Zobrazeno 1 - 10 of 211 pro vyhledávání: '"Strecker, TE"'
1
Akademický článek
Dual inhibition of HERs and PD-1 counteract resistance in KRASG12C-mutant head and neck cancer.
Autor: Novoplansky, Ofra1,2 (AUTHOR), Jagadeeshan, Sankar1,2 (AUTHOR), Prasad, Manu1,2 (AUTHOR), Yegodayev, Ksenia M.1,2 (AUTHOR), Marripati, Divyasree1,2 (AUTHOR), Shareb, Raghda Abu1,2 (AUTHOR), Greenshpan, Yariv1,2 (AUTHOR), Mathukkada, Sooraj1,2 (AUTHOR), Ben-Lulu, Talal1,2 (AUTHOR), Bhattacharya, Baisali1,2 (AUTHOR), Porgador, Angel1,2 (AUTHOR), Kong, Dexin3 (AUTHOR), Brägelmann, Johannes4,5,6 (AUTHOR), Gutkind, J. Silvio7 (AUTHOR), Elkabets, Moshe1,2 (AUTHOR) moshee@bgu.ac.il
Publikováno v: Journal of Experimental & Clinical Cancer Research (17569966). 11/20/2024, Vol. 43, p1-23. 23p.
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2
Akademický článek
Bioreductively Activatable Prodrug Conjugates of Combretastatin A-1 and Combretastatin A-4 as Anticancer Agents Targeted toward Tumor-Associated Hypoxia.
Autor: Winn BA; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States., Devkota L; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States., Kuch B; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States., MacDonough MT; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States., Strecker TE; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States., Wang Y; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States., Shi Z; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States., Gerberich JL; Predictive Imaging Research Laboratory, Department of Radiology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9058, United States., Mondal D; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States., Ramirez AJ; Mass Spectrometry Center, Baylor University, One Bear Place #97046, Waco, Texas 76798-7046, United States., Hamel E; Screening Technologies Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Frederick National Laboratory for Cancer Research, National Institutes of Health, Frederick, Maryland 21702, United States., Chaplin DJ; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States.; Fast Biopharma Ltd., 10 Aston Park, Aston Rowant, OX49 5SW, United Kingdom., Davis P; Fast Biopharma Ltd., 10 Aston Park, Aston Rowant, OX49 5SW, United Kingdom., Mason RP; Predictive Imaging Research Laboratory, Department of Radiology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9058, United States., Trawick ML; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States., Pinney KG; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States.
Publikováno v: Journal of natural products [J Nat Prod] 2020 Apr 24; Vol. 83 (4), pp. 937-954. Date of Electronic Publication: 2020 Mar 20.
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3
Akademický článek
Structure Guided Design, Synthesis, and Biological Evaluation of Novel Benzosuberene Analogues as Inhibitors of Tubulin Polymerization.
Autor: Niu H; Department of Chemistry and Biochemistry , Baylor University , One Bear Place, No. 97348 , Waco , Texas 76798-7348 , United States., Strecker TE; Department of Chemistry and Biochemistry , Baylor University , One Bear Place, No. 97348 , Waco , Texas 76798-7348 , United States., Gerberich JL; Department of Radiology , The University of Texas Southwestern Medical Center , 5323 Harry Hines Boulevard , Dallas , Texas 75390-9058 , United States., Campbell JW 3rd; Department of Radiology , The University of Texas Southwestern Medical Center , 5323 Harry Hines Boulevard , Dallas , Texas 75390-9058 , United States., Saha D; Department of Radiology Oncology, Division of Molecular Radiation Biology , The University of Texas Southwestern Medical Center , 2201 Inwood Road , Dallas , Texas 75390-9187 , United States., Mondal D; Department of Chemistry and Biochemistry , Baylor University , One Bear Place, No. 97348 , Waco , Texas 76798-7348 , United States., Hamel E; Screening Technologies Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis , National Cancer Institute, Frederick National Laboratory for Cancer Research, National Institutes of Health , Frederick , Maryland 21702 , United States., Chaplin DJ; Department of Chemistry and Biochemistry , Baylor University , One Bear Place, No. 97348 , Waco , Texas 76798-7348 , United States.; Mateon Therapeutics, Inc. , 701 Gateway Boulevard, Suite 210 , South San Francisco , California 94080 , United States., Mason RP; Department of Radiology , The University of Texas Southwestern Medical Center , 5323 Harry Hines Boulevard , Dallas , Texas 75390-9058 , United States., Trawick ML; Department of Chemistry and Biochemistry , Baylor University , One Bear Place, No. 97348 , Waco , Texas 76798-7348 , United States., Pinney KG; Department of Chemistry and Biochemistry , Baylor University , One Bear Place, No. 97348 , Waco , Texas 76798-7348 , United States.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2019 Jun 13; Vol. 62 (11), pp. 5594-5615. Date of Electronic Publication: 2019 May 24.
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4
Akademický článek
Synthesis and biological evaluation of structurally diverse α-conformationally restricted chalcones and related analogues.
Autor: Maguire CJ; Department of Chemistry and Biochemistry , Baylor University , One Bear Place #97348 , Waco , TX 76798-7348 , USA . Email: Kevin_Pinney@baylor.edu ; Tel: +1 (254) 710 4117., Carlson GJ; Department of Chemistry and Biochemistry , Baylor University , One Bear Place #97348 , Waco , TX 76798-7348 , USA . Email: Kevin_Pinney@baylor.edu ; Tel: +1 (254) 710 4117., Ford JW; Department of Chemistry and Biochemistry , Baylor University , One Bear Place #97348 , Waco , TX 76798-7348 , USA . Email: Kevin_Pinney@baylor.edu ; Tel: +1 (254) 710 4117., Strecker TE; Department of Chemistry and Biochemistry , Baylor University , One Bear Place #97348 , Waco , TX 76798-7348 , USA . Email: Kevin_Pinney@baylor.edu ; Tel: +1 (254) 710 4117., Hamel E; Screening Technologies Branch , Developmental Therapeutics Program , Division of Cancer Treatment and Diagnosis , National Cancer Institute , Frederick National Laboratory for Cancer Research , National Institutes of Health , Frederick , MD 21702 , USA., Trawick ML; Department of Chemistry and Biochemistry , Baylor University , One Bear Place #97348 , Waco , TX 76798-7348 , USA . Email: Kevin_Pinney@baylor.edu ; Tel: +1 (254) 710 4117., Pinney KG; Department of Chemistry and Biochemistry , Baylor University , One Bear Place #97348 , Waco , TX 76798-7348 , USA . Email: Kevin_Pinney@baylor.edu ; Tel: +1 (254) 710 4117.
Publikováno v: MedChemComm [Medchemcomm] 2019 Jun 04; Vol. 10 (8), pp. 1445-1456. Date of Electronic Publication: 2019 Jun 04 (Print Publication: 2019).
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5
Akademický článek
Synthesis of dihydronaphthalene analogues inspired by combretastatin A-4 and their biological evaluation as anticancer agents.
Autor: Maguire CJ; Department of Chemistry and Biochemistry , Baylor University , One Bear Place #97348 , Waco , TX 76798-7348 , USA . Email: Kevin_Pinney@baylor.edu ; Tel: +(254) 710 4117., Chen Z; Department of Chemistry and Biochemistry , Baylor University , One Bear Place #97348 , Waco , TX 76798-7348 , USA . Email: Kevin_Pinney@baylor.edu ; Tel: +(254) 710 4117., Mocharla VP; Department of Chemistry and Biochemistry , Baylor University , One Bear Place #97348 , Waco , TX 76798-7348 , USA . Email: Kevin_Pinney@baylor.edu ; Tel: +(254) 710 4117., Sriram M; Department of Chemistry and Biochemistry , Baylor University , One Bear Place #97348 , Waco , TX 76798-7348 , USA . Email: Kevin_Pinney@baylor.edu ; Tel: +(254) 710 4117., Strecker TE; Department of Chemistry and Biochemistry , Baylor University , One Bear Place #97348 , Waco , TX 76798-7348 , USA . Email: Kevin_Pinney@baylor.edu ; Tel: +(254) 710 4117., Hamel E; Screening Technologies Branch , Developmental Therapeutics Program , Division of Cancer Treatment and Diagnosis , National Cancer Institute , Frederick National Laboratory for Cancer Research , National Institutes of Health , Frederick , MD 21702 , USA., Zhou H; Department of Radiology , The University of Texas Southwestern Medical Center , 5323 Harry Hines Boulevard , Dallas , TX 75390-9058 , USA., Lopez R; Department of Radiology , The University of Texas Southwestern Medical Center , 5323 Harry Hines Boulevard , Dallas , TX 75390-9058 , USA., Wang Y; Department of Chemistry and Biochemistry , Baylor University , One Bear Place #97348 , Waco , TX 76798-7348 , USA . Email: Kevin_Pinney@baylor.edu ; Tel: +(254) 710 4117., Mason RP; Department of Radiology , The University of Texas Southwestern Medical Center , 5323 Harry Hines Boulevard , Dallas , TX 75390-9058 , USA., Chaplin DJ; Department of Chemistry and Biochemistry , Baylor University , One Bear Place #97348 , Waco , TX 76798-7348 , USA . Email: Kevin_Pinney@baylor.edu ; Tel: +(254) 710 4117.; Mateon Therapeutics, Inc. , 701 Gateway Boulevard, Suite 210 , South San Francisco , CA 94080 , USA., Trawick ML; Department of Chemistry and Biochemistry , Baylor University , One Bear Place #97348 , Waco , TX 76798-7348 , USA . Email: Kevin_Pinney@baylor.edu ; Tel: +(254) 710 4117., Pinney KG; Department of Chemistry and Biochemistry , Baylor University , One Bear Place #97348 , Waco , TX 76798-7348 , USA . Email: Kevin_Pinney@baylor.edu ; Tel: +(254) 710 4117.
Publikováno v: MedChemComm [Medchemcomm] 2018 Aug 24; Vol. 9 (10), pp. 1649-1662. Date of Electronic Publication: 2018 Aug 24 (Print Publication: 2018).
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6
Akademický článek
Synthesis and biological evaluation of a water-soluble phosphate prodrug salt and structural analogues of KGP94, a lead inhibitor of cathepsin L.
Autor: Parker EN; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, TX 76798-7348, United States., Odutola SO; Institute of Biomedical Studies, Baylor University, One Bear Place #97224, Waco, TX 76798-7224, United States., Wang Y; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, TX 76798-7348, United States., Strecker TE; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, TX 76798-7348, United States., Mukherjee R; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, TX 76798-7348, United States., Shi Z; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, TX 76798-7348, United States., Chaplin DJ; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, TX 76798-7348, United States; Mateon Therapeutics, Inc., 701 Gateway Blvd, Suite 210, South San Francisco, CA 94080, United States., Trawick ML; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, TX 76798-7348, United States; Institute of Biomedical Studies, Baylor University, One Bear Place #97224, Waco, TX 76798-7224, United States; Mateon Therapeutics, Inc., 701 Gateway Blvd, Suite 210, South San Francisco, CA 94080, United States. Electronic address: Mary_Lynn_Trawick@baylor.edu., Pinney KG; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, TX 76798-7348, United States; Institute of Biomedical Studies, Baylor University, One Bear Place #97224, Waco, TX 76798-7224, United States; Mateon Therapeutics, Inc., 701 Gateway Blvd, Suite 210, South San Francisco, CA 94080, United States. Electronic address: Kevin_Pinney@baylor.edu.
Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2017 Mar 01; Vol. 27 (5), pp. 1304-1310. Date of Electronic Publication: 2016 Dec 21.
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7
Akademický článek
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8
Akademický článek
Synthesis and Biological Evaluation of Benzocyclooctene-based and Indene-based Anticancer Agents that Function as Inhibitors of Tubulin Polymerization.
Autor: Herdman CA; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States., Strecker TE; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States., Tanpure RP; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States., Chen Z; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States., Winters A; Prognostic Imaging Research Laboratory, Department of Radiology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9058, United States., Gerberich J; Prognostic Imaging Research Laboratory, Department of Radiology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9058, United States., Liu L; Prognostic Imaging Research Laboratory, Department of Radiology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9058, United States., Hamel E; Screening Technologies Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Frederick National Laboratory for Cancer Research, National Institutes of Health, Frederick, MD 21702, United States., Mason RP; Prognostic Imaging Research Laboratory, Department of Radiology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9058, United States., Chaplin DJ; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States; Mateon Therapeutics, Inc., 701 Gateway Boulevard, Suite 210, South San Francisco, California 94080, United States., Trawick ML; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States., Pinney KG; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States.
Publikováno v: MedChemComm [Medchemcomm] 2016 Dec 01; Vol. 7 (12), pp. 2418-2427. Date of Electronic Publication: 2016 Sep 22.
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9
Akademický článek
Design, synthesis, and biological evaluation of water-soluble amino acid prodrug conjugates derived from combretastatin, dihydronaphthalene, and benzosuberene-based parent vascular disrupting agents.
Autor: Devkota L; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States., Lin CM; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States., Strecker TE; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States., Wang Y; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States., Tidmore JK; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States., Chen Z; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States., Guddneppanavar R; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States., Jelinek CJ; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States., Lopez R; Department of Radiology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9058, United States., Liu L; Department of Radiology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9058, United States., Hamel E; Screening Technologies Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Frederick National Laboratory for Cancer Research, National Institutes of Health, Frederick, MD 21702, United States., Mason RP; Department of Radiology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9058, United States., Chaplin DJ; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States.; OXiGENE Inc., 701 Gateway Boulevard, Suite 210, South San Francisco, California 94080, United States., Trawick ML; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States., Pinney KG; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States.
Publikováno v: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2016 Mar 01; Vol. 24 (5), pp. 938-956. Date of Electronic Publication: 2016 Jan 06.
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10
Akademický článek
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