The state of GPCR research in 2004

Autor: Bartfai, T., Benovic, J.L., Bockaert, J., Bond, R.A., Bouvier, M., Christopoulos, A., Civelli, O., Devi, L.A., George, S.R., Inui, A., Kobilka, B., Leurs, R., Neubig, R., Pin, J.P., Quirion, R., Roques, B.P., Sakmar, T.P., Seifert, R., Stenkamp, R.E., Strange, P.G.

Publikováno v: Bartfai, T, Benovic, J L, Bockaert, J, Bond, R A, Bouvier, M, Christopoulos, A, Civelli, O, Devi, L A, George, S R, Inui, A, Kobilka, B, Leurs, R, Neubig, R, Pin, J P, Quirion, R, Roques, B P, Sakmar, T P, Seifert, R, Stenkamp, R E & Strange, P G 2004, ' The state of GPCR research in 2004 ', Nature Reviews Drug Discovery, vol. 3, no. 7, pp. 574-626 . https://doi.org/10.1038/nrd1458
Nature Reviews Drug Discovery, 3(7), 574-626. Nature Publishing Group

List of questions G-protein-coupled receptors (GPCRs) comprise the largest single class of cell-surface receptors, and have a history of being excellent therapeutic targets for a number of diseases. Yet several fundamental questions remain regarding

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https://research.vu.nl/en/publications/5f3edb59-aa3b-4e43-8d42-bbe65a0b6317

Mechanisms of ligand binding and efficacy at the human D[sub 2(short)] dopamine receptor.

Autor: Payne, S.L., Johansson, A.M., Strange, P.G.

Publikováno v: Journal of Neurochemistry; 9/1/2002, Vol. 82 Issue 5, p1106-1117, 12p

Alterations in β-adrenoceptor number and catecholamine content of chick atria after reversible sympathetic denervation with 6-hydroxydopamine.

Autor: Williams, K., Strange, P.G., Bennett, T.

Publikováno v: Naunyn-Schmiedeberg's Archives of Pharmacology; 1987, Vol. 336 Issue 1, p64-69, 6p

Comparison of the ability of dopamine receptor agonists to inhibit forskolin-stimulated adenosine 3'5'-cyclic monophosphate (cAMP) accumulation via D2L (long isoform) and D3 receptors expressed in Chinese hamster ovary (CHO) cells - Expression of the cloned D2A and D2B subtypes in a heterologous cell line

Autor: Hall, D.A., Strange, P.G.

Publikováno v: Biochemical Pharmacology; 1999, Vol. 58 Issue: 2 p285-289, 5p

Reconstitution of solubilised brain D 2dopamine receptors into phospholipid vesicles

Autor: Wheatley, M., Strange, P.G.

Publikováno v: FEBS Letters; January 1984, Vol. 166 Issue: 2 p389-392, 4p