Zobrazeno 1 - 10
of 410
pro vyhledávání: '"Stuart E Turvey"'
Autor:
Ye Peng, Hein M Tun, Siew C Ng, Hogan Kok-Fung Wai, Xi Zhang, Jaclyn Parks, Catherine J Field, Piush Mandhane, Theo J Moraes, Elinor Simons, Stuart E Turvey, Padmaja Subbarao, Jeffrey R Brook, Tim K Takaro, James A Scott, Francis KL Chan, Anita L Kozyrskyj
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTChildhood obesity is linked to maternal smoking during pregnancy. Gut microbiota may partially mediate this association and could be potential targets for intervention; however, its role is understudied. We included 1,592 infants from the Can
Externí odkaz:
https://doaj.org/article/b77c695a37b84ae1bdc381cb24872a84
Autor:
Wei Q Deng, Nathan Cawte, Natalie Campbell, Sandi M Azab, Russell J de Souza, Amel Lamri, Katherine M Morrison, Stephanie A Atkinson, Padmaja Subbarao, Stuart E Turvey, Theo J Moraes, Koon K Teo, Piush J Mandhane, Meghan B Azad, Elinor Simons, Guillaume Paré, Sonia S Anand
Publikováno v:
eLife, Vol 13 (2024)
Background: Maternal smoking has been linked to adverse health outcomes in newborns but the extent to which it impacts newborn health has not been quantified through an aggregated cord blood DNA methylation (DNAm) score. Here, we examine the feasibil
Externí odkaz:
https://doaj.org/article/fd664229366a4b9486dd73f32c0da18c
Autor:
Sandi M Azab, Meera Shanmuganathan, Russell J de Souza, Zachary Kroezen, Dipika Desai, Natalie C Williams, Katherine M Morrison, Stephanie A Atkinson, Koon K Teo, Meghan B Azad, Elinor Simons, Theo J Moraes, Piush J Mandhane, Stuart E Turvey, Padmaja Subbarao, Philip Britz-McKibbin, Sonia S Anand
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-10 (2023)
Abstract Background Childhood obesity is a global health concern and can lead to lifetime cardiometabolic disease. New advances in metabolomics can provide biochemical insights into the early development of obesity, so we aimed to characterize serum
Externí odkaz:
https://doaj.org/article/af6d3e803bc74e65ac64b8014ecf71fc
Autor:
Loubna Akhabir, Randa Stringer, Dipika Desai, Piush J Mandhane, Meghan B Azad, Theo J Moraes, Padmaja Subbarao, Stuart E Turvey, Guillaume Paré, Sonia S. Anand, for the NutriGen Alliance
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-9 (2022)
Abstract Background Environmental exposures in utero which modify DNA methylation may have a long-lasting impact on health and disease in offspring. We aimed to identify and replicate previously published genomic loci where DNA methylation changes ar
Externí odkaz:
https://doaj.org/article/d304c81831e847839453916db90b99ba
Autor:
Sascha Kahlfuss, Ulrike Kaufmann, Axel R Concepcion, Lucile Noyer, Dimitrius Raphael, Martin Vaeth, Jun Yang, Priya Pancholi, Mate Maus, James Muller, Lina Kozhaya, Alireza Khodadadi‐Jamayran, Zhengxi Sun, Patrick Shaw, Derya Unutmaz, Peter B Stathopulos, Cori Feist, Scott B Cameron, Stuart E Turvey, Stefan Feske
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 8, Pp 1-25 (2020)
Abstract Immunity to fungal infections is mediated by cells of the innate and adaptive immune system including Th17 cells. Ca2+ influx in immune cells is regulated by stromal interaction molecule 1 (STIM1) and its activation of the Ca2+ channel ORAI1
Externí odkaz:
https://doaj.org/article/5dea67d69b0a4240ad6b7dfd0ac39c79
Autor:
Mon H Tun, Radha Chari, Padma Kaul, Fabiana V Mamede, Mike Paulden, Diana L Lefebvre, Stuart E Turvey, Theo J Moraes, Malcolm R Sears, Padmaja Subbarao, Piush J Mandhane
Publikováno v:
PLoS ONE, Vol 17, Iss 10, p e0268229 (2022)
IntroductionPreviously developed cesarean section (CS) and emergency CS prediction tools use antenatal and intrapartum risk factors. We aimed to develop a predictive model for the risk of emergency CS before the onset of labour utilizing antenatal ob
Externí odkaz:
https://doaj.org/article/95a35623f62c49079e8243c942d7361b
Autor:
Stuart E Turvey, Padmaja Subbarao, Malcolm R Sears, Theo J Moraes, Amin Adibi, Piush J Mandhane, Tae Yoon Lee, Allen B Becker
Publikováno v:
BMJ Open Respiratory Research, Vol 8, Iss 1 (2021)
Externí odkaz:
https://doaj.org/article/8f2ff2c8245b4196b1c8417940ff2667
Autor:
Rozlyn CT Boutin, Charisse Petersen, Sarah E Woodward, Antonio Serapio-Palacios, Tahereh Bozorgmehr, Rachelle Loo, Alina Chalanuchpong, Mihai Cirstea, Bernard Lo, Kelsey E Huus, Weronika Barcik, Meghan B Azad, Allan B Becker, Piush J Mandhane, Theo J Moraes, Malcolm R Sears, Padmaja Subbarao, Kelly M McNagny, Stuart E Turvey, B Brett Finlay
Publikováno v:
eLife, Vol 10 (2021)
Bacterial members of the infant gut microbiota and bacterial-derived short-chain fatty acids (SCFAs) have been shown to be protective against childhood asthma, but a role for the fungal microbiota in asthma etiology remains poorly defined. We recentl
Externí odkaz:
https://doaj.org/article/3528669980c6489896b4811b6c6f4526
Autor:
Michael A Zulyniak, Russell J de Souza, Mateen Shaikh, Chinthanie Ramasundarahettige, Keith Tam, Natalie Williams, Dipika Desai, Diana L Lefebvre, Milan Gupta, Padmaja Subbarao, Allan B Becker, Piushkumar J Mandhane, Stuart E Turvey, Theo Moraes, Meghan B Azad, Koon K Teo, Malcolm R Sears, Sonia S Anand, NutriGen Alliance investigators
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232170 (2020)
BackgroundThe global prevalence of childhood eczema has increased over the last few decades, with a marked increase in high-income countries. Differences in prevalence of childhood eczema between countries and ethnicities suggest that genetic and ear
Externí odkaz:
https://doaj.org/article/3e636de77d194e5f99a98df5aeb16f70
Autor:
Aabida Saferali, Anthony C Tang, Lisa J Strug, Bradley S Quon, James Zlosnik, Andrew J Sandford, Stuart E Turvey
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227067 (2020)
BackgroundCystic fibrosis (CF) is characterized by a progressive decline in lung function due to airway obstruction, infection, and inflammation. CF patients are particularly susceptible to respiratory infection by a variety of pathogens, and the inf
Externí odkaz:
https://doaj.org/article/bcf7bf9a332b49dd9fbc25045860ebbc