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Akademický článek

Type I IFN blockade uncouples immunotherapy-induced antitumor immunity and autoimmune toxicity.

Autor: Walsh SR; McMaster Immunology Research Centre, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada., Bastin D; McMaster Immunology Research Centre, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada., Chen L; McMaster Immunology Research Centre, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada., Nguyen A; McMaster Immunology Research Centre, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada., Storbeck CJ; Centre for Innovative Cancer Research, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada., Lefebvre C; Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada., Stojdl D; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada.; Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada., Bramson JL; McMaster Immunology Research Centre, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada., Bell JC; Centre for Innovative Cancer Research, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada., Wan Y; McMaster Immunology Research Centre, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2019 Feb 01; Vol. 129 (2), pp. 518-530. Date of Electronic Publication: 2018 Dec 18.

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Akademický článek

Recruitment and activation of SLK at the leading edge of migrating cells requires Src family kinase activity and the LIM-only protein 4.

Autor: Baron KD; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada., Al-Zahrani K; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada., Conway J; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada., Labrèche C; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada., Storbeck CJ; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada., Visvader JE; Walter and Eliza Hall Institute Biotechnology Centre, Bundoora, Victoria 3086, Australia., Sabourin LA; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Ottawa Hospital Research Institute, Cancer Therapeutics, Ottawa, Ontario, Canada. Electronic address: lsabourin@ohri.ca.

Publikováno v: Biochimica et biophysica acta [Biochim Biophys Acta] 2015 Jul; Vol. 1853 (7), pp. 1683-92. Date of Electronic Publication: 2015 Apr 14.

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Akademický článek

Distinct roles for Ste20-like kinase SLK in muscle function and regeneration.

Autor: Storbeck CJ; Ottawa Hospital Research Institute, 501 Smyth Rd, Box 926, Ottawa, ON K1H8L6, Canada. lsabourin@ohri.ca., Al-Zahrani KN, Sriram R, Kawesa S, O'Reilly P, Daniel K, McKay M, Kothary R, Tsilfidis C, Sabourin LA

Publikováno v: Skeletal muscle [Skelet Muscle] 2013 Jul 01; Vol. 3 (1), pp. 16. Date of Electronic Publication: 2013 Jul 01.

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Akademický článek

The Ldb1 and Ldb2 transcriptional cofactors interact with the Ste20-like kinase SLK and regulate cell migration.

Autor: Storbeck CJ; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada., Wagner S, O'Reilly P, McKay M, Parks RJ, Westphal H, Sabourin LA

Publikováno v: Molecular biology of the cell [Mol Biol Cell] 2009 Oct; Vol. 20 (19), pp. 4174-82. Date of Electronic Publication: 2009 Aug 12.

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Akademický článek

The Ste20-like kinase SLK is required for ErbB2-driven breast cancer cell motility.

Autor: Roovers K; Centre for Cancer Therapeutics, Ottawa Health Research Institute, Ontario, Canada., Wagner S, Storbeck CJ, O'Reilly P, Lo V, Northey JJ, Chmielecki J, Muller WJ, Siegel PM, Sabourin LA

Publikováno v: Oncogene [Oncogene] 2009 Aug 06; Vol. 28 (31), pp. 2839-48. Date of Electronic Publication: 2009 Jun 15.

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Akademický článek

FAK/src-family dependent activation of the Ste20-like kinase SLK is required for microtubule-dependent focal adhesion turnover and cell migration.

Autor: Wagner S; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada., Storbeck CJ, Roovers K, Chaar ZY, Kolodziej P, McKay M, Sabourin LA

Publikováno v: PloS one [PLoS One] 2008 Apr 02; Vol. 3 (4), pp. e1868. Date of Electronic Publication: 2008 Apr 02.

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