Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Stomach Neoplasms / metabolism"'
Autor:
Celso A. Reis, Fátima Gärtner, Joana A. Macedo, Filipe Pinto, Joana Gomes, Diana Campos, Rita Matos, Stefan Mereiter, Marta Pinto, António Polónia, Daniela Freitas, Ana Magalhães
Publikováno v:
EBioMedicine
Background: Changes in glycosylation are known to play critical roles during gastric carcinogenesis. Expression of truncated O-glycans, such as the Sialyl-Tn (STn) antigen, is a common feature shared by many cancers and is associated with cancer aggr
Publikováno v:
Cells
Cells, Vol 9, Iss 2, p 264 (2020)
Volume 9
Issue 2
Cells, Vol 9, Iss 2, p 264 (2020)
Volume 9
Issue 2
CD44 variant isoforms are often upregulated in cancer and associated with increased aggressive tumor phenotypes. The CD44v9 is one of the major protein splice variant isoforms expressed in human gastrointestinal cancer cells. Immunodetection of CD44
Autor:
Carla Oliveira, Maria Sofia Fernandes, Ana Margarida Moreira, Sérgia Velho, Raquel Almeida, Fernando Schmitt, Rita Barros, Joana Paredes, Raquel Seruca, Patrícia Carneiro, Patrícia Oliveira, Anabela Ferro, Joana Figueiredo, Fátima Carneiro
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-13 (2019)
Cell Communication and Signaling : CCS
Cell Communication and Signaling : CCS
Background: E-cadherin has been awarded a key role in the aetiology of both sporadic and hereditary forms of gastric cancer. In this study, we aimed to identify molecular interactors that influence the expression and function of E-cadherin associated
Autor:
Sjoerd Nell, Peter H. Bisschop, Inne H.M. Borel Rinkes, Bas Havekes, Dirk-Jan van Beek, Anouk N A van der Horst-Schrivers, Wouter W. de Herder, Olaf M. Dekkers, Carolina R. C. Pieterman, Madeleine L. Drent, Annenienke C van de Ven, Gerlof D. Valk, Menno R. Vriens
Publikováno v:
Journal of Surgical Oncology, 120(6), 966-975. Wiley
Journal of Surgical Oncology, 120(6), 966. Wiley-Liss Inc.
Journal of Surgical Oncology, 120, 966-975
Journal of Surgical Oncology, 120(6), 966-975. Wiley-Liss Inc.
Journal of Surgical Oncology, 120, 6, pp. 966-975
van Beek, D-J, Nell, S, Pieterman, C R C, de Herder, W W, van de Ven, A C, Dekkers, O M, van der Horst-Schrivers, A N, Drent, M L, Bisschop, P H, Havekes, B, Borel Rinkes, I H M, Vriens, M R & Valk, G D 2019, ' Prognostic factors and survival in MEN1 patients with gastrinomas: Results from the DutchMEN study group (DMSG) ', Journal of Surgical Oncology, vol. 120, no. 6, pp. 966-975 . https://doi.org/10.1002/jso.25667
Journal of surgical oncology, 120(6), 966-975. Wiley-Liss Inc.
Journal of Surgical Oncology, 120(6), 966-975. WILEY
Journal of Surgical Oncology. Wiley-Liss Inc.
Journal of Surgical Oncology
Journal of Surgical Oncology, 120(6), 966. Wiley-Liss Inc.
Journal of Surgical Oncology, 120, 966-975
Journal of Surgical Oncology, 120(6), 966-975. Wiley-Liss Inc.
Journal of Surgical Oncology, 120, 6, pp. 966-975
van Beek, D-J, Nell, S, Pieterman, C R C, de Herder, W W, van de Ven, A C, Dekkers, O M, van der Horst-Schrivers, A N, Drent, M L, Bisschop, P H, Havekes, B, Borel Rinkes, I H M, Vriens, M R & Valk, G D 2019, ' Prognostic factors and survival in MEN1 patients with gastrinomas: Results from the DutchMEN study group (DMSG) ', Journal of Surgical Oncology, vol. 120, no. 6, pp. 966-975 . https://doi.org/10.1002/jso.25667
Journal of surgical oncology, 120(6), 966-975. Wiley-Liss Inc.
Journal of Surgical Oncology, 120(6), 966-975. WILEY
Journal of Surgical Oncology. Wiley-Liss Inc.
Journal of Surgical Oncology
Contains fulltext : 215696.pdf (Publisher’s version ) (Open Access) BACKGROUND AND OBJECTIVES: Gastrinomas are the most prevalent functioning neuroendocrine tumors (NET) in multiple endocrine neoplasia type 1 (MEN1). Guidelines suggest medical ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3423a512d6ed3bf3a34818ba6d1380ad
https://research.rug.nl/en/publications/c0caf693-e326-4e4c-bda1-502050b2467d
https://research.rug.nl/en/publications/c0caf693-e326-4e4c-bda1-502050b2467d
Autor:
Joana Carvalho, Sara Pinto Teles, Carla Oliveira, Patrícia Oliveira, Mafalda Azevedo, Sara Rocha
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2608 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 11
International Journal of Molecular Sciences
Volume 20
Issue 11
Extracellular vesicles (EVs) secreted by tumor cells modulate recipient cells&rsquo
behavior, but their effects in normal cells from the tumor microenvironment remain poorly known. In this study, we dissected the functional impact of gastric can
behavior, but their effects in normal cells from the tumor microenvironment remain poorly known. In this study, we dissected the functional impact of gastric can
Autor:
Paula Boaventura, Patrícia Mesquita, Luísa Pereira, Nair Lopes, Helena Pópulo, Ana Filipa Freire, Daniela Azevedo, Bruno Cavadas, Rita Barros, Bruno Pereira, Leonor David, Raquel Almeida, Rosa Gomes
Publikováno v:
Disease Markers, Vol 2019 (2019)
Disease Markers
Disease Markers
Gastric cancer is one of the most frequent tumours and the third leading cause of cancer-related death worldwide. The investigation of new biomarkers that can predict patient outcome more accurately and allow better treatment and follow-up decisions
Autor:
Fátima Carneiro, Michael Pierce, Celso A. Reis, Raquel Seruca, Sandra Carvalho, Markus F. Bartels, Eiji Miyoshi, Tiago Oliveira, Sabine Strahl, Salomé S. Pinho, Naoyuki Taniguchi
Publikováno v:
Oncotarget
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
// Sandra Carvalho 1, 2, * , Tiago Oliveira 1, * , Markus F. Bartels 3 , Eiji Miyoshi 4 , Michael Pierce 5 , Naoyuki Taniguchi 6 , Fatima Carneiro 1, 7, 8 , Raquel Seruca 1, 8 , Celso A. Reis 1, 2, 8 , Sabine Strahl 3 , Salome S. Pinho 1, 7 1 Institu
Autor:
Meritxell Balmaña, Francisca Diniz, Tália Feijão, Celso A. Reis, Stefan Mereiter, Cristina C. Barrias
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 21; Issue 3; Pages: 722
International Journal of Molecular Sciences, Vol 21, Iss 3, p 722 (2020)
International Journal of Molecular Sciences; Volume 21; Issue 3; Pages: 722
International Journal of Molecular Sciences, Vol 21, Iss 3, p 722 (2020)
In the scenario of personalized medicine, targeted therapies are currently the focus of cancer drug development. These drugs can block the growth and spread of tumor cells by interfering with key molecules involved in malignancy, such as receptor tyr
Autor:
Raquel Seruca, Joao Sanches, Joana Figueiredo, Soraia Melo, Kimberley Gamet, Susana Seixas, Parry Guilford, Tanis D Godwin
Publikováno v:
Molecular Cancer
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Molecular Cancer, Vol 17, Iss 1, Pp 1-7 (2018)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Molecular Cancer, Vol 17, Iss 1, Pp 1-7 (2018)
The aim of this study was to uncover the pathogenic relevance and the underlying molecular mechanism of a novel CDH1 variant found in a Hereditary Diffuse Gastric Cancer family (p.L13_L15del), which affects the signal peptide of E-cadherin without ch
Autor:
Soraia Melo, Maria Sofia Fernandes, Joana Paredes, Joao Sanches, Joana Figueiredo, Raquel Seruca, Bárbara Sousa, Isabel Rodrigues, João Ribeiro
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Immunofluorescence is the gold standard technique to determine the level and spatial distribution of fluorescent-tagged molecules. However, quantitative analysis of fluorescence microscopy images faces crucial challenges such as morphologic variabili