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Development and Validation of a New Storage Procedure to Extend the In-Use Stability of Azacitidine in Pharmaceutical Formulations

Autor: Iudicello, A., Genovese, F., Strusi, V., Dominici, M., Ruozi, B.

Publikováno v: Pharmaceuticals
Volume 14
Issue 9
Pharmaceuticals, Vol 14, Iss 943, p 943 (2021)

Stability studies performed by the pharmaceutical industry are principally designed to fulfill licensing requirements. Thus, post-dilution or post-reconstitution stability data are frequently limited to 24 h only for bacteriological reasons, regardle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fbef5b579f051f95475046d6b5b9379a

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Identification of putative adult stem cells in the rat thyroid and their use in ex situ bioengineering

Autor: Strusi, V., Zini, N., Mastrogiacomo, S., Zamparelli, A., Barbaro, F., Dallatana, D., Parrilli, A., Giardino, R., Toni, R.

Adult stem cells have been recently isolated from the human and mouse thyroid. Identification has been possible by their capacity to form floating cell spheroids or thyrospheres when primary cells are cultured in the absence of serum but presence of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::82d6a5c1032de9ceb9d85aa9e456f687

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Gli organi endocrini bioartificiali: prospettive della ricerca traslazionale applicata alla medicina rigenerativa in endocrinologia

Autor: Strusi, V, Mastrogiacomo, S, Zini, N, Dallatana, D, Spaletta, G, Bassoli, E, Gatto, A, Zamparelli, A, Lippi, Giuseppe, Iafisco, M, Sandri, M, Tampieri, A, Toni, R.

Ricostruire in laboratorio, ossia ex situ, ghiandole endocrine bioartificiali è una prospettiva innovativa della ricerca traslazionale applicata alla medicina rigenerativa dei disturbi endocrino-metabolici. Utilizzando cellule staminali o primarie �

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d0d91de877f196cd39a54805ea5f4b03
http://hdl.handle.net/11585/125287

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BIOENGINEERING OF THE THYROID LOBE: USE OF ITS STROMAL / VASCULAR MATRIX AS A SCAFFOLD FOR EX SITU RECONSTRUCTION

Autor: Toni, R., Strusi, V., Zini, N., Dallatana, D., Mastrogiacomo, S., Parrilli, A., Giardino, R., Lippi, G., Spaletta, G., Bassoli, Elena, Gatto, Andrea, Iafisco, M., Sandri, M., Tampieri, A.

Regenerative medicine of endocrine glands is one of the newest fields in biomedical research, and promises to become a primary strategy to treat a number of endocrine disorders. Using computational bioengineering we have recently suggested that the t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::95d7954d577d872e1d8aa3f0ec7a3129
http://hdl.handle.net/11585/125296

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A combined Additive Layer Manufacturing / Indirect Replication method to prototype 3D vascular-like structures of soft tissue and endocrine organs

Autor: Bassoli, Elena, Denti, Lucia, Gatto, Andrea, Spaletta, G., Paderno, A., Zini, N., Parrilli, A., Giardino, R., Strusi, V., Dallatana, D., Mastrogiacomo, S., Zamparelli, A., Iafisco, M., Toni, R.

We describe an innovative methodology combining Additive Layer Manufacturing (ALM) and indirect replication to reconstruct reticular-like, three-dimensional (3D) structures mimicking the vascular network of soft tissue and endocrine organs. Using a f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::418ff80795a58ab8910e0a4209e70585
http://hdl.handle.net/11585/121743

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Poly-L-lactic acid and poly-e-caprolactone as biomaterials for ex-situ bioengineering of the rat thyroid tissue

Autor: Mastrogiacomo, S., Strusi, V., Dallatana, D., Barbaro, F., Zini, N., Zamparelli, A., Iafisco, M., Parrilli, A., Giardino, R., Lippi, G., Spaletta, G., Bassoli, E., Gatto, A., Sandri, M., Sprio, S., Tampieri, A., Toni, R.

We are currently developing innovative methodologies for rapid prototyping of threedimensional (3D) replicas of the vascular matrix of soft and hard tissue organs, primarily the thyroid and bones, with the intent of obtaining organomorphic scaffolds

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34b5901d2a5d140d8befb3e47693eb8f
http://hdl.handle.net/11585/125298

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Ex situ bioengineering of the rat thyroid using as a scaffold the three-dimensional (3D) decellularized matrix of the glandular lobe: clues to the organomorphic principle

Autor: Strusi, V., Zini, N., Dallatana, D., Parrilli, A., Giardino, R., Lippi, G., Spaletta, G., Bassoli, E., Gatto, A., Iafisco, M., Sandri, M., Tampieri, A., Toni, R.

Recently, we designed a bioreactor system for bioengineering ex situ (i.e. on the laboratory bench) a bioartificial thyroid gland suitable for transplantation. It is based on the organomorphic principle, i.e. the bioreactor mimics the macro-microscop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::52ac61b1318e8d02fc0d02b9e19f06a5

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Akademický článek

A combined additive layer manufacturing / indirect replication method to prototype 3D vascular-like structures of soft tissue and endocrine organs.

Autor: Bassoli, E., Denti, L., Gatto, A., Spaletta, G., Paderno, A., Zini, N., Parrilli, A., Giardino, R., Strusi, V., Dallatana, D., Mastrogiacomo, S., Zamparelli, A., Iafisco, M., Toni, R.

Publikováno v: Virtual & Physical Prototyping; Mar2012, Vol. 7 Issue 1, p3-11, 9p, 10 Color Photographs, 1 Black and White Photograph, 2 Charts

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