Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Stuart Bussell"'
Publikováno v:
Connecticut medicine. 81(1)
The patient, a 43-year-old male, underwent uneventful laparoscopic right-sided hemicolectomy for a benign polyp, too large to be removed by colonoscopy. His postoperative course was uneventful; however, he returned 16 days after discharge with vague
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e50c66e99d5d206d42a1cd4825038e50
https://pubmed.ncbi.nlm.nih.gov/29782762
https://pubmed.ncbi.nlm.nih.gov/29782762
Autor:
Bruce E. Kimmel, Richard D. DiMarchi, Joel Berger, Anthony Manibusan, Zhihua Li, Qing Dallas-Yang, Margaret Wu, Dennis M. Zaller, Stuart Bussell, Jun Yao, Heather Myler, Anna-Maria A. Hays Putnam, James Mu, Nina Li, Bei B. Zhang, Thea Norman, Douglas W. Axelrod, Carlos G. Rodriguez, Jason Pinkstaff, Joseph M. Metzger, Darin Lee, Lillian Skidmore
Publikováno v:
Diabetes
Fibroblast growth factor 21 (FGF21) mitigates many of the pathogenic features of type 2 diabetes, despite a short circulating half-life. PEGylation is a proven approach to prolonging the duration of action while enhancing biophysical solubility and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e334765339a6145bf9956f15fddc608
http://europepmc.org/articles/PMC3266413
http://europepmc.org/articles/PMC3266413
Autor:
Thea Norman, Tsotne Javahishvili, Stuart Bussell, David C. Litzinger, Stephanie Chu, Bruce E. Kimmel, Ricky Lieu, Sami Kaphle, Bee-Cheng Sim, Peter G. Schultz, Thomas L. Daniel, Mike Ong, Anna-Maria A. Hays Putnam, Zhenwei Maio, Ying Buechler, Richard D. DiMarchi, Ho Cho, Andrew R. Hoffman, Guillermo Viramontes, Paola Castiglioni, Douglas W. Axelrod, Becky Gc, Vadim Kraynov, Nick Knudsen
Publikováno v:
Proceedings of the National Academy of Sciences. 108:9060-9065
The ribosomal incorporation of nonnative amino acids into polypeptides in living cells provides the opportunity to endow therapeutic proteins with unique pharmacological properties. We report here the first clinical study of a biosynthetic protein pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b5edb326f7ee27edbdf4cea0830975
https://doi.org/10.1073/pnas.1100387108
https://doi.org/10.1073/pnas.1100387108
Autor:
Heidi M. Hoffmann, Abigail Yu, Stellanie Krim, Cristina Abrahams, Maureen Fitch Bruhns, Millicent Embry, Toni Kline, Ryan Stafford, Arturo Molina, Shannon Matheny, Alice Yam, Venita I. DeAlmeida, Trevor J. Hallam, Mark Lupher, Stuart Bussell, Xiaofan Li, James Zawada
Publikováno v:
Cancer Research. 77:67-67
CD74 is a type II transmembrane glycoprotein involved in the formation and transport of MHC class II protein. CD74 is highly expressed in many B-cell malignancies with limited expression in normal tissues (Stein R. et al., CCR 2007). STRO-001 is a no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a83878dc3476fd663109c199e16d8cf1
https://doi.org/10.1158/1538-7445.am2017-67
https://doi.org/10.1158/1538-7445.am2017-67
Autor:
Alice Yam, Ryan Stafford, Maureen Fitch Bruhns, Millicent Embry, Stuart Bussell, Arturo Molina, Trevor J. Hallam, Mark Lupher, Toni Kline, Adam Galan, Shannon Matheny, Michael Brown, Venita DeAlmeida, John F. Boylan, Eric Schwartz, Cristina Abrahams, Jason Kahana, Alexander Steiner, Abigail Yu, Aaron K. Sato, James Zawada, Heather Stephenson, Leo Barnes, Henry Heinsohn, Nicki Vasquez, Rama K. Narla, Heidi Hoffmann, Xiaofan Li
Publikováno v:
Blood. 128:464-464
CD74 is a type II transmembrane glycoprotein involved in the formation and transport of MHC class II protein. High expression of CD74 has been confirmed in follicular lymphoma, diffuse large B-cell lymphoma (DLBCL), chronic lymphocytic leukemia (CLL)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::008142baec3e3dfb7c79e2e10baf02fb
https://doi.org/10.1182/blood.v128.22.464.464
https://doi.org/10.1182/blood.v128.22.464.464
Autor:
Alexander Steiner, Shannon Matheny, John F. Boylan, Ryan Stafford, Heather Stephenson, Cristina Abrahams, Alice Yam, Arturo Molina, Stuart Bussell, Henry Heinsohn, Aaron K. Sato, Maureen Fitch Bruhns, Abigail Yu, Heidi Hoffmann, Adam Galan, Nicki Vasquez, Eric Schwartz, Stellanie Krimm, Venita DeAlmeida, James Zawada, Jason Kahana, Trevor J. Hallam, Mark Lupher, Toni Kline, Rama K. Narla, Xiaofan Li
Publikováno v:
Blood. 128:4465-4465
CD74, also known as HLA-DR-associated invariant chain, is a type II transmembrane glycoprotein highly expressed in many B-cell malignancies. The limited expression of CD74 in normal tissues suggests it may be a suitable ADC target for these tumor typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd745efd1ea7902104bedb9a6ad74e30
https://doi.org/10.1182/blood.v128.22.4465.4465
https://doi.org/10.1182/blood.v128.22.4465.4465
Autor:
Amina Arab, Stuart Bussell, Luis H. Toledo-Pereyra, Peter A. Ward, Jaqueline A. Jordan, Gary Vercruysse, Jeff M. Gauvin, Jack R. Harkema, Gustavo Martínez-Mier
Publikováno v:
Transplantation. 70:1431-1437
Background. The role of nitric oxide in the ischemic injury of the kidney is still controversial. The aim of this study was to reevaluate the beneficial effect of exogenous nitric oxide and define its effects as regulator of gene p53 expression and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e959d23487a13bbb2dff71f21ab3f673
https://doi.org/10.1097/00007890-200011270-00006
https://doi.org/10.1097/00007890-200011270-00006
Autor:
Chun Shen, Zahra Parandoosh, Kimberly D. Victor, Marie Ryder, Stuart Bussell, L. L. Houston, Barbara A. Sosnowski, Ying Buechler
Publikováno v:
European Journal of Biochemistry. 234:706-713
Basic fibroblast growth factor (FGF-2) and saporin were chemically conjugated using the crosslinker, N -succinimidyl-3(2-pyridyldithio)-propionate. When purified, the conjugate was found to be heterogeneous as analyzed by SDS/PAGE, size-exclusion HPL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b1c3bddf445d0b9960f34d01a63eded
https://doi.org/10.1111/j.1432-1033.1995.706_a.x
https://doi.org/10.1111/j.1432-1033.1995.706_a.x
Autor:
Stuart Bussell, Zahra Parandoosh, Barbara A. Sosnowski, L. L. Houston, Michael Ong, Chun Shen, John R. McDonald
Publikováno v:
Protein expression and purification. 8(1)
In order to produce sufficient quantities of fibroblast growth factor-saporin (rFGF-2-SAP) mitotoxin for preclinical evaluation in models of diseases such as cancer and restenosis, we have undertaken the large-scale expression, purification, and char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fe1aae52ec617bbd92efa468846ba2e
https://pubmed.ncbi.nlm.nih.gov/8812840
https://pubmed.ncbi.nlm.nih.gov/8812840
