Endothelial dysfunction in neurodegenerative disease: Is endothelial inflammation an overlooked druggable target?

Autor: Ritson M; Department of Comparative Biomedical Sciences, Royal Veterinary College, London NW1 0TU, UK., Wheeler-Jones CPD; Department of Comparative Biomedical Sciences, Royal Veterinary College, London NW1 0TU, UK., Stolp HB; Department of Comparative Biomedical Sciences, Royal Veterinary College, London NW1 0TU, UK. Electronic address: hstolp@rvc.ac.uk.

Publikováno v: Journal of neuroimmunology [J Neuroimmunol] 2024 Jun 15; Vol. 391, pp. 578363. Date of Electronic Publication: 2024 May 03.

Montelukast reduces grey matter abnormalities and functional deficits in a mouse model of inflammation-induced encephalopathy of prematurity.

Autor: Yates AG; Centre for the Developing Brain, School of Biomedical Engineering & Imaging Sciences, King's College London, London, UK.; Icahn School of Medicine at Mount Sinai, New York, NY, USA., Kislitsyna E; Centre for the Developing Brain, School of Biomedical Engineering & Imaging Sciences, King's College London, London, UK., Alfonso Martin C; Centre for the Developing Brain, School of Biomedical Engineering & Imaging Sciences, King's College London, London, UK., Zhang J; Centre for the Developing Brain, School of Biomedical Engineering & Imaging Sciences, King's College London, London, UK., Sewell AL; Centre for the Developing Brain, School of Biomedical Engineering & Imaging Sciences, King's College London, London, UK., Goikolea-Vives A; Comparative Biomedical Sciences, Royal Veterinary College, Royal College Street, London, NW1 0TU, UK., Cai V; Comparative Biomedical Sciences, Royal Veterinary College, Royal College Street, London, NW1 0TU, UK., Alkhader LF; Centre for the Developing Brain, School of Biomedical Engineering & Imaging Sciences, King's College London, London, UK., Skaland A; Centre for the Developing Brain, School of Biomedical Engineering & Imaging Sciences, King's College London, London, UK., Hammond B; Centre for the Developing Brain, School of Biomedical Engineering & Imaging Sciences, King's College London, London, UK., Dimitrova R; Centre for the Developing Brain, School of Biomedical Engineering & Imaging Sciences, King's College London, London, UK.; Department of Forensic and Neurodevelopmental Science, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Batalle D; Centre for the Developing Brain, School of Biomedical Engineering & Imaging Sciences, King's College London, London, UK.; Department of Forensic and Neurodevelopmental Science, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Fernandes C; SGDP Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; MRC Centre for Neurodevelopment Disorders, King's College London, London, UK., Edwards AD; Centre for the Developing Brain, School of Biomedical Engineering & Imaging Sciences, King's College London, London, UK., Gressens P; Université Paris Cité, Inserm, NeuroDiderot, Paris, France., Thornton C; Centre for the Developing Brain, School of Biomedical Engineering & Imaging Sciences, King's College London, London, UK.; Comparative Biomedical Sciences, Royal Veterinary College, Royal College Street, London, NW1 0TU, UK., Stolp HB; Centre for the Developing Brain, School of Biomedical Engineering & Imaging Sciences, King's College London, London, UK. hstolp@rvc.ac.uk.; Comparative Biomedical Sciences, Royal Veterinary College, Royal College Street, London, NW1 0TU, UK. hstolp@rvc.ac.uk.

Publikováno v: Journal of neuroinflammation [J Neuroinflammation] 2022 Oct 29; Vol. 19 (1), pp. 265. Date of Electronic Publication: 2022 Oct 29.

T₂-weighted MRI detects presymptomatic pathology in the SOD1 mouse model of ALS

Autor: Evans, MC, Serres, S, Khrapitchev, AA, Stolp, HB, Anthony, DC, Talbot, K, Turner, MR, Sibson, NR

Neuroinflammation has been identified as a potential therapeutic target in amyotrophic lateral sclerosis (ALS), but relevant biomarkers are needed. The superoxide dismutase (SOD1)(G93A) transgenic mouse model of ALS offers a unique opportunity to stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::90961ee8ea30b137676d49293e405480
https://doi.org/10.1038/jcbfm.2014.19

CNS-TARGETED METHYLPREDNISOLONE REDUCES PATHOLOGY IN MOUSE MODEL OF ALS

Autor: Stolp, HB, Evans, MC, Gaillard, P, de Boer, M, Appeldoorn, C, Dorland, R, Sibson, NR, Turner, MR, Anthony, DC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0bf3d83403f63f3c3e33373c432bde05
https://ora.ox.ac.uk/objects/uuid:7d1b9d9b-b1fa-4fe5-b36f-90e5c9cc40c9

Aging alters the expression of trophic factors and tight junction proteins in the mouse choroid plexus.

Autor: Sadanandan, Jayanarayanan¹ (AUTHOR), Sathyanesan, Monica¹ (AUTHOR), Newton, Samuel S.¹ (AUTHOR) samuel.sathyanesan@usd.edu

Publikováno v: Fluids & Barriers of the CNS. 9/27/2024, Vol. 21 Issue 1, p1-19. 19p.