Methylation cytometric pretreatment blood immune profiles with tumor mutation burden as prognostic indicators for survival outcomes in head and neck cancer patients on anti-PD-1 therapy.

Autor: Zhang Z; Department of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA. ze.zhang.gr@dartmouth.edu.; Dartmouth Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA. ze.zhang.gr@dartmouth.edu., Sehgal K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Shirai K; Dartmouth Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA., Butler RA; Department of Epidemiology, School of Public Health, Brown University, Providence, RI, USA.; Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA., Wiencke JK; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA., Koestler DC; Department of Biostatistics & Data Science, University of Kansas Medical Center, Kansas City, KS, USA., Ramush G; Department of Epidemiology, School of Public Health, Brown University, Providence, RI, USA.; Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA., Lee MK; Department of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.; Dartmouth Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA., Molinaro AM; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA., Stolrow HG; Department of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.; Dartmouth Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA., Birnbaum A; Department of Medicine, Rhode Island Hospital, Providence, RI, USA., Salas LA; Department of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.; Dartmouth Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA., Haddad RI; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Kelsey KT; Department of Epidemiology, School of Public Health, Brown University, Providence, RI, USA.; Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA., Christensen BC; Department of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.; Dartmouth Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.

Publikováno v: NPJ precision oncology [NPJ Precis Oncol] 2024 Nov 18; Vol. 8 (1), pp. 267. Date of Electronic Publication: 2024 Nov 18.

Down Syndrome Altered Cell Composition in Blood, Brain, and Buccal Swab Samples Profiled by DNA-Methylation-Based Cell-Type Deconvolution.

Autor: Zhang Z; Department of Epidemiology, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756, USA., Stolrow HG; Department of Epidemiology, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756, USA., Christensen BC; Department of Epidemiology, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756, USA.; Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756, USA., Salas LA; Department of Epidemiology, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756, USA.; Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756, USA.

Publikováno v: Cells [Cells] 2023 Apr 15; Vol. 12 (8). Date of Electronic Publication: 2023 Apr 15.