Comparative Analysis and Ancestral Sequence Reconstruction of Bacterial Sortase Family Proteins Generates Functional Ancestral Mutants with Different Sequence Specificities.

Autor: Valgardson, Jordan D.¹ jvalgard@stanford.edu, Struyvenberg, Sarah A.¹ sastruyvenberg@msn.com, Sailer, Zachary R.^2,3 zachsailer@gmail.com, Piper, Isabel M.¹ isabel_piper@berkeley.edu, Svendsen, Justin E.^1,2 harms@uoregon.edu, Johnson, D. Alex¹ dajohnso@caltech.edu, Vogel, Brandon A.¹ vogelb2@wwu.edu, Antos, John M.¹ antosj@wwu.edu, Harms, Michael J.^2,3, Amacher, Jeanine F.¹ amachej@wwu.edu

Publikováno v: Bacteria (2674-1334). Jun2022, Vol. 1 Issue 2, p121-135. 15p.

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Additive energetic contributions of multiple peptide positions determine the relative promiscuity of viral and human sequences for PDZ domain targets.

Autor: Tahti EF; Department of Chemistry, Western Washington University, Bellingham, WA, USA., Blount JM; Department of Chemistry, Western Washington University, Bellingham, WA, USA., Jackson SN; Department of Chemistry, Western Washington University, Bellingham, WA, USA., Gao M; Department of Chemistry, Western Washington University, Bellingham, WA, USA., Gill NP; Department of Biochemistry, Geisel School of Medicine at Dartmouth, Hanover, NH, USA., Smith SN; Department of Chemistry, Western Washington University, Bellingham, WA, USA., Pederson NJ; Department of Chemistry, Western Washington University, Bellingham, WA, USA., Rumph SN; Department of Biochemistry, Bowdoin College, Brunswick, ME, USA., Struyvenberg SA; Department of Chemistry, Western Washington University, Bellingham, WA, USA., Mackley IGP; Department of Chemistry, Western Washington University, Bellingham, WA, USA., Madden DR; Department of Biochemistry, Geisel School of Medicine at Dartmouth, Hanover, NH, USA., Amacher JF; Department of Chemistry, Western Washington University, Bellingham, WA, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Jan 10. Date of Electronic Publication: 2023 Jan 10.