Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Structural biochemistry"'
Publikováno v:
Applied Medical Informatics, Vol 45, Iss Suppl. S1, Pp S41-S41 (2023)
Benzodiazepines are a type of psychotropic drugs with tranquilizing effect, originally used as ansiolytics. However, benzodiazepines are highly addictive, and a person who abuses them faces a host of symptoms. Moreover, the market for new psychoactiv
Externí odkaz:
https://doaj.org/article/c9470a82f9ef4b84a952812e940cbf47
Akademický článek
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Autor:
Mark A. Wilson, Bryan J. Leong, Ulschan Bathe, Christopher S. Henry, Paul E. Abraham, Andrew D. Hanson, Donald R. McCarty
Publikováno v:
Biochemistry. 60:3555-3565
Enzymes have in vivo life spans. Analysis of life spans, i.e., lifetime totals of catalytic turnovers, suggests that nonsurvivable collateral chemical damage from the very reactions that enzymes catalyze is a common but underdiagnosed cause of enzyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffbbd94f4a9cae0ba7106688fab271bc
https://doi.org/10.1021/acs.biochem.1c00613
https://doi.org/10.1021/acs.biochem.1c00613
Autor:
Andras Szollosi
Publikováno v:
Life, Vol 11, Iss 397, p 397 (2021)
Life
Life
The transient receptor potential melastatin (TRPM) family belongs to the superfamily of TRP ion channels. It consists of eight family members that are involved in a plethora of cellular functions. TRPM2 is a homotetrameric Ca2+-permeable cation chann
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2f2585188ef06ab864845220a6f4261
https://www.mdpi.com/2075-1729/11/5/397
https://www.mdpi.com/2075-1729/11/5/397
Autor:
Wyatt W. Yue
Publikováno v:
Biochimie. 183
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af937037ada7ddab889ee18cd6ad8f00
https://pubmed.ncbi.nlm.nih.gov/33636250
https://pubmed.ncbi.nlm.nih.gov/33636250
Akademický článek
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Autor:
Nicholas G Economos, W. Mark Saltzman, Peter M. Glazer, Stanley Oyaghire, Elias Quijano, Adele S. Ricciardi
Publikováno v:
Molecules
Molecules, Vol 25, Iss 3, p 735 (2020)
Molecules, Vol 25, Iss 3, p 735 (2020)
Unusual nucleic acid structures are salient triggers of endogenous repair and can occur in sequence-specific contexts. Peptide nucleic acids (PNAs) rely on these principles to achieve non-enzymatic gene editing. By forming high-affinity heterotriplex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efe71b40f739c8a4667e31d6762c829f
https://pubmed.ncbi.nlm.nih.gov/32046275
https://pubmed.ncbi.nlm.nih.gov/32046275
Publikováno v:
MedChemComm. 9:1093-1104
Skp2 is a member of the F-box family of proteins that serve as substrate-specific adaptors in Skp1–CUL1–ROC1–F-box (SCF) E3 ubiquitin ligases. Skp2 (Fbxl1) directly binds to the tumor suppressor p27 in the context of the SCF(Skp2) E3 ubiquitin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beaf1886c30a95430e8dc0d8a1ce10eb
https://doi.org/10.1039/c8md00140e
https://doi.org/10.1039/c8md00140e
Publikováno v:
Membranes
Membranes, Vol 11, Iss 683, p 683 (2021)
Membranes, Vol 11, Iss 683, p 683 (2021)
Precise characterization of biomolecular information such as molecular structures or intermolecular interactions provides essential mechanistic insights into the understanding of biochemical processes. As the resolution of imaging-based measurement t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1eb25035429f354eddf8a63dd1621ed
https://doi.org/10.3390/membranes11090683
https://doi.org/10.3390/membranes11090683
Autor:
Janis E. Lochner
Publikováno v:
The FASEB Journal. 33
Macromolecular structure, interactions and dynamics are essential underpinnings of an education in biochemistry. Biochemists often convey these core concepts by systematically probing the structure...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ece10bea7b47fd5b3a57363f278a78fc
https://doi.org/10.1096/fasebj.2019.33.1_supplement.617.20
https://doi.org/10.1096/fasebj.2019.33.1_supplement.617.20