Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Stromatoxin"'
Publikováno v:
The Journal of physiology. 597(14)
Key points Kv2 currents maintain and regulate motoneuron (MN) repetitive firing properties. Kv2.1 channel clustering properties are dynamic and respond to both high and low activity conditions. The enzyme calcineurin regulates Kv2.1 ion channel declu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f26a2d33650dae768974c73bb6f00d6e
https://pubmed.ncbi.nlm.nih.gov/31145471
https://pubmed.ncbi.nlm.nih.gov/31145471
Autor:
Samantha J. Fromme, Robert H. Cox
Publikováno v:
Cell Biochemistry and Biophysics. 74:499-511
We have shown that three components contribute to functional voltage gated K+ (K v) currents in rat small mesenteric artery myocytes: (1) Kv1.2 plus Kv1.5 with Kvβ1.2 subunits, (2) Kv2.1 probably associated with Kv9.3 subunits, and (3) Kv7.4 subunit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::797b58483f37905e6875b94fb65b7ddb
https://doi.org/10.1007/s12013-016-0763-4
https://doi.org/10.1007/s12013-016-0763-4
Autor:
Robert H. Cox, Samantha J. Fromme
Publikováno v:
Cell Biochemistry and Biophysics. 74:263-276
Multiple K v channel complexes contribute to total K v current in numerous cell types and usually subserve different physiological functions. Identifying the complete compliment of functional K v channel subunits in cells is a prerequisite to underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c751588ded261e7286ca08ef0d5c7c
https://doi.org/10.1007/s12013-015-0715-4
https://doi.org/10.1007/s12013-015-0715-4
Autor:
Munenori Kusunoki, Kiichi Hirota, Tomohiro Shoji, Takeo Uba, Yoshiyuki Matsuo, Hiromasa Tanaka, Mikio Hayashi, Chisato Sumi
Publikováno v:
PeerJ, Vol 7, p e8157 (2019)
BackgroundProper glycemic control is an important goal of critical care medicine, including perioperative patient care that can influence patients’ prognosis. Insulin secretion from pancreatic β-cells is generally assumed to play a critical role i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40549585f86e51677b4ae20be4219a14
https://doi.org/10.7717/peerj.8157
https://doi.org/10.7717/peerj.8157
Autor:
William C. Cole, Emma J. Walsh, Ahmed F. El-Yazbi, Chiu-Hsiang Liao, Khaled S. Abd-Elrahman, Xi Zoë Zhong, Michael P. Walsh
Publikováno v:
The Journal of Physiology. 588:4519-4537
Cerebral vascular smooth muscle contractility plays a crucial role in controlling arterial diameter and, thereby, blood flow regulation in the brain. A number of K+ channels have been suggested to contribute to the regulation of diameter by controlli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb0df048a802c223f081be1fe26f7612
https://doi.org/10.1113/jphysiol.2010.196618
https://doi.org/10.1113/jphysiol.2010.196618
Publikováno v:
Acta Physiologica. 225:e13176
Aim Potassium channels are key regulators of smooth muscle membrane potential and arterial tone. However, the roles of potassium channels in vascular tone regulation in the systemic circulation during early postnatal development are poorly understood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c04f835b543d9f1d93e14d50336555a
https://doi.org/10.1111/apha.13176
https://doi.org/10.1111/apha.13176
Autor:
William C. Cole, Iain A. Greenwood, Susumu Ohya, James D. Moffatt, Xi Zoë Zhong, Søren Peter Olesen, Maksym I. Harhun
Publikováno v:
The Journal of Physiology. 588:3277-3293
KCNQ gene expression was previously shown in various rodent blood vessels, where the products of KCNQ4 and KCNQ5, Kv7.4 and Kv7.5 potassium channel subunits, respectively, have an influence on vascular reactivity. The aim of this study was to determi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1155408b8508eb62e63851ba1663ab5
https://doi.org/10.1113/jphysiol.2010.192823
https://doi.org/10.1113/jphysiol.2010.192823
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 299:R177-R184
Members of the voltage-gated K+ (KV) channel family are suggested to control the resting membrane potential and the repolarization phase of the action potential in urinary bladder smooth muscle (UBSM). Recent studies report that stromatoxin-1, a pept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db8b60ca0a80b16e9aa93720605097bb
https://doi.org/10.1152/ajpregu.00036.2010
https://doi.org/10.1152/ajpregu.00036.2010
Publikováno v:
Journal of Urology. 181:2355-2365
We investigated the functional role of K(+) channels for regulating spontaneous activity in mouse bladder detrusor smooth muscle.The effects of different K(+) channels blockers on spontaneous changes in membrane potential and intracellular Ca(2+) dyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b27f27093d98044de175ab9102ae6f8
https://doi.org/10.1016/j.juro.2009.01.013
https://doi.org/10.1016/j.juro.2009.01.013
Autor:
Louis H. Philipson, David A. Jacobson
Publikováno v:
Diabetes, Obesity and Metabolism. 9:89-98
Coordinated electrical activity allows pancreatic beta-cells to respond to secretagogues with calcium entry followed by insulin secretion. Metabolism of glucose affects multiple membrane proteins including ion channels, transporters and pumps that co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee5037ef9b0de393074aa40c17ef8aaf
https://doi.org/10.1111/j.1463-1326.2007.00784.x
https://doi.org/10.1111/j.1463-1326.2007.00784.x