Zobrazeno 1 - 10
of 672 004
pro vyhledávání: '"Stuart A"'
Autor:
Agata N. Makar, Alina Boraman, Peter Mosen, Joanne E. Simpson, Jair Marques, Tim Michelberger, Stuart Aitken, Ann P. Wheeler, Dominic Winter, Alex von Kriegsheim, Noor Gammoh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Autophagy is a finely orchestrated process required for the lysosomal degradation of cytosolic components. The final degradation step is essential for clearing autophagic cargo and recycling macromolecules. Using a CRISPR/Cas9-based screen,
Externí odkaz:
https://doaj.org/article/6883251db50c4cf790616ebe8bd9529f
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract Background Despite Spirochetales being a ubiquitous and medically important order of bacteria infecting both humans and animals, there is extremely limited information regarding their bacteriophages. Of the genus Treponema, there is just a s
Externí odkaz:
https://doaj.org/article/8e27edd0458f4c50a275d1cf68e7669c
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract Protein evolution is constrained by structure and function, creating patterns in residue conservation that are routinely exploited to predict structure and other features. Similar constraints should affect variation across individuals, but i
Externí odkaz:
https://doaj.org/article/0014ad2e277540efa747c99ce87d2b8f
Autor:
Dagmar F Hernandez-Suarez, Kyle Melin, Lorena Gonzalez-Sepulveda, Gualberto Ruaño, Stuart A Scott, Jorge Duconge, Hector J Nuñez-Medina, Mariangeli Monero, Lorna M Torres, Enrique Leal, Ángel M Mayor, Jessicca Y Renta, Edgardo R González-García, Ariel González
Publikováno v:
BMJ Open, Vol 14, Iss 9 (2024)
Objectives To assess whether genotype-guided selection of oral antiplatelet drugs using a clinical decision support (CDS) algorithm reduces the rate of major adverse cardiovascular and cerebrovascular events (MACCEs) among Caribbean Hispanic patients
Externí odkaz:
https://doaj.org/article/7d3cc16172674513a3d950386d0a0bea
Autor:
Rebecca J. Edge, Amy E. Marriott, Emma L. Stars, Rohit N. Patel, Mark C. Wilkinson, Lloyd D.W. King, Julien Slagboom, Choo Hock Tan, Kavi Ratanabanangkoon, Simon J. Draper, Stuart Ainsworth
Publikováno v:
Toxicon: X, Vol 23, Iss , Pp 100204- (2024)
Snakebite is a major global health concern, for which antivenom remains the only approved treatment to neutralise the harmful effects of the toxins. However, some medically important toxins are poorly immunogenic, resulting in reduced efficacy of the
Externí odkaz:
https://doaj.org/article/7786c6bea5b54487a9ec625049f911c8
Autor:
Justyna Bartoszko, Sarah Miles, Saba Ansari, Deep Grewal, Michelle Li, Jeannie Callum, Stuart A. McCluskey, Yulia Lin, Keyvan Karkouti
Publikováno v:
BJA Open, Vol 11, Iss , Pp 100303- (2024)
Background: Iron-deficiency anaemia, occurring in 30–40% of patients undergoing cardiac surgery, is an independent risk factor for adverse outcomes. Our long-term goal is to assess if postoperative i.v. iron therapy improves clinical outcomes in pa
Externí odkaz:
https://doaj.org/article/66e122d56bd74f058c52041362d186c7
Publikováno v:
The Lancet Regional Health. Americas, Vol 36, Iss , Pp 100851- (2024)
Externí odkaz:
https://doaj.org/article/4e68b741f46644be9f6f8efaf3006c1f
Autor:
Swagata Ghatak, Jolene K. Diedrich, Maria Talantova, Nivedita Bhadra, Henry Scott, Meetal Sharma, Matthew Albertolle, Nicholas J. Schork, John R. Yates III, Stuart A. Lipton
Publikováno v:
Advanced Science, Vol 11, Iss 29, Pp n/a-n/a (2024)
Abstract Standard single‐cell (sc) proteomics of disease states inferred from multicellular organs or organoids cannot currently be related to single‐cell physiology. Here, a scPatch‐Clamp/Proteomics platform is developed on single neurons gene
Externí odkaz:
https://doaj.org/article/7f4dd02cff274168ba32976ec18c4157
Autor:
Joanne Spetz, Johnie Rose, James G. Kahn, Tracy Lin, Douglas Levy, Oksana Pugach, Susan Hyde, Belinda Borrelli, Michelle Henshaw, Molly Martin, Suchitra Nelson, Francisco Ramos-Gomez, Stuart A. Gansky
Publikováno v:
Frontiers in Oral Health, Vol 5 (2024)
IntroductionIn 2015, the National Institute of Dental and Craniofacial Research (NIDCR) launched the Multidisciplinary Collaborative Research Consortium to Reduce Oral Health Disparities in Children, supporting four randomized trials testing strategi
Externí odkaz:
https://doaj.org/article/38d45387ea384bf696133279474cc6bd
Autor:
Christos Georgiadis, Lauren Nickolay, Farhatullah Syed, Hong Zhan, Soragia Athina Gkazi, Annie Etuk, Ulrike Abramowski-Mock, Roland Preece, Piotr Cuber, Stuart Adams, Giorgio Ottaviano, Waseem Qasim
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Umbilical cord blood (UCB) T cells exhibit distinct naive ontogenetic profiles and may be an attractive source of starting cells for the production of chimeric antigen receptor (CAR) T cells. Pre-selection of UCB-T cells on the basis of CD62L express
Externí odkaz:
https://doaj.org/article/cdb82ae8baf04b8389ea2a1288375c7b