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MA04.05 P53 Non-Disruptive Mutation is a Negative Predictive Factor for OS and PFS in EGFR M+ NSCLC Treated with TKI

Autor: Roeper, Julia, Netchaeva, Maria, Lueers, Anne, Regina, Prenzel, Sriba, Douglas, Willborn, Kay, Stropiep, Ursula, Hallas, Cora, Tiemann, Markus, Neemann, Nicole, Heukamp, Lukas, Griesinger, Frank, Falk, Markus

Publikováno v: In Journal of Thoracic Oncology January 2017 12(1) Supplement:S359-S360

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TP53 co-mutations in EGFR mutated patients in NSCLC stage IV: A strong predictive factor of ORR, PFS and OS in EGFR mt+ NSCLC.

Autor: Roeper J; Department of Internal Medicine-Oncology, Carl v. Ossietzky University of Oldenburg, Oldenburg, Germany.; Department of Hematology and Oncology, Pius-Hospital, Oldenburg, Germany.; Lung Cancer Network NOWEL.org, Oldenburg, Germany., Falk M; Institute of Hematopathology Hamburg, Hamburg, Germany.; Lung Cancer Network NOWEL.org, Oldenburg, Germany., Chalaris-Rißmann A; Institute of Hematopathology Hamburg, Hamburg, Germany.; Lung Cancer Network NOWEL.org, Oldenburg, Germany., Lueers AC; Department of Internal Medicine-Oncology, Carl v. Ossietzky University of Oldenburg, Oldenburg, Germany.; Department of Hematology and Oncology, Pius-Hospital, Oldenburg, Germany., Ramdani H; Department of Internal Medicine-Oncology, Carl v. Ossietzky University of Oldenburg, Oldenburg, Germany.; Department of Hematology and Oncology, Pius-Hospital, Oldenburg, Germany.; Lung Cancer Network NOWEL.org, Oldenburg, Germany., Wedeken K; Department of Tumor Documentation, Cancer Center Oldenburg, Pius Hospital Oldenburg, Oldenburg, Germany., Stropiep U; Department of Hematology and Oncology, Pius-Hospital, Oldenburg, Germany.; Lung Cancer Network NOWEL.org, Oldenburg, Germany., Diehl L; Institute of Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Tiemann M; Institute of Hematopathology Hamburg, Hamburg, Germany.; Lung Cancer Network NOWEL.org, Oldenburg, Germany., Heukamp LC; Institute of Hematopathology Hamburg, Hamburg, Germany.; Lung Cancer Network NOWEL.org, Oldenburg, Germany., Otto-Sobotka F; Division of Epidemiology and Biometry, Carl v. Ossietzky University of Oldenburg, Oldenburg, Germany., Griesinger F; Department of Internal Medicine-Oncology, Carl v. Ossietzky University of Oldenburg, Oldenburg, Germany.; Department of Hematology and Oncology, Pius-Hospital, Oldenburg, Germany.; Lung Cancer Network NOWEL.org, Oldenburg, Germany.

Publikováno v: Oncotarget [Oncotarget] 2020 Jan 21; Vol. 11 (3), pp. 250-264. Date of Electronic Publication: 2020 Jan 21 (Print Publication: 2020).