autor:
Rudolph L. Leibel, Minyoung Shin, Dane M. Chetkovich, Alan S. Lewis, Wendy K. Chung, Charles A. LeDuc, Efthia Tzilianos, Ayman A. Gheith, Stuart G. Fischer, Thomas C. Jaramillo
Publikováno v:
Neurobiology of Disease, Vol 33, Iss 3, Pp 499-508 (2009)
Analysis of naturally occurring mutations that cause seizures in rodents has advanced understanding of the molecular mechanisms underlying epilepsy. Abnormalities of Ih and h channel expression have been found in many animal models of absence epileps
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2352a429ea5caaf47dec5e84282d75d0
http://www.sciencedirect.com/science/article/pii/S0969996108003082
http://www.sciencedirect.com/science/article/pii/S0969996108003082
Autor:
Homin K. Lee, Abraham A. Palmer, K. C. Smith, Stuart G. Fischer, Amanda L. Yonan, T. C. Gilliam, Paul Pavlidis, J. M. Yonan, I. Feldman
Publikováno v:
Genes, Brain and Behavior. 2:303-320
Common genetic disorders are believed to arise from the combined effects of multiple inherited genetic variants acting in concert with environmental factors, such that any given DNA sequence variant may have only a marginal effect on disease outcome.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8c34ae80e36d92925fdc659310c6d42
https://doi.org/10.1034/j.1601-183x.2003.00041.x
https://doi.org/10.1034/j.1601-183x.2003.00041.x
Autor:
Ana Kljuic, Vincent M. Aita, Wasim Ahmad, T. Conrad Gilliam, Stuart G. Fischer, Hisham Bazzi, Xavier Montagutelli, Angela M. Christiano, Rebecca J. Morris, Moise L. Levy, Amalia Martinez-Mir, My G. Mahoney, Ryan F.L. O'Shaughnessy, Jouni Uitto, Jurg Ott, Andrei A. Panteleyev, Derek Gordon, Vu Thuong Nguyen, John P. Sundberg, Colin A.B. Jahoda, David A. Whiting
Publikováno v:
Cell. 113(2):249-260
Cell adhesion and communication are interdependent aspects of cell behavior that are critical for morphogenesis and tissue architecture. In the skin, epidermal adhesion is mediated in part by specialized cell-cell junctions known as desmosomes, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003072e3ef83c18fdfeabaeb210e78bf
Autor:
Gil Segal, Gifty Asamani, Stuart G. Fischer, Hye Park, Anthi Georghiou, Pieter J. deJong, Irina Morozova, Justin Rineer, Jing Chen, Minchen Chen, Howard A. Shuman, Marc Feder, Joseph J. Greenberg, Eftihia Cayanis, Andrey Rzhetsky, Xiaoyan Qu, Peisen Zhang, Curtis Goldsberry, James J. Russo, Sergey Kalachikov
This chapter aims at obtaining the complete sequence of the Philadelphia 1 strain of Legionella pneumophila, derived from the original 1976 outbreak that established the clinical entity known as Legionnaires' disease. The GC content of L. pneumophila
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79196377fe1b7267f6c38269c3d62af1
https://doi.org/10.1128/9781555817985.ch19
https://doi.org/10.1128/9781555817985.ch19
