Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Stuart B. Moss"'
Autor:
John Pywtorak, Greg McCain, Diana L. Blithe, Peter B. Madrid, Subarna Sinha, Merrill Knapp, Toufan Parman, Stuart B. Moss, J Mark Gondek, Min S Lee, Jill Long, Colin VanDervoort, Kenneth Wingerden, Stephen E. Gerrard
Publikováno v:
Biol Reprod
The long and challenging drug development process begins with discovery biology for the selection of an appropriate target for a specific indication. Target is a broad term that can be applied to a range of biological entities such as proteins, genes
Autor:
Stuart B, Moss
Publikováno v:
Biology of reproduction.
Autor:
Marcelle I. Cedars, Lee Warner, Stuart B. Moss, Louis V. DePaolo, Michael L. Eisenberg, Susan E. Taymans
Publikováno v:
Human reproduction open. 2017(2)
STUDY QUESTION: Does the fertility status of an individual act as a biomarker for their future health? SUMMARY ANSWER: Data support an association between reproductive health and overall health for men and women. WHAT IS ALREADY KNOWN: Various chroni
Autor:
Carmen J. Williams, Stuart B. Moss, Esmeralda Rodriguez-Miranda, Kathleen Lin, Mary D. Sammel, George L. Gerton, Scott E. Edwards, Teri Ord, Mariano G. Buffone
Publikováno v:
Biology of Reproduction. 79:164-171
Extracellular adenosine 5 0 -triphosphate (ATPe) treatment of human sperm has been implicated in improving in vitro fertilization (IVF) results. We used the mouse model to investigate mechanisms of action of ATPe on sperm. ATPe treatment significantl
Publikováno v:
Journal of Biological Chemistry. 283:12438-12445
Many candidates have been proposed as zona pellucida-binding proteins. Without precluding a role for any of those candidates, we focused on mouse sperm protein ZP3R/sp56, which is localized in the acrosomal matrix. The objective of this study was to
Autor:
Scott E. Edwards, Stuart B. Moss, Gerald R. Knee, Mariano G. Buffone, George L. Gerton, Stefano Masiero, Sergio Ferasin, Guglielmo Bonanni, Marco Rossato, Carmen J. Williams
Publikováno v:
Reproductive Sciences. 14:655-666
Extracellular adenosine 5'-triphosphate (ATP) previously has been shown to increase the fertilization percentage in human in vitro fertilization (IVF) performed for male factor infertility. The objective of this study is to determine the effects of e
Publikováno v:
Biology of Reproduction. 75:760-766
Male mice deficient for the calmegin (Clgn) or the angiotensin-converting enzyme (Ace) gene show impaired sperm migration into the oviduct and loss of sperm-zona pellucida binding ability in vitro. Since CLGN is a molecular chaperone for membrane tra
Publikováno v:
Biology of Reproduction. 75:492-500
Proper sperm function depends on adequate ATP levels. In the mammalian flagellum, ATP is generated in the midpiece by oxidative respiration and in the principal piece by glycolysis. In locations where ATP is rapidly utilized or produced, adenylate ki
Publikováno v:
Biology of Reproduction. 75:189-196
A-kinase anchor proteins (AKAPs) spatially restrict cAMP-dependent protein kinase by tethering it to various cellular structures. In the polarized sperm cell, various compartmentalized functions, such as motility generated by the flagellum, are modul
Publikováno v:
Molecular & Cellular Proteomics. 5:801-810
The flagellum of a mammalian spermatozoon consists of an axoneme surrounded in distinct regions by accessory structures known as the fibrous sheath, outer dense fibers, and the mitochondrial sheath. Although the characterization of individual protein