Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Stuart Cain"'
Autor:
Joseph Kelleher, Adam Dickinson, Stuart Cain, Yanhua Hu, Nicola Bates, Adam Harvey, Jianzhen Ren, Wenjun Zhang, Fiona C. Moreton, Keith W. Muir, Christopher Ward, Rhian M. Touyz, Pankaj Sharma, Qingbo Xu, Susan J. Kimber, Tao Wang
Publikováno v:
Stem Cell Reports, Vol 13, Iss 5, Pp 817-831 (2019)
Summary: CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) is the most common form of genetic stroke and vascular dementia syndrome resulting from mutations in NOTCH3. To elucidate molecular mechanis
Externí odkaz:
https://doaj.org/article/5f1aead6558d4738a4ebf3c5651b3e21
Autor:
Agustin Garcia-Caballero, Fang-Xiong Zhang, Victoria Hodgkinson, Junting Huang, Lina Chen, Ivana A. Souza, Stuart Cain, Jennifer Kass, Sascha Alles, Terrance P. Snutch, Gerald W. Zamponi
Publikováno v:
Molecular Brain, Vol 11, Iss 1, Pp 1-10 (2018)
Abstract This study describes the functional interaction between the Cav3.1 and Cav3.2 T-type calcium channels and cytoskeletal spectrin (α/β) and ankyrin B proteins. The interactions were identified utilizing a proteomic approach to identify prote
Externí odkaz:
https://doaj.org/article/ac77eff5edbc4bdca51628849a3670ac
Autor:
Elena Redondo-Castro, Catriona Cunningham, Jonjo Miller, Stuart Cain, Stuart Allan, Emmanuel Pinteaux
Publikováno v:
Bio-Protocol, Vol 8, Iss 16 (2018)
The 3D culture of human mesenchymal stem cells (hMSCs) represents a more physiological environment than classical 2D culture and has been used to enhance the MSC secretome or extend cell survival after transplantation. Here we describe a simple and a
Externí odkaz:
https://doaj.org/article/be24da871d7d4b69bc9179eaf0d568e9
Autor:
Stuart Cain, Paul Humphreys, Mark Naven, Christopher Andrew Smith, Mona Dvir-Ginzberg, Susan Kimber, Nicola Bates
Publikováno v:
Smith, C A, Humphreys, P A, Bates, N, Naven, M A, Cain, S A, Dvir-Ginzberg, M & Kimber, S J 2022, ' SIRT1 activity orchestrates ECM expression during hESC-chondrogenic differentiation ', FASEB Journal, vol. 36, no. 5, e22314 . https://doi.org/10.1096/fj.202200169R
Epigenetic modification is a key driver of differentiation, and the deacetylase Sirtuin1 (SIRT1) is an established regulator of cell function, ageing, and articular cartilage homeostasis. Here we investigate the role of SIRT1 during development of ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8640ac0fe96463f3b4900d1015b2b4bf
https://pubmed.ncbi.nlm.nih.gov/35416346
https://pubmed.ncbi.nlm.nih.gov/35416346
Publikováno v:
Journal of Hydraulic Engineering. 137:66-74
The results of a numerical model study of probable maximum flood (PMF) flow through a system of spillways consisting of an existing service spillway and a new auxiliary spillway are presented. A commercial computational fluid dynamics (CFD) code, Flu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a124c09d6fd41259f63da546c372aeeb
https://doi.org/10.1061/(asce)hy.1943-7900.0000279
https://doi.org/10.1061/(asce)hy.1943-7900.0000279
Publikováno v:
Volume 3: Thermal Hydraulics; Current Advanced Reactors: Plant Design, Construction, Workforce and Public Acceptance.
High Energy Line Breaks (HELBs) inside nuclear reactor containment are recognized as challenges to Pressurized Water Reactor (PWR) and Boiling Water Reactor (BWR) nuclear power plants arising from the collateral damage due to insulation, fireproofing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::983f765fb707a601b40728c827212f07
https://doi.org/10.1115/icone17-75164
https://doi.org/10.1115/icone17-75164
Publikováno v:
Volume 3: Thermal Hydraulics; Current Advanced Reactors: Plant Design, Construction, Workforce and Public Acceptance.
In response to recent U.S. Nuclear Regulatory Commission (NRC) Component Design Bases Inspection (CBDI) issues, many US nuclear power stations have been required to demonstrate that minimum submergence requirements were properly determined for flow w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fef7ee3ad3ac5eb4f8744bb6f2addff
https://doi.org/10.1115/icone17-75169
https://doi.org/10.1115/icone17-75169
Publikováno v:
Energy Conversion and Resources.
High Energy Line Breaks (HELBs) inside nuclear reactor containment are recognized as challenges to Pressurized Water Reactor (PWR) nuclear power plants arising from the collateral damage due to insulation, fireproofing, coatings, and other miscellane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::138f8f6c8021ceb4d0b686214032ab24
https://doi.org/10.1115/imece2005-82912
https://doi.org/10.1115/imece2005-82912