Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Stuart, Schnitt"'
Autor:
Felipe Batalini, Doga C. Gulhan, Xanthi Lida Katopodi, Nikolas Kalavros, Antuan Tran, Dimitra Karagkouni, Emily Stern-Gatof, Stuart Schnitt, Judy E. Garber, Gerburg M. Wulf, Peter J. Park, Ioannis Vlachos, Nadine Tung
Publikováno v:
Cancer Research. 83:P5-12
Background Breast cancers in women with a germline BRCA1/2 mutation (gBRCAm) have homologous recombination deficiency (HRD) and are sensitive to therapies causing double-strand DNA breaks. In TBCRC 031 (INFORM), both neoadjuvant cisplatin and doxorub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::225c6bbf0d4d72b8011aead8cfde79c6
https://doi.org/10.1158/1538-7445.sabcs22-p5-12-03
https://doi.org/10.1158/1538-7445.sabcs22-p5-12-03
Autor:
Ana C Garrido-Castro, Noah Graham, Kevin Bi, Jihye Park, Jingxin Fu, Tanya Keenan, Edward Thomas Richardson, Ricardo Pastorello, Paulina Lange, Victoria Attaya, Robert Wesolowski, Natalie Sinclair, Zarah Lucas, Steve Lo, Nadine Tung, Meredith Faggen, Peter A Kaufman, Caroline C Block, Fred Briccetti, Madhavi Toke, Wendy Chen, Kai Wucherpfennig, Sascha Marx, Ye Tian, Judith Agudo, Jennifer L Guerriero, Stuart Schnitt, Nancy U Lin, Eric P Winer, Elizabeth A Mittendorf, Nabihah Tayob, Eliezer Van Allen, Sara M Tolaney
Publikováno v:
Cancer Research. 82:P2-14
Background: Platinum agents induce DNA crosslinking and cause accumulation of genotoxic stress, which leads to immune activation via IFN-γ signaling, making the combination with nivolumab (PD-1 antibody) an attractive strategy to enhance the benefit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab06b6799048f3fc518e72aa6d5cdcb6
https://doi.org/10.1158/1538-7445.sabcs21-p2-14-18
https://doi.org/10.1158/1538-7445.sabcs21-p2-14-18
Autor:
Rulla M. Tamimi, Walter C. Willett, Karin B. Michels, A. Heather Eliassen, Bernard Rosner, Stuart Schnitt, Andrew H. Beck, Laura C. Collins, Rong Hu, Erica T. Warner
Height and body size in childhood and young adulthood have been consistently associated with breast cancer risk; whether associations differ across molecular subtypes is unclear. In a pooled analysis of the Nurses' Health Studies, we prospectively ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05eac845c147fbfb57369e33af1c2da9
https://doi.org/10.1158/1940-6207.c.6547357
https://doi.org/10.1158/1940-6207.c.6547357
Autor:
Rulla M. Tamimi, Walter C. Willett, Karin B. Michels, A. Heather Eliassen, Bernard Rosner, Stuart Schnitt, Andrew H. Beck, Laura C. Collins, Rong Hu, Erica T. Warner
Tables 1 and 2 display estimates for height, BMI at age 18 and somatotypes for pre and postmenopausal women. Table 3 contains estimates for triple negative tumors for all four exposures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::401278a2282e247c6afe5813d25b82f5
https://doi.org/10.1158/1940-6207.22534039.v1
https://doi.org/10.1158/1940-6207.22534039.v1
Autor:
Vincent A. Miller, Myles Brown, Philip Stephens, Lajos Pusztai, Steven E. Come, Stuart Schnitt, Lauren Gilmore, Tamar Rubinek, Ido Wolf, Lior Soussan-Gutman, Addie Dvir, Jeffrey S. Ross, Geoff Otto, Doron Lipson, Matthew Hawryluk, James Sun, Mirna Jarosz, Maureen T. Cronin, Justin M. Balko, Jennifer Giltnane, Carlos L. Arteaga, Henry Gómez, Massimo Cristofanilli, Jose A. Perez-Fidalgo, Jaime Ferrer-Lozano, Ana Maria Gonzalez-Angulo, Funda Meric-Bernstam, Garrett Frampton, Gilles Buchwalter, Roman Yelensky, Rinath Jeselsohn
Purpose: We undertook this study to determine the prevalence of estrogen receptor (ER) α (ESR1) mutations throughout the natural history of hormone-dependent breast cancer and to delineate the functional roles of the most commonly detected alteratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06acf2bac7a2e8a9a46fc8d4602eef28
https://doi.org/10.1158/1078-0432.c.6522539.v1
https://doi.org/10.1158/1078-0432.c.6522539.v1
Autor:
Vincent A. Miller, Myles Brown, Philip Stephens, Lajos Pusztai, Steven E. Come, Stuart Schnitt, Lauren Gilmore, Tamar Rubinek, Ido Wolf, Lior Soussan-Gutman, Addie Dvir, Jeffrey S. Ross, Geoff Otto, Doron Lipson, Matthew Hawryluk, James Sun, Mirna Jarosz, Maureen T. Cronin, Justin M. Balko, Jennifer Giltnane, Carlos L. Arteaga, Henry Gómez, Massimo Cristofanilli, Jose A. Perez-Fidalgo, Jaime Ferrer-Lozano, Ana Maria Gonzalez-Angulo, Funda Meric-Bernstam, Garrett Frampton, Gilles Buchwalter, Roman Yelensky, Rinath Jeselsohn
PDF file - 187K, Supplementary Table 1: Detailed demographic information of all patients with metastatic breast cancer, including cohorts LM+ and EM+. Supplementary Table 2: ESR1 variant sequence data details. Abbreviations: cvg, coverage, N/A, non-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::364bdf44a49cc770d75e9442bdc0d36b
https://doi.org/10.1158/1078-0432.22452653
https://doi.org/10.1158/1078-0432.22452653
Autor:
Vincent A. Miller, Myles Brown, Philip Stephens, Lajos Pusztai, Steven E. Come, Stuart Schnitt, Lauren Gilmore, Tamar Rubinek, Ido Wolf, Lior Soussan-Gutman, Addie Dvir, Jeffrey S. Ross, Geoff Otto, Doron Lipson, Matthew Hawryluk, James Sun, Mirna Jarosz, Maureen T. Cronin, Justin M. Balko, Jennifer Giltnane, Carlos L. Arteaga, Henry Gómez, Massimo Cristofanilli, Jose A. Perez-Fidalgo, Jaime Ferrer-Lozano, Ana Maria Gonzalez-Angulo, Funda Meric-Bernstam, Garrett Frampton, Gilles Buchwalter, Roman Yelensky, Rinath Jeselsohn
XLSX file - 122K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06fca6683790241c0dad42aa1f4b293c
https://doi.org/10.1158/1078-0432.22452656.v1
https://doi.org/10.1158/1078-0432.22452656.v1
Autor:
Rachel Factor, Stuart Schnitt, Robert West, Terry Hyslop, Thomas Lynch, Deborah Collyar, Desiree Basila, Lars Grimm, Lorraine King, Jeffrey Marks, Sunil Badve, Mark Watson, Marc Ryser, Anna Weiss, Anna Rapperport, Linda McCall, H. T. Carisa Le-Petross, Ann Partridge, E Shelley Hwang, Alastair M. Thompson
Publikováno v:
Cancer Research. 83:P6-04
Introduction COMET (Comparing an Operation to Monitoring, with or without Endocrine Therapy) is a phase III clinical trial randomizing patients diagnosed with low-intermediate grade DCIS to either active monitoring or surgery. The study has a planned
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92311627aa464d0ebe17f0bf3e096839
https://doi.org/10.1158/1538-7445.sabcs22-p6-04-13
https://doi.org/10.1158/1538-7445.sabcs22-p6-04-13
Autor:
Tan H. Nguyen, Mohammad Mirzadeh, Aaditya Prakash, Emma L. Krause, Jun Zhang, Michael Pyle, Esther R. Ogayo, Harry C. Cramer, Busem Binboga Kurt, Jacqueline Brosnan-Cashman, Michael G. Drage, Stuart Schnitt, Andrew H. Beck, Michael Montalto, Ilan Wapinski, Laura Chambre, Sara Tolaney, Adrienne Waks, Justin Lee, Elizabeth A. Mittendorf
Publikováno v:
Cancer Research. 83:P5-02
Background: Neoadjuvant treatment (NAT) combining chemotherapy and HER2-targeted agents is frequently administered to HER2-positive (HER2+) breast cancer (BC) patients, with some experiencing a pathological complete response (pCR) and others having r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a73789b0b431359a5a454b69feaab2e
https://doi.org/10.1158/1538-7445.sabcs22-p5-02-09
https://doi.org/10.1158/1538-7445.sabcs22-p5-02-09
Autor:
Shom Goel, Heather Ann Brauer, Yuqi Ren, Kara Gorman, Wafa Osmani, Jessica Pittenger, Chelsea Andrews, Edward T Richardson, Elizabeth A Mittendorf, MD PhD, Eric P Winer, Stuart Schnitt, Sara M Tolaney
Publikováno v:
Cancer Research. 80:P4-06
Introduction: TNBCs show marked heterogeneity in their spectrum of genomic alterations, patterns of gene expression, proteomic profiles, and immune microenvironments. Although TNBC heterogeneity has been characterized at each of these levels individu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f8a5c476a4eb628374323ecfb0fb0b5
https://doi.org/10.1158/1538-7445.sabcs19-p4-06-01
https://doi.org/10.1158/1538-7445.sabcs19-p4-06-01