Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Stuart F.J. Le Grice"'
Autor:
Fardokht Abulwerdi, Farzad Fatehi, Iain W. Manfield, Stuart F.J. Le Grice, John S. Schneekloth, Reidun Twarock, Peter G. Stockley, Nikesh Patel
Publikováno v:
Data in Brief, Vol 42, Iss , Pp 108206- (2022)
Multiple ssRNA viruses which infect bacteria, plants or humans use RNA Packaging Signal (PS)-mediated regulation during assembly to package their genomes faithfully and efficiently. PSs typically comprise short nucleotide recognition motifs, most oft
Externí odkaz:
https://doaj.org/article/1f4a24cc33804de5b1e26862f06ae21e
Publikováno v:
Viruses, Vol 8, Iss 7, p 193 (2016)
Long-terminal repeat (LTR) retrotransposons are transposable genetic elements that replicate intracellularly, and can be considered progenitors of retroviruses. Ty1 and Ty3 are the most extensively characterized LTR retrotransposons whose RNA genomes
Externí odkaz:
https://doaj.org/article/01bec62124574155a04fe37a94ec94bf
Publikováno v:
Current HIV Research. 18:69-73
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33d6dd5a40cddf2829d916b95533622d
https://doi.org/10.2174/1570162x1802200311104204
https://doi.org/10.2174/1570162x1802200311104204
Autor:
Hao Li, Chringma Sherpa, Stuart F.J. Le Grice, Ashley N. Peralta, Yumin Dai, Webster L. Santos, Jessica E. Wynn, Astha Verma
Publikováno v:
Bioorganic & Medicinal Chemistry. 27:1759-1765
Interaction of HIV-1 rev response element (RRE) RNA with its cognate protein, Rev, is critical for HIV-1 replication. Understanding the mode of interaction between RRE RNA and ligands at the binding site can facilitate RNA molecular recognition as we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::759d9f935ddcaab6ce5648f06b24347c
https://doi.org/10.1016/j.bmc.2019.03.016
https://doi.org/10.1016/j.bmc.2019.03.016
Autor:
Abeer Ageeli, Monalisa Swain, Michael J. Yonkunas, Wojciech Kasprzak, Kayleigh McGovern-Gooch, Bruce A. Shapiro, Stuart F.J. Le Grice, Nathan Baird
Publikováno v:
Biophysical Journal. 121:166a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c377ea3a6a1ce6901c8437144cc489cc
https://doi.org/10.1016/j.bpj.2021.11.1896
https://doi.org/10.1016/j.bpj.2021.11.1896
Autor:
Hao Li, Alan D. Frankel, Yumin Dai, Webster L. Santos, Chringma Sherpa, Stuart F.J. Le Grice, Bhargavi Jayaraman, Astha Verma, Jessica E. Wynn, Ashley N. Peralta
Publikováno v:
Journal of Medicinal Chemistry. 61:9611-9620
We synthesized and screened a unique 46 656-member library composed of unnatural amino acids that revealed several hits against RRE IIB RNA. Among the hit peptides identified, peptide 4A5 was found to be selective against competitor RNAs and inhibite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d9f804575b97ccb3fcb88438902fb12
https://doi.org/10.1021/acs.jmedchem.8b01076
https://doi.org/10.1021/acs.jmedchem.8b01076
Autor:
Stuart F.J. Le Grice, Chringma Sherpa
Publikováno v:
Current HIV research. 18(2)
The vast genetic variability of HIV has impeded efforts towards a cure for HIV. Lifelong administration of combined antiretroviral therapy (cART) is highly effective against HIV and has markedly increased the life expectancy of HIV infected individua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20e6f294278e6a1313f935eb3fd46fbd
https://pubmed.ncbi.nlm.nih.gov/32039686
https://pubmed.ncbi.nlm.nih.gov/32039686
Autor:
Jason W. Rausch, Stuart F.J. Le Grice
Publikováno v:
Current HIV Research
Modern combination antiretroviral therapy (cART) can bring HIV-1 in blood plasma to level undetectable by standard tests, prevent the onset of acquired immune deficiency syndrome (AIDS), and allow a near-normal life expectancy for HIV-infected indivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7774f74c7add2f1c3f218bf39afecc5
https://pubmed.ncbi.nlm.nih.gov/31889490
https://pubmed.ncbi.nlm.nih.gov/31889490
Autor:
Laurie R. Gray, Chringma Sherpa, Kathryn Anastos, David Rekosh, Stuart F.J. Le Grice, Marie-Louise Hammarskjold, Patrick E. H. Jackson
Publikováno v:
Journal of Virology. 93
The HIV-1 Rev response element (RRE) is a cis-acting RNA element characterized by multiple stem-loops. Binding and multimerization of the HIV Rev protein on the RRE promote the nucleocytoplasmic export of incompletely spliced mRNAs, an essential step
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f66c3e522fa911d4219026b88f81170d
https://doi.org/10.1128/jvi.02102-18
https://doi.org/10.1128/jvi.02102-18