Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Stuart Dias"'
Autor:
Seth L. Masters, Andrew W. Roberts, Marc Pellegrini, Stuart Dias, Jian-Guo Zhang, Louise H. Cengia, Catherine Kennedy, Ben A. Croker, Motti Gerlic, Elizabeth L. Hartland, Cameron J. Nowell, Joanne A. O’Donnell, Lorraine A. O'Reilly
Publikováno v:
Journal of Leukocyte Biology. 97:321-326
Neutrophils use Toll-like receptor and IL-18 signaling to reprogram Fas-induced death. The regulation of neutrophil lifespan is critical for a circumscribed immune response. Neutrophils are sensitive to Fas/CD95 death receptor signaling in vitro, but
Publikováno v:
Leukemia
Cytokines secreted by bone marrow stromal cells protect c-KIT mutant AML cells from c-KIT inhibitor-induced apoptosis
Autor:
Deepti Banka, Scott A. Armstrong, Nan Zhu, Ali Cihan, Chun-Wei Chen, Robert G. Roeder, Anagha Deshpande, Maurizio Fazio, Minkui Luo, Gloria Ibáñez, Aniruddha J. Deshpande, Jenny Chang, Andrei V. Krivtsov, Liying Chen, Kathrin M. Bernt, Liuda Dzhekieva, Amit U. Sinha, Richard Koche, James E. Bradner, Stuart Dias
SummaryHomeotic (HOX) genes are dysregulated in multiple malignancies, including several AML subtypes. We demonstrate that H3K79 dimethylation (H3K79me2) is converted to monomethylation (H3K79me1) at HOX loci as hematopoietic cells mature, thus coinc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88868ac296b2fd47a861603107b20e8f
https://europepmc.org/articles/PMC4291116/
https://europepmc.org/articles/PMC4291116/
Autor:
Jenny Chang, Scott A. Armstrong, Demetrios Kalaitzidis, Andrei V. Krivtsov, Amit U. Sinha, Stuart Dias, Cherry Ee Lin Ng
The targeting of self-renewal pathways commonly activated in leukemia serves as a potential strategy for multiple subtypes of this disease regardless of genetic, clonal, or cellular heterogeneity. Elevation of β-catenin above physiological condition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c11e6aef77e241a93e9aee38d535238f
https://europepmc.org/articles/PMC4367949/
https://europepmc.org/articles/PMC4367949/
Autor:
Kathrin M. Bernt, Edward J. Olhava, Stuart Dias, Victoria M. Richon, Deepti Banka, Christian Buske, Roy M. Pollock, Liying Chen, Aniruddha J. Deshpande, Scott R. Daigle, Scott A. Armstrong
Publikováno v:
Leukemia. 27(4)
The t(10;11)(p12;q23) translocation and the t(10;11)(p12;q14) translocation, which encode the MLL (mixed lineage leukemia)-AF10 and CALM (clathrin assembly lymphoid myeloid leukemia)-AF10 fusion oncoproteins, respectively, are two recurrent chromosom
Autor:
Victoria M. Richon, Liying Chen, Scott R. Daigle, Kathrin M. Bernt, Edward J. Olhava, Deepti Banka, Stuart Dias, Roy M. Pollock, Aniruddha J. Deshpande, Scott A. Armstrong, Maurizio Fazio, Amit U. Sinha
Publikováno v:
Blood. 120:3502-3502
Abstract 3502 The t(6;11)(q27;q23) produces a chimeric MLL-AF6 oncogene, and is a recurrent chromosomal rearrangement observed in patients with diverse hematologic malignancies such as acute myelogenous leukemia (AML), as well as both B-cell and T-ce
Autor:
Edward J. Olhava, Liying Chen, Christian Buske, Deepti Banka, Victoria M. Richon, Roy M. Pollock, Stuart Dias, Bernt Kathrin, Aniruddha J. Deshpande, Scott A. Armstrong, Scott R. Daigle
Publikováno v:
Blood. 120:2384-2384
Abstract 2384 The t(10;11)(p12;q23) and the t(10;11)(p12;q14), which encode the MLL-AF10 and CALM-AF10 fusion oncoproteins respectively, are two recurrent chromosomal rearrangements observed in patients with acute myeloid leukemia (AML) and acute lym