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PIK3CA and p53 Mutations Promote 4NQO-Initated Head and Neck Tumor Progression and Metastasis in Mice.

Autor: García-Carracedo D; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, New York.; Department of Otolaryngology - Head and Neck Surgery, Columbia University Irving Medical Center, New York, New York., Cai Y; Department of Otolaryngology - Head and Neck Surgery, Columbia University Irving Medical Center, New York, New York., Qiu W; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, New York.; Department of Pathology & Cell Biology, Columbia University Irving Medical Center, New York, New York., Saeki K; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, New York.; Department of Pathology & Cell Biology, Columbia University Irving Medical Center, New York, New York., Friedman RA; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, New York.; Department of Biomedical Informatics, Columbia University Medical Center, New York, New York., Lee A; Department of Otolaryngology - Head and Neck Surgery, Columbia University Irving Medical Center, New York, New York., Li Y; Department of Genetics and Development, Columbia University Medical Center, New York, New York., Goldberg EM; Department of Genetics and Development, Columbia University Medical Center, New York, New York., Stratikopoulos EE; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York., Parsons R; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York., Lu C; Department of Genetics and Development, Columbia University Medical Center, New York, New York., Efstratiadis A; Biomedical Research Foundation, Academy of Athens, Athens, Greece., Philipone EM; Division of Oral and Maxillofacial Pathology, Columbia University College of Dental Medicine, New York, New York., Yoon AJ; Division of Oral and Maxillofacial Pathology, Columbia University College of Dental Medicine, New York, New York., Su GH; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, New York. gs2157@columbia.edu.; Department of Otolaryngology - Head and Neck Surgery, Columbia University Irving Medical Center, New York, New York.; Department of Pathology & Cell Biology, Columbia University Irving Medical Center, New York, New York.

Publikováno v: Molecular cancer research : MCR [Mol Cancer Res] 2020 Jun; Vol. 18 (6), pp. 822-834. Date of Electronic Publication: 2020 Mar 09.

Mouse ER+/PIK3CA ^H1047R breast cancers caused by exogenous estrogen are heterogeneously dependent on estrogen and undergo BIM-dependent apoptosis with BH3 and PI3K agents.

Autor: Stratikopoulos EE; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Kiess N; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Szabolcs M; Department of Pathology, Columbia University Medical Center, New York, NY, 10032, USA., Pegno S; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Kakit C; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Wu X; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Poulikakos PI; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Cheung P; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Schmidt H; Department of Surgery, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Parsons R; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. ramon.parsons@mssm.edu.

Publikováno v: Oncogene [Oncogene] 2019 Jan; Vol. 38 (1), pp. 47-59. Date of Electronic Publication: 2018 Aug 03.

Kinase and BET Inhibitors Together Clamp Inhibition of PI3K Signaling and Overcome Resistance to Therapy.

Autor: Stratikopoulos EE; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, New York, NY 10029, USA., Dendy M; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, New York, NY 10029, USA., Szabolcs M; Department of Pathology, Columbia University Medical Center, New York, NY 10032, USA., Khaykin AJ; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, New York, NY 10029, USA., Lefebvre C; Inserm U981, Institut Gustave Roussy, 94805 Villejuif, France., Zhou MM; Department of Structural and Chemical Biology, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, New York, NY 10029, USA., Parsons R; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, New York, NY 10029, USA. Electronic address: ramon.parsons@mssm.edu.

Publikováno v: Cancer cell [Cancer Cell] 2015 Jun 08; Vol. 27 (6), pp. 837-51.

Isolation and characterization of microsatellite markers from the olive fly, Bactrocera oleae, and their cross-species amplification in the Tephritidae family.

Autor: Augustinos AA; Department of Biochemistry and Biotechnology, University of Thessaly, Thessaly, Greece. augustin@upatras.gr, Stratikopoulos EE, Drosopoulou E, Kakani EG, Mavragani-Tsipidou P, Zacharopoulou A, Mathiopoulos KD

Publikováno v: BMC genomics [BMC Genomics] 2008 Dec 19; Vol. 9, pp. 618. Date of Electronic Publication: 2008 Dec 19.