The translocator protein (TSPO) is prodromal to mitophagy loss in neurotoxicity.

Autor: Frison M; Department of Comparative Biomedical Sciences, The Royal Veterinary College, University of London, Royal College Street, London, United Kingdom.; MRC Mitochondrial Biology Unit, Cambridge Biomedical Campus, Cambridge, United Kingdom., Faccenda D; Department of Comparative Biomedical Sciences, The Royal Veterinary College, University of London, Royal College Street, London, United Kingdom., Abeti R; Ataxia Centre, Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square London, United Kingdom., Rigon M; Department of Comparative Biomedical Sciences, The Royal Veterinary College, University of London, Royal College Street, London, United Kingdom.; Department of Biology, University of Rome TorVergata, Via della Ricerca Scientifica, Rome, Italy., Strobbe D; Department of Biology, University of Rome TorVergata, Via della Ricerca Scientifica, Rome, Italy., England-Rendon BS; Department of Comparative Biomedical Sciences, The Royal Veterinary College, University of London, Royal College Street, London, United Kingdom., Cash D; Department of Neuroimaging, Institute of Psychiatry, King's College London, Camberwell, United Kingdom., Barnes K; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, United Kingdom., Sadeghian M; Department of Neuroinflammation, UCL Queen Square Institute of Neurology, London, United Kingdom., Sajic M; Department of Neuroinflammation, UCL Queen Square Institute of Neurology, London, United Kingdom., Wells LA; Imanova Limited, Centre for Imaging Sciences, Imperial College London, Hammersmith Hospital, London, United Kingdom., Xia D; Department of Comparative Biomedical Sciences, The Royal Veterinary College, University of London, Royal College Street, London, United Kingdom., Giunti P; Ataxia Centre, Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square London, United Kingdom., Smith K; Department of Neuroinflammation, UCL Queen Square Institute of Neurology, London, United Kingdom., Mortiboys H; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, United Kingdom., Turkheimer FE; Department of Neuroimaging, Institute of Psychiatry, King's College London, Camberwell, United Kingdom., Campanella M; Department of Comparative Biomedical Sciences, The Royal Veterinary College, University of London, Royal College Street, London, United Kingdom. mcampanella@rvc.ac.uk.; Department of Biology, University of Rome TorVergata, Via della Ricerca Scientifica, Rome, Italy. mcampanella@rvc.ac.uk.; University College London Consortium for Mitochondrial Research, London, United Kingdom. mcampanella@rvc.ac.uk.

Publikováno v: Molecular psychiatry [Mol Psychiatry] 2021 Jul; Vol. 26 (7), pp. 2721-2739. Date of Electronic Publication: 2021 Mar 04.

Pyroptosis targeting via mitochondria: An educated guess to innovate COVID-19 therapies.

Autor: Singh A; Department of Comparative Biomedical Sciences, The Royal Veterinary College, University of London, London, UK., Strobbe D; Department of Biology, University of Rome 'Tor Vergata', Rome, Italy., Campanella M; Department of Comparative Biomedical Sciences, The Royal Veterinary College, University of London, London, UK.; Department of Biology, University of Rome 'Tor Vergata', Rome, Italy.; Department of Cell and Developmental Biology, Consortium for Mitochondrial Research (CfMR), University College London, London, UK.

Publikováno v: British journal of pharmacology [Br J Pharmacol] 2022 May; Vol. 179 (10), pp. 2081-2085. Date of Electronic Publication: 2021 Oct 10.

The role of mtDNA haplogroups on metabolic features in narcolepsy type 1.

Autor: Caporali L; IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna (IT)), Italy., Moresco M; IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna (IT)), Italy., Pizza F; IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna (IT)), Italy; Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna (IT)), Italy., La Morgia C; IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna (IT)), Italy; Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna (IT)), Italy., Fiorini C; IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna (IT)), Italy; Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna (IT)), Italy., Strobbe D; Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna (IT)), Italy., Zenesini C; IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna (IT)), Italy., Hooshiar Kashani B; Department of Biology and Biotechnology 'Lazzaro Spallanzani' (DBB), University of Pavia, Pavia (IT), Italy., Torroni A; Department of Biology and Biotechnology 'Lazzaro Spallanzani' (DBB), University of Pavia, Pavia (IT), Italy., Pagotto U; Unit of Endocrinology and Prevention and Care of Diabetes, Department of Medical and Surgical Sciences, St. Orsola Policlinic, University of Bologna, Bologna (IT), Italy., Carelli V; IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna (IT)), Italy; Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna (IT)), Italy., Plazzi G; IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna (IT)), Italy; Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy. Electronic address: giuseppe.plazzi@unibo.it.

Publikováno v: Mitochondrion [Mitochondrion] 2022 Mar; Vol. 63, pp. 37-42. Date of Electronic Publication: 2022 Jan 17.

DJ‐1 as a Novel Therapeutic Target for Mitigating Myocardial Ischemia–Reperfusion Injury.

Autor: Zhou, Jia-Bin¹ (AUTHOR), Wei, Tian-Peng¹ (AUTHOR), Wu, Dan¹ (AUTHOR), Zhou, Feng¹ (AUTHOR), Wang, Ru-Xing¹ (AUTHOR) ruxingw@njmu.edu.cn, Pandey, Vivek¹ (AUTHOR) vivek.pandey@uky.edu

Publikováno v: Cardiovascular Therapeutics. 12/12/2024, Vol. 2024, p1-7. 7p.

A Comprehensive Functional Investigation of the Human Translocator Protein 18 kDa (TSPO) in a Novel Human Neuronal Cell Knockout Model.

Autor: Bader, Stefanie¹ (AUTHOR) stefanie.bader@ukr.de, Jahner, Tatjana¹ (AUTHOR) vladimir.milenkovic@ukr.de, Dörfelt, Anett¹ (AUTHOR), Melchner, Doris¹ (AUTHOR), Cardon, Iseline¹ (AUTHOR), Siegmund, Heiko I.² (AUTHOR), Brochhausen, Christoph³ (AUTHOR), Rupprecht, Rainer¹ (AUTHOR), Milenkovic, Vladimir M.¹ (AUTHOR), Wetzel, Christian H.¹ (AUTHOR) christian.wetzel@ukr.de

Publikováno v: International Journal of Molecular Sciences. Dec2024, Vol. 25 Issue 23, p12882. 26p.