Generation of floxed Spag6l mice and disruption of the gene by crossing to a Hprt-Cre line.

Autor: Man Y; Department of Occupational and Environmental Health, School of Public Health, Wuhan University of Science and Technology, Wuhan, Hubei, China., Li W; Department of Physiology, Wayne State University, Detroit, Michigan, USA., Yap YT; Department of Physiology, Wayne State University, Detroit, Michigan, USA., Kearney A; Department of Physiology, Wayne State University, Detroit, Michigan, USA., Yee SP; Health Center, University of Connecticut, Storrs, Connecticut, USA., Strauss JF 3rd; Center for Research on Reproduction and Women's Health, Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Harding P; Hypertension and Vascular Research Division, Henry Ford Health System, Detroit, Michigan, USA., Song S; Department of Occupational and Environmental Health, School of Public Health, Wuhan University of Science and Technology, Wuhan, Hubei, China., Zhang L; Department of Occupational and Environmental Health, School of Public Health, Wuhan University of Science and Technology, Wuhan, Hubei, China., Zhang Z; Department of Physiology, Wayne State University, Detroit, Michigan, USA.; Department of Obstetrics and Gynecology, Wayne State University, Detroit, Michigan, USA.

Publikováno v: Genesis (New York, N.Y. : 2000) [Genesis] 2023 Jul; Vol. 61 (3-4), pp. e23512. Date of Electronic Publication: 2023 Apr 14.

Single-Cell RNA-Seq Identifies Pathways and Genes Contributing to the Hyperandrogenemia Associated with Polycystic Ovary Syndrome.

Autor: Harris RA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., McAllister JM; Department of Pathology, Penn State Hershey College of Medicine, Hershey, PA 17033, USA., Strauss JF 3rd; Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Jun 25; Vol. 24 (13). Date of Electronic Publication: 2023 Jun 25.

Does the Vaginal Microbiome Operate Differently by Race to Influence Risk of Precervical Cancer?

Autor: Tossas KY; Department of Health Behavior and Policy and Division of Epidemiology, School of Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.; Department of Family Medicine and Population Health, Division of Epidemiology, School of Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.; Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA.; Center for Microbiome Engineering and Data Analysis, Virginia Commonwealth University, Richmond, Virginia, USA., Zhu B; Center for Microbiome Engineering and Data Analysis, Virginia Commonwealth University, Richmond, Virginia, USA.; Department of Microbiology and Immunology, Virginia Commonwealth University, Richmond, Virginia, USA., Perera RA; Department of Biostatistics, School of Medicine, Virginia Commonwealth University, Richmond, Virginia, USA., Serrano MG; Center for Microbiome Engineering and Data Analysis, Virginia Commonwealth University, Richmond, Virginia, USA.; Department of Microbiology and Immunology, Virginia Commonwealth University, Richmond, Virginia, USA., Sullivan S; Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA.; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Virginia Commonwealth University, Richmond, Virginia, USA., Sayeed S; Department of Pathology, Virginia Commonwealth University, Richmond, Virginia, USA., Strauss JF 3rd; Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Winn RA; Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA., Buck GA; Center for Microbiome Engineering and Data Analysis, Virginia Commonwealth University, Richmond, Virginia, USA.; Department of Microbiology and Immunology, Virginia Commonwealth University, Richmond, Virginia, USA., Seewaldt VL; Department of Population Sciences, City of Hope, Duarte, California, USA.

Publikováno v: Journal of women's health (2002) [J Womens Health (Larchmt)] 2023 May; Vol. 32 (5), pp. 553-560. Date of Electronic Publication: 2023 Mar 10.

Reduced SPAG17 Expression in Systemic Sclerosis Triggers Myofibroblast Transition and Drives Fibrosis.

Autor: Sapao P; Department of Chemistry, College of Humanities and Sciences, Virginia Commonwealth University, Richmond, Virginia, USA., Roberson EDO; Division of Rheumatology, John T. Milliken Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA; Department of Genetics, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA., Shi B; Scleroderma Program, Feinberg School of Medicine, Northwestern University, Chicago, Ilinois, USA., Assassi S; Division of Rheumatology, Department of Internal Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA., Skaug B; Division of Rheumatology, Department of Internal Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA., Lee F; Department of Physiology & Biophysics, College of Medicine, University of Illinois at Chicago, Chicago, Ilinois, USA., Naba A; Department of Physiology & Biophysics, College of Medicine, University of Illinois at Chicago, Chicago, Ilinois, USA., Perez White BE; Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, Ilinois, USA., Córdova-Fletes C; Departamento de Bioquímica y Medicina Molecular, Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, México., Tsou PS; Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., Sawalha AH; Department of Pediatrics, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA; The UPMC Lupus Center of Excellence, Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Gudjonsson JE; Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, Michigan, USA; Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA., Ma F; Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, Michigan, USA; Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA., Verma P; Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., Bhattacharyya D; Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., Carns M; Scleroderma Program, Feinberg School of Medicine, Northwestern University, Chicago, Ilinois, USA., Strauss JF 3rd; Department of Obstetrics & Gynecology, Virginia Commonwealth University, Richmond, Virginia, USA., Sicard D; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minesota, USA., Tschumperlin DJ; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minesota, USA., Champer MI; Department of Biomedical Engineering, College of Engineering, University of Wisconsin-Madison, Madison, Wincosin, USA., Campagnola PJ; Department of Biomedical Engineering, College of Engineering, University of Wisconsin-Madison, Madison, Wincosin, USA., Teves ME; Department of Obstetrics & Gynecology, Virginia Commonwealth University, Richmond, Virginia, USA. Electronic address: maria.teves@vcuhealth.org., Varga J; Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.

Publikováno v: The Journal of investigative dermatology [J Invest Dermatol] 2023 Feb; Vol. 143 (2), pp. 284-293. Date of Electronic Publication: 2022 Sep 15.

Reconstitution of human adrenocortical specification and steroidogenesis using induced pluripotent stem cells.

Autor: Sakata Y; Department of Biomedical Sciences, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA 19104, USA; Institute for Regenerative Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Cheng K; Department of Biomedical Sciences, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA 19104, USA; Institute for Regenerative Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Mayama M; Department of Biomedical Sciences, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA 19104, USA; Institute for Regenerative Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Seita Y; Department of Biomedical Sciences, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA 19104, USA; Institute for Regenerative Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Bell Research Center for Reproductive Health and Cancer, Nagoya 460-0003, Japan., Detlefsen AJ; Department of Biochemistry and Biophysics, Perelman School of Medicine University of Pennsylvania, Philadelphia, PA 19104, USA., Mesaros CA; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Center of Excellence in Environmental Toxicology, University of Pennsylvania, Philadelphia, PA 19104, USA., Penning TM; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Center of Excellence in Environmental Toxicology, University of Pennsylvania, Philadelphia, PA 19104, USA., Shishikura K; Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104, USA., Yang W; Institute for Regenerative Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Auchus RJ; Division of Metabolism, Endocrinology, and Diabetes, Departments of Internal Medicine and Pharmacology, University of Michigan, Ann Arbor, MI 48105, USA., Strauss JF 3rd; Department of Obstetrics and Gynecology, University of Pennsylvania, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Sasaki K; Department of Biomedical Sciences, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA 19104, USA; Institute for Regenerative Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Center of Excellence in Environmental Toxicology, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA 19104, USA. Electronic address: ksasaki@upenn.edu.

Publikováno v: Developmental cell [Dev Cell] 2022 Nov 21; Vol. 57 (22), pp. 2566-2583.e8.