Zobrazeno 1 - 10
of 266
pro vyhledávání: '"Strukova SM"'
Publikováno v:
Biochemistry (Moscow). 82:778-790
Key hemostatic serine proteases such as thrombin and activated protein C (APC) are signaling molecules controlling blood coagulation and inflammation, tissue regeneration, neurodegeneration, and some other processes. By interacting with protease-acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f18cf669ffd21b53c63a5b16d4e50c1
https://doi.org/10.1134/s0006297917070033
https://doi.org/10.1134/s0006297917070033
Publikováno v:
Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology. 10:126-134
The present study focuses on possible ways to protect brain neurons during neuroinflammation. For the first time it is shown that peptide NPNDKYEPF amide, similar to activated protein C (APC), protects hippocampal neurons in a model of neuroinflammat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39fd832d17419523818bf9331d252fb6
https://doi.org/10.1134/s1990747816010037
https://doi.org/10.1134/s1990747816010037
Publikováno v:
Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology. 8:50-59
Protein C anticoagulant system is a multifunctional cofactor-dependent system. In addition to anticoagulant function, activated protein C (APC) also exhibits neuroprotective activity in hypoxia and stroke, but there are no data on potential effects o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcc6b5df7b6817629df63a68076f9f0b
https://doi.org/10.1134/s1990747813050048
https://doi.org/10.1134/s1990747813050048
Publikováno v:
Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology. 8:116-120
Haemostatic proteinases may appear in brain tissue after injury and under inflammation as a result of the blood-brain barrier disruption. Serine proteinases regulate cell functions through G-protein-coupled transmembrane protease-activated receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::373eb03f01b55555d07b55a731f90247
https://doi.org/10.1134/s1990747813050176
https://doi.org/10.1134/s1990747813050176
Publikováno v:
Neurochemistry International. 63:101-111
The transcription factor NF-κB regulates the expression of multiple genes involved in inflammation, apoptotic cell death and cell survival. We previously demonstrated that activated protein C (APC), a serine protease of hemostasis with anticoagulant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb5aa2af6c097cac1245f11fa338167
https://doi.org/10.1016/j.neuint.2013.05.008
https://doi.org/10.1016/j.neuint.2013.05.008
Publikováno v:
Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology. 6:56-66
Activated protein C (APC) is one of the key proteinases of hemostasis exhibiting anti-coagulant, anti-inflammatory, and protective functions. In the present work, the anti-apoptotic effect of the proteinase on the glutamate toxicity model in cultured
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e83a4a5bb7d61afe0d07b1059bca8756
https://doi.org/10.1134/s1990747811060067
https://doi.org/10.1134/s1990747811060067
Autor:
Georg Reiser, Pinelis Vg, L. R. Gorbacheva, Olga Davidova, Shin'ichi Ishiwata, Elena Sokolova, Strukova Sm
Publikováno v:
Journal of Neurochemistry. 111:967-975
Activated protein C (APC) is an anticoagulant and anti-inflammatory factor that acts via endothelial protein C receptor (EPCR). Interestingly, APC also exhibits neuroprotective activities. In the present study, we demonstrate for the first time expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d16154a997420a816e7b2f491f9d1955
https://doi.org/10.1111/j.1471-4159.2009.06380.x
https://doi.org/10.1111/j.1471-4159.2009.06380.x
Autor:
Strukova Sm, B. M. Feldman, Gleb B. Sukhorukov, T. V. Vasil’eva, S. M. Kunizhev, G. N. Vorozhtsov, Lev D. Rumsh, A. V. Rusanova, Elena Markvicheva, Tatiana Borodina
Publikováno v:
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry. 2:176-182
The microcapsules with entrapped herbal water-soluble extracts of plantain Plantago major and calendula Calendula officinalis L. (PCE) were prepared by layer-by-layer (LbL)-adsorption of carrageenan and oligochitosan onto CaCO 3 microparticles with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59bd72a8e54bede251748e77ac173180
https://doi.org/10.1134/s199075080802008x
https://doi.org/10.1134/s199075080802008x
Autor:
A. V. Rusanova, Grandfis K, A. M. Makarova, L. R. Gorbacheva, Stashevskaia Ks, Strukova Sm, Elena Markvicheva, I. A. Prudchenko, Vitaly P. Zubov
Publikováno v:
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry. 1:147-154
Thrombin receptor agonist peptide (TRAP-6) may be successfully used instead of thrombin to stimulate regeneration of damaged tissues. Thrombin application is limited by its high price, instability, and proin-flammatory effect at high concentrations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e34f01da8635b74d39e3789342e413f1
https://doi.org/10.1134/s1990750807020072
https://doi.org/10.1134/s1990750807020072
Publikováno v:
Biomeditsinskaia khimiia. 60(6)
Activated protein C (APC) is serine protease hemostasis, independent of its anticoagulant activity, exhibits anti-inflammatory and anti-apoptotic properties that determine the possibility of the protective effects of APC in different diseases, includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2db471fcb802420fe69681d422ed4749
https://pubmed.ncbi.nlm.nih.gov/25552512
https://pubmed.ncbi.nlm.nih.gov/25552512