Tuning the surface coating of IONs toward efficient sonochemical tethering and sustained liberation of topoisomerase II poisons

Autor: Michalkova H, Strmiska V, Kudr J, Skubalova Z, Tesarova B, Svec P, Richtera L, Zitka O, Adam V, Heger Z

Publikováno v: International Journal of Nanomedicine, Vol Volume 14, Pp 7609-7624 (2019)

Hana Michalkova,1 Vladislav Strmiska,1 Jiri Kudr,1,2 Zuzana Skubalova,1 Barbora Tesarova,1 Pavel Svec,1 Lukas Richtera,1,2 Ondrej Zitka,1,2 Vojtech Adam,1,2 Zbynek Heger1,2 1Department of Chemistry and Biochemistry, Mendel University in Brno, Brno CZ

Externí odkaz: https://doaj.org/article/1dfa01a9b89948fd85807465b938ed5a

Investigating the interplay between sarcosine and Ca2+-dependent signaling in prostate cells

Autor: Strmiska, V., Buchtelova, H., Michalek, P., Krizkova, S., Vojtech Adam, Heger, Z.

Publikováno v: MendelNet 2018. 2019, p. 532-536.
ResearcherID

It has been shown that sarcosine supplementation stimulates proliferation and invassivenes of prostate cells. Nevertheless, the exact molecular mechanism responsible for this phenomenon is not known. In the present study we demonstrate that sarcosine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4ed2a24176911747e8f836617cca845d
https://hdl.handle.net/11012/178388

Evaluation of cytotoxicity of biphasic TiO2 nanoparticles with organic surface coatings

Autor: Skubalova, Z., Buchtelova, H., Strmiska, V., Dostalova, S., Michalek, P., Krizkova, S., Vojtech Adam, Heger, Z.

Publikováno v: MendelNet 2018. 2019, p. 522-526.
ResearcherID

Titanium dioxide nanoparticles (TiO2 NPs) are used in lots of human applications because of their extraordinary nano scaled properties. Particularly, due to their photoprotective properties, they are used in topical dermatologic preparation and also

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8572bae5894fd97ee9922b1b67017ecb
https://hdl.handle.net/11012/178386

CDC7-independent G1/S transition revealed by targeted protein degradation.

Autor: Suski JM; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Ratnayeke N; Department of Cell and Developmental Biology, Weill Cornell Medicine, New York, NY, USA.; Department of Chemical and Systems Biology, Stanford University, Stanford, CA, USA., Braun M; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.; Department of Pathology, Chair of Oncology, Medical University of Lodz, Lodz, Poland., Zhang T; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Strmiska V; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Michowski W; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Can G; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA., Simoneau A; Massachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, MA, USA.; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Snioch K; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Cup M; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Sullivan CM; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Wu X; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Nowacka J; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Branigan TB; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Pack LR; Department of Cell and Developmental Biology, Weill Cornell Medicine, New York, NY, USA.; Department of Chemical and Systems Biology, Stanford University, Stanford, CA, USA., DeCaprio JA; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Geng Y; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Zou L; Massachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, MA, USA.; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Gygi SP; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Walter JC; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA., Meyer T; Department of Cell and Developmental Biology, Weill Cornell Medicine, New York, NY, USA. tom4003@med.cornell.edu., Sicinski P; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA. peter_sicinski@dfci.harvard.edu.; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA. peter_sicinski@dfci.harvard.edu.

Publikováno v: Nature [Nature] 2022 May; Vol. 605 (7909), pp. 357-365. Date of Electronic Publication: 2022 May 04.

Targeting cell-cycle machinery in cancer.

Autor: Suski JM; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA., Braun M; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA; Department of Pathology, Chair of Oncology, Medical University of Lodz, 92-213 Lodz, Poland., Strmiska V; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA., Sicinski P; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA. Electronic address: peter_sicinski@dfci.harvard.edu.

Publikováno v: Cancer cell [Cancer Cell] 2021 Jun 14; Vol. 39 (6), pp. 759-778. Date of Electronic Publication: 2021 Apr 22.