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αβ-T Cells Engineered to Express γδ-T Cell Receptors Can Kill Neuroblastoma Organoids Independent of MHC-I Expression

Autor: Strijker, Josephine G M, Pscheid, Ronja, Drent, Esther, van der Hoek, Jessica J F, Koopmans, Bianca, Ober, Kimberley, van Hooff, Sander R, Kholosy, Waleed M, Cornel, Annelisa M, Coomans, Chris, Bisso, Andrea, van Loenen, Marleen M, Molenaar, Jan J, Wienke, Judith, Afd Pharmaceutics, Pharmaceutics

Publikováno v: Journal of Personalized Medicine, 11(9):923. MDPI Multidisciplinary Digital Publishing Institute
Journal of Personalized Medicine
Volume 11
Issue 9
Journal of Personalized Medicine, 11(9), 1. Multidisciplinary Digital Publishing Institute (MDPI)
Journal of Personalized Medicine, Vol 11, Iss 923, p 923 (2021)

Currently ~50% of patients with a diagnosis of high-risk neuroblastoma will not survive due to relapsing or refractory disease. Recent innovations in immunotherapy for solid tumors are highly promising, but the low MHC-I expression of neuroblastoma r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5758e9e2b160808f1a7ecbbc74004a7
https://pure.amc.nl/en/publications/t-cells-engineered-to-express-t-cell-receptors-can-kill-neuroblastoma-organoids-independent-of-mhci-expression(2a6b190d-9b38-4b31-86ec-ddf3fa05033d).html

αβ-T Cells Engineered to Express γδ-T Cell Receptors Can Kill Neuroblastoma Organoids Independent of MHC-I Expression.

Autor: Strijker JGM; Princess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands., Pscheid R; Gadeta B.V., 3584 CM Utrecht, The Netherlands., Drent E; Gadeta B.V., 3584 CM Utrecht, The Netherlands., van der Hoek JJF; Princess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands., Koopmans B; Princess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands., Ober K; Princess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands., van Hooff SR; Princess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands., Kholosy WM; Princess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands., Cornel AM; Princess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands.; University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands., Coomans C; Gadeta B.V., 3584 CM Utrecht, The Netherlands., Bisso A; Gadeta B.V., 3584 CM Utrecht, The Netherlands., van Loenen MM; Gadeta B.V., 3584 CM Utrecht, The Netherlands., Molenaar JJ; Princess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands., Wienke J; Princess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The Netherlands.

Publikováno v: Journal of personalized medicine [J Pers Med] 2021 Sep 17; Vol. 11 (9). Date of Electronic Publication: 2021 Sep 17.