Sensitive detection of squamous cells in bone marrow and blood of head and neck cancer patients by E48 reverse transcriptase-polymerase chain reaction

Autor: Brakenhoff, Ruud H., Stroomer, Joep G.W., Ten Brink, Corlinda, De Bree, Remco, Weima, Sjerp M., Snow, Gordon B., Van Dongen, Guus A.M.S.

Publikováno v: Clinical Cancer Research, 5(4), 725-732. American Association for Cancer Research Inc.
Brakenhoff, R H, Stroomer, J G W, Ten Brink, C, De Bree, R, Weima, S M, Snow, G B & Van Dongen, G A M S 1999, ' Sensitive detection of squamous cells in bone marrow and blood of head and neck cancer patients by E48 reverse transcriptase-polymerase chain reaction ', Clinical Cancer Research, vol. 5, no. 4, pp. 725-732 .

In previous studies, we described the selective reactivity of monoclonal antibody E48 with normal squamous and transitional epithelia and their malignant counterparts and the capacity of monoclonal antibody E48 for selective tumor targeting in head a

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