Zobrazeno 1 - 10
of 269
pro vyhledávání: '"Stuart A. Johnson"'
Autor:
Carlos Aguilar, Debbie Williams, Ramakrishna Kurapati, Rasneer S. Bains, Philomena Mburu, Andy Parker, Jackie Williams, Danilo Concas, Hilda Tateossian, Andrew R. Haynes, Gareth Banks, Pratik Vikhe, Ines Heise, Marie Hutchison, Gemma Atkins, Simon Gillard, Becky Starbuck, Simona Oliveri, Andrew Blake, Siddharth Sethi, Saumya Kumar, Tanaya Bardhan, Jing-Yi Jeng, Stuart L. Johnson, Lara F. Corns, Walter Marcotti, Michelle Simon, Sara Wells, Paul K. Potter, Heena V. Lad
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110170- (2024)
Summary: Despite some evidence indicating diverse roles of whirlin in neurons, the functional corollary of whirlin gene function and behavior has not been investigated or broadly characterized. A single nucleotide variant was identified from our rece
Externí odkaz:
https://doaj.org/article/8421d27753b841d7bc0fb0382fdbd3c7
Autor:
Adam J. Carlton, Jing-Yi Jeng, Fiorella C. Grandi, Francesca De Faveri, Ana E. Amariutei, Lara De Tomasi, Andrew O’Connor, Stuart L. Johnson, David N. Furness, Steve D.M. Brown, Federico Ceriani, Michael R. Bowl, Mirna Mustapha, Walter Marcotti
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114025- (2024)
Summary: Type I spiral ganglion neurons (SGNs) convey sound information to the central auditory pathway by forming synapses with inner hair cells (IHCs) in the mammalian cochlea. The molecular mechanisms regulating the formation of the post-synaptic
Externí odkaz:
https://doaj.org/article/003f391f46fe499b876a09eda87c4a9d
Publikováno v:
Journal of Functional Biomaterials, Vol 15, Iss 7, p 172 (2024)
Kafirin is an endosperm-specific hydrophobic protein found in sorghum grain and the waste by-product from sorghum biorefineries known as sorghum dried distillers’ grain with solubles (DDGS). Because of kafirin’s poor nutritional profile (negative
Externí odkaz:
https://doaj.org/article/4b20ccd98d5b4866bf0761bc992f3f7e
Autor:
Jing-Yi Jeng, Adam J. Carlton, Richard J. Goodyear, Colbie Chinowsky, Federico Ceriani, Stuart L. Johnson, Tsung-Chang Sung, Yelena Dayn, Guy P. Richardson, Michael R. Bowl, Steve D.M. Brown, Uri Manor, Walter Marcotti
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 26, Iss , Pp 355-370 (2022)
The transduction of acoustic information by hair cells depends upon mechanosensitive stereociliary bundles that project from their apical surface. Mutations or absence of the stereociliary protein EPS8 cause deafness in humans and mice, respectively.
Externí odkaz:
https://doaj.org/article/5942f8bc16104f7a85b0dffab23f1f8b
Autor:
Umar Shah, Deepak Dwivedi, Mark Hackett, Hani Al-Salami, Ranjeet P. Utikar, Chris Blanchard, Adil Gani, Matthew R. Rowles, Stuart K. Johnson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Kafirin, the hydrophobic prolamin storage protein in sorghum grain is enriched when the grain is used for bioethanol production to give dried distillers grain with solubles (DGGS) as a by-product. There is great interest in DDGS kafirin as a
Externí odkaz:
https://doaj.org/article/c525c30427904063b4d88910a5310d91
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
The maintenance of balance and gaze relies on the faithful and rapid signaling of head movements to the brain. In mammals, vestibular organs contain two types of sensory hair cells, type-I and type-II, which convert the head motion-induced movement o
Externí odkaz:
https://doaj.org/article/2aff891aadde429182d17127bd35566d
Autor:
Beatriz Lorente-Cánovas, Stephanie Eckrich, Morag A Lewis, Stuart L Johnson, Walter Marcotti, Karen P Steel
Publikováno v:
PLoS ONE, Vol 17, Iss 3, p e0261530 (2022)
Tasmanian devil (tde) mice are deaf and exhibit circling behaviour. Sensory hair cells of mutants show disorganised hair bundles with abnormally thin stereocilia. The origin of this mutation is the insertion of a transgene which disrupts expression o
Externí odkaz:
https://doaj.org/article/cee86f7ee77649caa32fec15c001cbb2
Autor:
Marco Manca, Piece Yen, Paolo Spaiardi, Giancarlo Russo, Roberta Giunta, Stuart L. Johnson, Walter Marcotti, Sergio Masetto
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Signal transmission by sensory auditory and vestibular hair cells relies upon Ca2+-dependent exocytosis of glutamate. The Ca2+ current in mammalian inner ear hair cells is predominantly carried through CaV1.3 voltage-gated Ca2+ channels. Despite this
Externí odkaz:
https://doaj.org/article/d479e42949604d35a79bf72763bfb463
Autor:
Nasim Rezaee, W.M.A.D. Binosha Fernando, Eugene Hone, Hamid R. Sohrabi, Stuart K. Johnson, Stuart Gunzburg, Ralph N. Martins
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Alzheimer’s disease (AD) is characterized by the excessive deposition of extracellular amyloid-beta peptide (Aβ) and the build-up of intracellular neurofibrillary tangles containing hyperphosphorylated tau proteins. This leads to neuronal damage,
Externí odkaz:
https://doaj.org/article/b4c9189f76bc4059933c26932458e205
Publikováno v:
Foods, Vol 11, Iss 20, p 3244 (2022)
Coffee protein is reported to have high levels of branched-chain amino acids of value in sports nutrition and malnutrition recovery. However, data demonstrating this unusual amino acid composition are limited. We investigated the extraction and isola
Externí odkaz:
https://doaj.org/article/2f880918bf97412388a1329470e047cf