Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Stuart C.G. Rison"'
Autor:
Borislava Mihaylova, Zahra Raisi-Estabragh, Stuart C.G. Rison, Chris Carvalho, John Robson, R Wu, I Dostal
Publikováno v:
European Heart Journal. 42
Background Hypertension and hypercholesterolaemia are major modifiable risk factors for cardiovascular diseases (CVD) with available effective and low-cost treatments. However, their suboptimal treatment remains widespread. We characterise treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5a5689949834cc2a7fa56e73d36b93e
https://doi.org/10.1093/eurheartj/ehab724.2728
https://doi.org/10.1093/eurheartj/ehab724.2728
Autor:
Crystal Williams, John Robson, Riyaz S. Patel, Adam Timmis, Zahra Raisi-Estabragh, Chris Carvalho, Stuart C.G. Rison
Publikováno v:
Heart (British Cardiac Society).
ObjectiveThe Familial Hypercholesterolaemia Case Ascertainment Tool (FAMCAT) has been proposed to enhance case finding in primary care. In this study, we test application of the FAMCAT algorithm to describe risks of familial hypercholesterolaemia (FH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c1a906e8aa260322844980bba6c4e25
https://pubmed.ncbi.nlm.nih.gov/34016698
https://pubmed.ncbi.nlm.nih.gov/34016698
Publikováno v:
Microbiology
Identification of protein translation start sites is largely a bioinformatics exercise, with relatively few confirmed by N-terminal sequencing. Translation start site determination is critical for defining both the protein sequence and the upstream D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba939ce95af813b7108821315ad15f07
https://doi.org/10.1099/mic.0.2006/001537-0
https://doi.org/10.1099/mic.0.2006/001537-0
Publikováno v:
Nucleic Acids Research
An important step in understanding the regulation of a prokaryotic genome is the generation of its transcription unit map. The current strongest operon predictor depends on the distributions of intergenic distances (IGD) separating adjacent genes wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5ff7d3e30c826557b8110f298a547a5
https://doi.org/10.1093/nar/gki634
https://doi.org/10.1093/nar/gki634
Publikováno v:
Trends in Microbiology. 12:537-544
Bacterial pathogens adapt to their host environments to a large extent through switching on complex transcriptional programmes, and whole-genome microarray experiments promise to reveal this complexity. There has been a recent burst of articles repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30516541922d90fdb88be606812eb115
https://doi.org/10.1016/j.tim.2004.10.005
https://doi.org/10.1016/j.tim.2004.10.005
The Mycobacterium tuberculosis Rv1099c gene encodes a GlpX-like class II fructose 1,6-bisphosphatase
Autor:
Paul R. Wheeler, Stuart C.G. Rison, Neil G. Stoker, Farahnaz Movahedzadeh, Sharon L. Kendall, T. J. Larson
Publikováno v:
Microbiology. 150:3499-3505
There are now abundant data indicating that Mycobacterium tuberculosis uses fatty acids as a carbon source in vivo. A key enzyme in gluconeogenesis, missing in the original annotation of the M. tuberculosis genome, is fructose 1,6-bisphosphatase (FBP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59431e2a8dd6463031de5d950cfdea1a
https://doi.org/10.1099/mic.0.27204-0
https://doi.org/10.1099/mic.0.27204-0
Autor:
Yossef Av-Gay, Neil G. Stoker, Gregory J. Bancroft, Judith Murray-Rust, Richard A. Norman, Sharon L. Kendall, Farahnaz Movahedzadeh, Debbie A. Smith, Premkumar Dinadayala, Stuart C.G. Rison, Mamadou Daffe, Mark S. B. McAlister, Neil Q. McDonald, David G. Russell
Publikováno v:
Molecular Microbiology. 51:1003-1014
Inositol is utilized by Mycobacterium tuberculosis in the production of its major thiol and of essential cell wall lipoglycans. We have constructed a mutant lacking the gene encoding inositol-1-phosphate synthase (ino1), which catalyses the first com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb9e135f0a92a682f83b55bd23a29ef0
https://doi.org/10.1046/j.1365-2958.2003.03900.x
https://doi.org/10.1046/j.1365-2958.2003.03900.x
Autor:
Evangelos Simeonidis, Janet M. Thornton, I. David L. Bogle, Lazaros G. Papageorgiou, Stuart C.G. Rison
Publikováno v:
Metabolic Engineering. 5:211-219
The solution of the shortest path problem in biochemical systems constitutes an important step for studies of their evolution. In this paper, a linear programming (LP) algorithm for calculating minimal pathway distances in metabolic networks is studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a16180c1c3c17db23df3d0b174d38a7
https://doi.org/10.1016/s1096-7176(03)00043-0
https://doi.org/10.1016/s1096-7176(03)00043-0
Autor:
Janet M. Thornton, Christine A. Orengo, Adrian J. Shepherd, Frances M. G. Pearl, Daniel W. A. Buchan, David A. Lee, Stuart C.G. Rison
Publikováno v:
Genome Research. 12:503-514
We present a novel web-based resource,Gene3D, of precalculated structural assignments to gene sequences and whole genomes. This resource assigns structural domains from the CATH database to whole genes and links these to their curated functional and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd6aba6ab223175b0ed516e4ed7b68b0
https://doi.org/10.1101/gr.213802
https://doi.org/10.1101/gr.213802
Autor:
Julian Gough, Cyrus Chothia, Stuart C.G. Rison, Janet M. Thornton, Sarah A. Teichmann, Monica Riley
Publikováno v:
Trends in Biotechnology. 19:482-486
Escherichia coli has been a popular organism for studying metabolic pathways. In an attempt to find out more about how these pathways are constructed, the enzymes were analysed by defining their protein domains. Structural assignments and sequence co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce07d4515cf30b38583d8a04cae8701
https://doi.org/10.1016/s0167-7799(01)01813-3
https://doi.org/10.1016/s0167-7799(01)01813-3