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Parkinson's disease-associated mutations in DJ-1 modulate its dimerization in living cells

Autor: Repici, Mariaelena, Straatman, Kornelis R, Balduccio, Nadia, Enguita, Francisco J, Outeiro, Tiago F, Giorgini, Flaviano

Mutations in the protein DJ-1 cause recessive forms of early onset familial Parkinson's disease (PD). To date, most of the causative mutations studied destabilize formation of DJ-1 homodimers, which appears to be closely linked to its normal function

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::fbb34fe2300c3cd5429a03b066ef0260
https://publications.aston.ac.uk/id/eprint/38990/1/Repici2013_Article_ParkinsonSDisease_associatedMu.pdf

Involvement of extracellular calcium influx in the self-incompatibility response of Papaver rhoeas.

Autor: Franklin-Tong, Vernonica E., Holdaway-Clarke, Terena L., Straatman, Kornelis R., Kunkel, Joseph G., Hepler, Peter K.

Publikováno v: Plant Journal; Feb2002, Vol. 29 Issue 3, p333-345, 13p

Regulation of post-Golgi LH3 trafficking is essential for collagen homeostasis.

Autor: Banushi B; MRC Laboratory for Molecular Cell Biology, University College London, London WC1E 6BT, UK., Forneris F; Department of Biology and Biotechnology, The Armenise-Harvard Laboratory of Structural Biology, University of Pavia, Via Ferrata 9/A - 27100, Pavia, Italy.; Division of Crystal and Structural Chemistry, Department of Chemistry, Bijvoet Center for Biomolecular Research, Faculty of Science, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands., Straatman-Iwanowska A; MRC Laboratory for Molecular Cell Biology, University College London, London WC1E 6BT, UK., Strange A; Eastman Dental Institute, University College London, London WC1X 8LD, UK., Lyne AM; Department of Statistical Science, University College London, London WC1E 6BT, UK., Rogerson C; MRC Laboratory for Molecular Cell Biology, University College London, London WC1E 6BT, UK., Burden JJ; MRC Laboratory for Molecular Cell Biology, University College London, London WC1E 6BT, UK., Heywood WE; Institute of Child Health, University College London, London WC1N 1EH, UK., Hanley J; Institute of Child Health, University College London, London WC1N 1EH, UK., Doykov I; Institute of Child Health, University College London, London WC1N 1EH, UK., Straatman KR; Centre for Core Biotechnology Services, University of Leicester, Leicester LE1 9HN, UK., Smith H; MRC Laboratory for Molecular Cell Biology, University College London, London WC1E 6BT, UK., Bem D; Centre for Cardiovascular Sciences, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham B152TT, UK., Kriston-Vizi J; MRC Laboratory for Molecular Cell Biology, University College London, London WC1E 6BT, UK., Ariceta G; Department of Pediatric Nephrology, University Hospital Vall d'Hebron, Universitat Autonoma Barcelona, 119-129-08035 Barcelona, Spain., Risteli M; Faculty of Biochemistry and Molecular Medicine, University of Oulu, Aapistie 7B, 90220 Oulu, Finland.; Unit of Cancer Research and Translational Medicine, Faculty of Medicine, University of Oulu, Oulu 90014, Finland.; Medical Research Center Oulu, Oulu University Hospital, University of Oulu, Oulu 90029, Finland., Wang C; Medical Research Center Oulu, Oulu University Hospital, University of Oulu, Oulu 90029, Finland.; Medical Microbiology and Immunology, Unit of Biomedicine, Faculty of Medicine, University of Oulu, Oulu 90014, Finland., Ardill RE; Royal Hospital for Sick Children, Edinburgh EH9 1LF, UK., Zaniew M; Children's Hospital, 61-825 Poznań, Poland., Latka-Grot J; Children's Memorial Health Institute, 04-730 Warsaw, 20 Dzieci Polskich Avenue, Poland., Waddington SN; Institute for Women's Health, University College London, London WC1E 6AU, UK., Howe SJ; Institute for Women's Health, University College London, London WC1E 6AU, UK., Ferraro F; MRC Laboratory for Molecular Cell Biology, University College London, London WC1E 6BT, UK., Gjinovci A; MRC Laboratory for Molecular Cell Biology, University College London, London WC1E 6BT, UK., Lawrence S; MRC Laboratory for Molecular Cell Biology, University College London, London WC1E 6BT, UK., Marsh M; MRC Laboratory for Molecular Cell Biology, University College London, London WC1E 6BT, UK., Girolami M; Department of Statistics, University of Warwick, Coventry CV4 7AL, UK., Bozec L; Eastman Dental Institute, University College London, London WC1X 8LD, UK., Mills K; Institute of Child Health, University College London, London WC1N 1EH, UK., Gissen P; MRC Laboratory for Molecular Cell Biology, University College London, London WC1E 6BT, UK.; Institute of Child Health, University College London, London WC1N 1EH, UK.; Inherited Metabolic Diseases Unit, Great Ormond Street Hospital, London WC1N 3JH, UK.

Publikováno v: Nature communications [Nat Commun] 2016 Jul 20; Vol. 7, pp. 12111. Date of Electronic Publication: 2016 Jul 20.