Zobrazeno 1 - 10
of 2 638
pro vyhledávání: '"Strand transfer"'
Autor:
Yihui He, Yang Zhang, Jiaxin Zhen, Guangqiang Sun, Zhen Li, Bo Yang, Bin Yang, Keyi Chang, Xue Chen, Yulin Zhang, Caiping Guo, Wen Wang, Ping Wu, Tong Zhang, Lei Wang
Publikováno v:
Biosafety and Health, Vol 6, Iss 4, Pp 216-224 (2024)
Integrase strand transfer inhibitors (INSTIs) have emerged as the first-line choice for treating human immunodeficiency virus (HIV) infection due to their superior efficacy and safety. However, the impact of INSTIs on the development of neuropsychiat
Externí odkaz:
https://doaj.org/article/b2e65e9133524a798c8a3d2e1ec3ff10
Autor:
Julien De Greef, Mathilde Akue, Nadtha Panin, Kévin-Alexandre Delongie, Marina André, Gwenaëlle Mahieu, Emilia Hoste, Laure Elens, Leïla Belkhir, Vincent Haufroid
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Bictegravir, a key second-generation integrase strand transfer inhibitor in the treatment of HIV, is subject to active efflux transport mediated by ABCB1 (P-glycoprotein). Several coding variants of ABCB1 have been described and associated w
Externí odkaz:
https://doaj.org/article/673a1d72024c4c09bb675d1b896f6a08
Autor:
Lin Gan, Xiaoxin Xie, Yanhua Fu, Xiaoyan Yang, Shujing Ma, Linghong Kong, Chunli Song, Yebing Song, Tingting Ren, Hai Long
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background The effectiveness of post-exposure prophylaxis (PEP) depends on participants adherence, making it crucial to assess and compare regimen options to enhance human immunodeficiency virus (HIV) prophylaxis strategies. However, no pros
Externí odkaz:
https://doaj.org/article/3ef93f8e9f4e4da686d761b205951ce4
Autor:
Yusuke Kunimoto, Shinichi Hikasa, Masashi Ishihara, Mariko Tsukiji, Kazuko Nobori, Takeshi Kimura, Kenta Onishi, Yuuki Yamamoto, Kyohei Haruta, Yohei Kasiwabara, Kenji Fujii, Masahide Fukudo
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract Background People living with human immunodeficiency virus (PLWH) require high rates of medication adherence to antiretroviral therapy (ART) for a successful treatment outcome. Understanding the factors associated with incomplete adherence a
Externí odkaz:
https://doaj.org/article/3304f5aa4bbf4834a0d77016e6f74d23
Autor:
Dorcas Maruapula, Doreen Ditshwanelo, Marea N. Pema, Ontlametse T. Bareng, Wonderful T. Choga, Natasha O. Moraka, Patrick T. Mokgethi, Kaelo K. Seatla, Catherine K. Koofhethile, Boitumelo J. Zuze, Tendani Gaolathe, Molly Pretorius-Holme, Kebaneilwe Lebani, Joseph Makhema, Vlad Novitsky, Roger Shapiro, Shahin Lockman, Sikhulile Moyo, Simani Gaseitsiwe
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
BackgroundWe evaluated the prevalence of archived proviral drug resistance mutations (DRMs) associated with resistance to integrase strand transfer inhibitors (INSTIs) shortly before Botswana transitioned in 2016 to using dolutegravir (DTG)-based ant
Externí odkaz:
https://doaj.org/article/38caff23dfd94972b28750adba2eaf3b
Publikováno v:
Infectious Diseases and Therapy, Vol 13, Iss 6, Pp 1161-1175 (2024)
Abstract The human immunodeficiency virus type 2 (HIV-2) is a particular subtype of HIV, which is endemic in West Africa and is characterized by a more indolent course than HIV-1. As people living with HIV-2 (PWH-2) are at risk for the development of
Externí odkaz:
https://doaj.org/article/a75252dd6111481c8744c15378e1f488
Autor:
Jen-Yu Hsu, Hsin-Yun Sun, Ling-Ya Chen, Sui-Yuan Chang, Yu-Chung Chuang, Yu-Shan Huang, Yi-Ching Su, Wen-Chun Liu, Chien-Ching Hung
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 36, Iss , Pp 426-435 (2024)
ABSTRACT: Objectives: We aimed to investigate the evolution of weight, lipid profiles, and glucose homeostasis among virally suppressed people with HIV (PWH) who switched to bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF). Methods: PWH
Externí odkaz:
https://doaj.org/article/264676e3008d4fdf91ba4302578e0417
Autor:
Nivriti Hurbans, Panjasaram Naidoo
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Dolutegravir is an integrase strand transfer inhibitor that has been recommended for use in first-line antiretroviral regimens by the World Health Organisation and is currently being rolled out globally. There has been safety conc
Externí odkaz:
https://doaj.org/article/021ca8fd7ea14ca290dd7cda7b8016d2
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