Surgery and outcome of infective endocarditis in octogenarians: prospective data from the ESC EORP EURO-ENDO registry

Autor: Pazdernik, Michal, Iung, Bernard, Mutlu, Bulent, Alla, François, Riezebos, Robert, Kong, William, Nunes, Maria Carmo Pereira, Pierard, Luc, Srdanovic, Ilija, Yamada, Hirotsugu, de Martino, Andrea, Miglioranza, Marcelo Haertel, Magne, Julien, Piper, Cornelia, Laroche, C. cile, Maggioni, Aldo P., Lancellotti, Patrizio, Habib, Gilbert, Selton-Suty, Christine, Ronderos, R., Avegliano, G., Oses, P. Fernandez, Filipini, E., Granada, I., Iribarren, A., Mahia, M., Nacinovich, F., Ressi, S., Obregon, R., Bangher, M., Dho, J., Cartasegna, L., Plastino, M. L., Novas, V., Shigel, C., Reyes, G., de Santos, M., Gastaldello, N., Fernandez, M. Granillo, Potito, M., Streitenberger, G., Velazco, P., Casabé, J. H., Cortes, C., Guevara, E., Salmo, F., Seijo, M., Weidinger, F., Heger, M., Brooks, R., Stöllberger, C., Ho, C. Y., Perschy, L., Puskas, L., Goliasch, G., Binder, C., Rosenhek, R., Schneider, M., Winter, M. P., Hoffer, E., Melissopoulou, M., Lecoq, E., Legrand, D., Jacquet, S., Massoz, M., Lancellotti, P., Pierard, L., Dulgheru, R., Marchetta, S., D´Emal, C., Oury, C., Cosyns, B., Droogmans, S., Kerkhove, D., Motoc, A., Plein, D., Roosens, B., Soens, L., Weytjens, C., Lemoine, I., Rodrigus, I., Paelinck, B., Amsel, B., Unger, P., Konopnicki, D., Beauloye, C., Pasquet, A., Pierard, S., Vancraeynest, D., Vanoverschelde, J. L., Sinnaeve, F., Andrade, J. L., Rodrigues, A. C. Tude, Staszko, K., Dos Santos Monteiro, R., Miglioranza, M. H., Shuha, D. L., Alcantara, M., Cravo, V., Fazzio, L., Felix, A., Iso, M., Musa, C., Siciliano, A. P., Filho, F. Villaca, Braga, J., Rodrigues, A., Silva, R., Vilela, F., Rodrigues, D., Silva, L., Morhy, S., Fischer, C., Vieira, M., Afonso, T., Abreu, J., Falcao, S. N., Moises, V., Gouvea, A., João, G., Mancuso, F., Silva, C., Souza, A. C., Abboud, C. S., de Mattos Barretto, R. Bellio, Ramos, A., Arnoni, R., Assef, J. E., Togna, D. J. Della, le Bihan, D., Miglioli, L., Oliveira, A. P. Romero, Kroll, R. Tadeu Magro, Cortez, D., Gelape, C. L., Nunes, M. d. C. Peirira, de Abreu Ferrari, T. C., Chan, K. L., Hay, K., le, V., Page, M., Poulin, F., Sauve, C., Serri, K., Mercure, C., Beaudoin, J., Pibarot, P., Sebag, I., Rudski, L., Ricafort, G., Barsic, B., Krajinovic, V., Vargovic, M., Separovic-Hanzevacki, J., Lovric, D., Reskovic-Luksic, V., Vincelj, J., Jurinjak, S. Jaksic, Yiannikourides, V., Ioannides, M., Kyriakou, C., Pofaides, C., Masoura, V., Yiangou, K., Pudich, J., Linhart, A., Siranec, M., Marek, J., Blechova, K., Kamenik, M., Pazdernik, M., Pelouch, R., Coufal, Z., Mikulica, M., Griva, M., Jancova, E., Mikulcova, M., Taborsky, M., Precek, J., Jecmenova, M., Latal, J., Widimsky, J., Butta, T., Machacek, S., Vancata, R., Spinar, J., Holicka, M., Long, F. Pow Chon, Anzules, N., Carpio, A. Bajana, Largacha, G., Penaherrera, E., Moreira, D., Mahfouz, E., Elsafty, E., Soliman, A., Zayed, Y., Aboulenein, J., Abdel-Hay, M., Almaghraby, A., Abdelnaby, M., Ahmed, M., Hammad, B., Saleh, Y., Zahran, H., Elgebaly, O., Saad, A., Ali, M., Zeid, A., Sharkawy, R. El, Meshaal, M., Al Kholy, A., Doss, R., Osama, D., Rizk, H., Elmogy, A., Mishriky, M., Assayag, P., Hatimi, S. El, Botelho-Nevers, Saint- E., Campisi, S., Fuzellier, J. F., Gagneux-Brunon, A., Pierrard, R., Tulane, C., Detoc, M., Mehalla, T., Boutoille, D., Al Habash, O., Asseray-Madani, N., Biron, C., Brochard, J., Caillon, J., Cueff, C., le Tourneau, T., Lecompte, A. S., Lecomte, R., Lefebvre, M., Michel, M. M. Magali, Pattier, S., Delarue, S., le Bras, M., Orain, J., Faucher, J. F., Aboyans, V., Beeharry, A., Durox, H., Lacoste, M., Magne, J., Mohty, D., David, A., Pradel, V., Sierra, V., Neykova, A., Bettayeb, B., Elkentaoui, S., Tzvetkov, B., Landry, G., Strady, C., Ainine, K., Baumard, S., Brasselet, C., Tassigny, C., Valente-Pires, V., Lefranc, M., Hoen, B., Lefevre, B., Curlier, E., Callier, C., Fourcade, N., Jobic, Y., Ansard, S., le Berre, R., le Roux, P., le Ven, F., Pouliquen, M. C., Prat, G., Bouchart, F., Savoure, A., Alarcon, C., Chapuzet, C., Gueit, I., Tribouilloy, C., Bohbot, Y., Peugnet, F., Gun, M., Iung, B., Duval, X., Lescure, X., Ilic-Habensus, E., Sadoul, N., Selton-Suty, C., Alla, F., Chevalier, E., Goehringer, F., Huttin, O., Garcia, R., le Marcis, V., Tattevin, P., Donal, E., Flecher, E., Revest, M., Habib, G., Hubert, S., Casalta, J. P., Gouriet, F., Arregle, F., Cammilleri, S., Tessonnier, L., Riberi, A., Chirouze, C., Bouiller, K., Brunel, A. S., Fournier, D., Hustache-Mathieu, L., Klopfenstein, T., Moreau, J., Lim, P., Oliver, L., Ternacle, J., Moussafeur, A., Chavanet, P., Piroth, L., Buisson, M., Mahy, S., Martins, C., Salmon-Rousseau, A., Gohier, S., Piper, C., Börgermann, J., Guckel, D., Horstkotte, D., Brockmeier, B., Winkelmann, E., Hagendorff, A., Grey, D., Nickenig, G., Schueler, R., Öztürk, C., Stöhr, E., Hamm, C., Walther, T., Brandt, R., Frühauf, A. C., Hartung, C. T., Hellner, C., Wild, C., Becker, M., Hamada, S., Kaestner, W., Stangl, K., Knebel, F., Baldenhofer, G., Brecht, A., Dreger, H., Isner, C., Pfafflin, F., Stegemann, M., Zahn, R., Fraiture, B., Kilkowski, C., Karcher, A. K., Klinger, S., Tolksdorf, H., Tousoulis, D., Aggeli, C., Sarri, G., Sideris, S., Venieri, E., Athanassopoulos, G., Tsiapras, D., Armenis, I., Koutsiari, A., Floros, G., Grassos, C., Dragasis, S., Rallidis, L., Varlamos, C., Michalis, L., Naka, K., Bechlioulis, A., Kotsia, A., Lakkas, L., Pappas, K., Papadopoulos, C., Kiokas, S., Lioni, A., Misailidou, S., Barbetseas, J., Bonou, M., Kapelios, C., Tomprou, I., Zerva, K., Manolis, A., Hamodraka, E., Athanasiou, D., Haralambidis, G., Poulimenos, L., Samaras, H., Nagy, A., Bartykowszki, A., Gara, E., Sengupta, S., Mungulmare, K., Kasliwal, R., Bansal, M., Bhan, A., Ranjan, S., Kyavar, M., Maleki, M., Bezanjani, F. Noohi, Sadeghpour, A., Alizadehasl, A., Boudagh, S., Ghavidel, A., Moradnejad, P., Pasha, H. R., Ghadrdoost, B., Gilon, D., Strahilevitz, J., Israel, S., Wanounou, M., d’Agostino, C., Colonna, P., de Michele, L., Fumarola, F., Stante, M., Marchionni, N., Scheggi, V., Alterini, B., del Pace, S., Stefano, P., Sparano, C., Badano, L. P., Muraru, D., Ruozi, N., Tenaglia, R., Limbruno, U., Cresti, A., Baratta, P., Solari, M., Giannattasio, C., Moreo, A., de Chiara, B., Montero, B. Lopez, Musca, F., Orcese, C. A., Panzeri, F., Russo, C. F., Spano, F., Alfieri, O., de Bonis, M., Agricola, E., Busnardo, E., Carletti, S., Castiglioni, B., Chiappetta, S., del Forno, B., Ferrara, D., Guffanti, M., Iaci, G., Lapenna, E., Nisi, T., Oltolini, C., Pajoro, U., Pasciuta, R., Ripa, M., Scarpellini, P., Din, C. Tassan, Meneghin, R., Schiavi, D., Piscione, F., Citro, R., Benvenga, R. M., Greco, L., Prota, C., Radano, I., Soriente, L., Bellino, M., di Vece, D., Santini, F., Salsano, A., Olivieri, G. M., Turrini, F., Messora, R., Tondi, S., Olaru, A., Agnoletto, V., Grassi, L., Leonardi, C., Sansoni, S., del Ponte, S., Dato, G. M. Actis, de Martino, A., Ohte, N., Kikuchi, S., Wakami, K., Aonuma, K., Seo, Y., Ishizu, T., Machino-Ohtsuka, T., Yamamoto, M., Iida, N., Nakajima, H., Nakagawa, Y., Izumi, C., Amano, M., Miyake, M., Takahashi, K., Shiojima, I., Miyasaka, Y., Maeba, H., Suwa, Y., Taniguchi, N., Tsujimoto, S., Kitai, T., Ota, M., Yuda, S., Sasaki, S., Hagiwara, N., Yamazaki, K., Ashihara, K., Arai, K., Saitou, C., Saitou, S., Suzuki, G., Shibata, Y., Watanabe, N., Nishino, S., Ashikaga, K., Kuriyama, N., Mahara, K., Abe, K., Fujimaki, H., Okubo, T., Shitan, H., Takanashi, S., Terada, M., Yamamoto, H., Sata, M., Yamada, H., Kusunose, K., Saijo, Y., Seno, H., Yuichiro, O., Sakata, Y., Mizuno, H., Nakatani, S., Onishi, T., Sengoku, K., Sera, F., Park, S. W., Kyoung, K. Eun, Yeon, L. Ga, Hwang, J. W., Jin-Oh, C., Park, S. J., Sang-Chol, L., Sung-A, C., Jang, S. Y., Kang, D. H., Heo, R., Lee, S., Song, J. M., Jung, E., Plisiene, J., Dambrauskaite, A., Gruodyte, G., Jonkaitiene, R., Vaskelyte, J., Mizariene, V., Atkocaityte, J., Zvirblyte, R., Sow, R., Codreanu, A., de la Vega, E. C. L., Michaux, C., Staub, T., Jacobs-Orazi, L., Azzopardi, C. Mallia, Xuereb, R. G., Piscopo, T., Borg, D., Casha, R., Farrugia, J., Fenech, M., Pllaha, E., Vella, C., Yamagata, K., Grib, L., Raevschi, E., Grejdieru, A., Balan, G., Cardaniuc, I., Cardaniuc, L., Corcea, V., Feodorovici, A., Gaina, V., Girbu, L., Jimbei, P., Kravcenco, D., Panfile, E., Prisacari, E., Samohvalov, E., Samohvalov, S., Sceglova, N., Benesco, I., Marian, V., Sumarga, N., Mirocevic, M., Bozovic, B., Bulatovic, N., Lakovic, P., Music, L., Roos-Hesselink, J., Budde, R., Gamela, T., Wahadat, A., Kamp, O., Meijers, T., van Melle, J. P., Deursen, V. M., Crijns, H., Bekkers, S., Cheriex, E., Gilbers, M., Kietselaer, B., Knackstedt, C., Lorusso, R., Schalla, S., Streukens, S., Chamuleau, S., Cramer, M. J., Teske, A., van der Spoel, T., Wind, A., Liesbek, O., Lokhorst, J., van Heusden, H., Tanis, W., van der Bilt, I., Vriend, J., de Lange-van Bruggen, H., Karijodikoro, E., Riezebos, R., van Dongen, E., Schoep, J., Stolk, V., Axler, O., Baumann, F., Lebras, S., Edvardsen, T., Offstad, J. T., Beitnes, J. O., Helle-Valle, T., Skulstad, H., Skardal, R., Qamar, N., Furnaz, S., Ahmed, B., Butt, M. H., Khanzada, M. F., Saghir, T., Wahid, A., Hryniewiecki, T., Szymanski, P., Marzec, K., Misztal-Ogonowska, M., Kosmala, W., Przewlocka-Kosmala, M., Rojek, A., Woznicka, K., Zachwyc, J., Lisowska, A., Kaminska, M., Kasprzak, J., Kowalczyk, E., Strzecka, D. F., Wejner-Mik, P., Trabulo, M., Freitas, P., Ranchordas, S., Rodrigues, G., Pinto, P., Queiros, C., Azevedo, J., Marques, L., Seabra, D., Branco, L., Cruz, M., Galrinho, A., Moreira, R., Rio, P., Timoteo, A. T., Selas, M., Cardim, N. M., Carmelo, V., Neves, B. Duque, Pereira, H., Cruz, I., Guerra, A., Marques, A., Pintassilgo, I., Tomescu, M. C., Trofenciuc, N. M., Andor, M., Bordejevic, A., Branea, H. S., Caruntu, F., Cirin, L., Citu, I. M., Cotoraci, C. A., Darabantiu, D., Farcas, R., Marincu, I., Mavrea, A., Onel, M. F., Parvanescu, T., Pop, D., Pop-Moldovan, A. L., Puticiu, M. I., Velcean, L. A., Ionac, A., Cozma, D., Mornos, C., Goanta, F., Popescu, I., Beyer, R., Mada, R., Rancea, R., Rosianu, H., Tomoaia, R., Stanescu, C., Kobalava, Z., Karaulova, J., Kotova, E., Milto, A., Pisaryuk, A., Povalyaev, N., Sorokina, M., Alrahimi, J., Elshiekh, A., Jamiel, A., Ahmed, A., Al-Mallah, M., Attia, N., Putnikovic, B., Neskovic, A., Dimic, A., Ivanovic, B., Matic, S., Trifunovic, D., Petrovic, J., Kosevic, D., Dabic, P., Milojevic, P., Petrovic, I., Stojanovic, I., Srdanovic, I., Kovacevic, M., Redzek, A., Stefanovic, M., Susak, S., Velicki, L., Vulin, A., Yeo, T. C., Kong, W. K. F., Poh, K. K., Vilacosta, I., Nasser, M. Abd El, Ferrera, C., Olmos, C., Iglesias, F. Calvo, Blanco-Gonzalez, E., Amaro, M. Bravo, Germinas, A. 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Publikováno v: Infection, 50(5), 1191-1202. Urban und Vogel
Pazdernik, M, Iung, B, Mutlu, B, Alla, F, Riezebos, R, Kong, W, Nunes, M C P, Pierard, L, Srdanovic, I, Yamada, H, de Martino, A, Miglioranza, M H, Magne, J, Piper, C, Laroche, C C, Maggioni, A P, Lancellotti, P, Habib, G, Selton-Suty, C, the EURO-ENDO Investigators group, Ronderos, R, Avegliano, G, Oses, P F, Filipini, E, Granada, I, Iribarren, A, Mahia, M, Nacinovich, F, Ressi, S, Obregon, R, Bangher, M, Dho, J, Cartasegna, L, Plastino, M L, Novas, V, Shigel, C, Reyes, G, de Santos, M, Gastaldello, N, Fernandez, M G, Potito, M, Streitenberger, G, Velazco, P, Casabé, J H, Cortes, C, Guevara, E, Salmo, F, Seijo, M, Weidinger, F, Heger, M, Brooks, R, Stöllberger, C, Ho, C Y, Perschy, L, Puskas, L, Goliasch, G, Binder, C, Rosenhek, R, Schneider, M, Winter, M P, Hoffer, E, Melissopoulou, M, Lecoq, E, Legrand, D, Jacquet, S, Massoz, M, Lancellotti, P, Pierard, L, Dulgheru, R, Marchetta, S, D´Emal, C, Oury, C, Cosyns, B, Droogmans, S, Kerkhove, D, Motoc, A, Plein, D, Roosens, B, Soens, L, Weytjens, C, Lemoine, I, Rodrigus, I, Paelinck, B, Amsel, B, Unger, P, Konopnicki, D, Beauloye, C, Pasquet, A, Pierard, S, Vancraeynest, D, Vanoverschelde, J L, Sinnaeve, F, Andrade, J L, Rodrigues, A C T, Staszko, K, Dos Santos Monteiro, R, Miglioranza, M H, Shuha, D L, Alcantara, M, Cravo, V, Fazzio, L, Felix, A, Iso, M, Musa, C, Siciliano, A P, Filho, F V, Braga, J, Rodrigues, A, Silva, R, Vilela, F, Rodrigues, D, Silva, L, Morhy, S, Fischer, C, Silva, R, Vieira, M, Afonso, T, Abreu, J, Falcao, S N, Moises, V, Gouvea, A, João, G, Mancuso, F, Silva, C, Souza, A C, Abboud, C S, de Mattos Barretto, R B, Ramos, A, Arnoni, R, Assef, J E, Togna, D J D, le Bihan, D, Miglioli, L, Oliveira, A P R, Kroll, R T M, Cortez, D, Gelape, C L, Nunes, M D C P, de Abreu Ferrari, T C, Chan, K L, Hay, K, le, V, Page, M, Poulin, F, Sauve, C, Serri, K, Mercure, C, Beaudoin, J, Pibarot, P, Sebag, I, Rudski, L, Ricafort, G, Barsic, B, Krajinovic, V, Vargovic, M, Separovic-Hanzevacki, J, Lovric, D, Reskovic-Luksic, V, Vincelj, J, Jurinjak, S J, Yiannikourides, V, Ioannides, M, Kyriakou, C, Pofaides, C, Masoura, V, Yiangou, K, Pudich, J, Linhart, A, Siranec, M, Marek, J, Blechova, K, Kamenik, M, Pazdernik, M, Pelouch, R, Coufal, Z, Mikulica, M, Griva, M, Jancova, E, Mikulcova, M, Taborsky, M, Precek, J, Jecmenova, M, Latal, J, Widimsky, J, Butta, T, Machacek, S, Vancata, R, Spinar, J, Holicka, M, Long, F P C, Anzules, N, Carpio, A B, Largacha, G, Penaherrera, E, Moreira, D, Mahfouz, E, Elsafty, E, Soliman, A, Zayed, Y, Aboulenein, J, Abdel-Hay, M, Almaghraby, A, Abdelnaby, M, Ahmed, M, Hammad, B, Saleh, Y, Zahran, H, Elgebaly, O, Saad, A, Ali, M, Zeid, A, Sharkawy, R E, Meshaal, M, Al Kholy, A, Doss, R, Osama, D, Rizk, H, Elmogy, A, Mishriky, M, Assayag, P, Hatimi, S E, Botelho-Nevers, S E, Campisi, S, Fuzellier, J F, Gagneux-Brunon, A, Pierrard, R, Tulane, C, Detoc, M, Mehalla, T, Boutoille, D, Al Habash, O, Asseray-Madani, N, Biron, C, Brochard, J, Caillon, J, Cueff, C, le 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Slama, I, Gulel, O, Sahin, M, Sade, L E, Karacaglar, E, Kucukoglu, S, Cetinarslan, O, Yasar, U S, Canpolat, U, Mutlu, B, Atas, H, Dervishova, R, Ileri, C, Zaky, H, Alhashmi, J, Baslib, F, Tahir, J, Zarger, P, Woldman, S, Menezes, L, Primus, C, Uppal, R, Bvekerwa, I, Chandrasekaran, B, Kopanska, A, Prendergast, B, Cannata, S, Chambers, J, Hancock, J, Klein, J, Rajani, R, Ursi, M P, Dworakowski, R, Fife, A, Breeze, J, Browne-Morgan, M, Gunning, M, Streather, S, Asch, F, Zemedkun, M, Alyavi, B & Uzokov, J 2022, ' Surgery and outcome of infective endocarditis in octogenarians : prospective data from the ESC EORP EURO-ENDO registry ', Infection, vol. 50, no. 5, pp. 1191-1202 . https://doi.org/10.1007/s15010-022-01792-0
Infection
Infection, 2022, ⟨10.1007/s15010-022-01792-0⟩

Purpose: High mortality and a limited performance of valvular surgery are typical features of infective endocarditis (IE) in octogenarians, even though surgical treatment is a major determinant of a successful outcome in IE. Methods: Data from the pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0339f01991f197c39f8795963d528b8
https://research.vumc.nl/en/publications/7d957c66-0fe3-4200-9115-e799c8b9de2a

Socio-Economic Variations Determine the Clinical Presentation, Aetiology and Outcome of Infective Endocarditis: a Prospective Cohort Study from the ESC-EORP EURO-ENDO (European Infective Endocarditis) Registry

Autor: Sengupta, Shantanu P, Prendergast, Bernard, Laroche, Cécile, Furnaz, Shumaila, Ronderos, Ricardo, Almaghraby, Abdallah, Asch, Federico M, Blechova, Kamila, Zaky, Hosam, Strahilevitz, Jacob, Dworakowski, Rafal, Miyasaka, Yoko, Sebag, Igal, Izumi, Chisato, Axler, Olivier, Jamiel, Abdulrahman, Philip, Mary, Campos Vieira, Marcelo Luiz, Lancellotti, Patrizio, Habib, Gilbert, P Gale, C, Beleslin, B, Budaj, A, Chioncel, O, Dagres, N, Danchin, N, Emberson, J, Erlinge, D, Glikson, M, Gray, A, Kayikcioglu, M, P Maggioni, A, K Nagy, V, Nedoshivin, A, A-S, Petronio, Roos-Hesselink, J, Wallentin, L, Zeymer, U, Habib, G, Lancellotti, P, Cosyns, B, Donal, E, Erba, P, Iung, B, A Popescu, B, Prendergast, B, Tornos, P, Andarala, M, Berle, C, Brunel-Lebecq, A, Fiorucci, E, Laroche, C, Missiamenou, V, Taylor, C, N Ali Tatar-Chentir, N, Al-Mallah, M, M Astrom Aneq, Athanassopoulos, G, P Badano, L, Benyoussef, S, E Calderon Aranda, M Cardim, N, K-L, Chan, Cruz, I, Edvardsen, T, Goliasch, G, Hagendorff, A, Hristova, K, Kamp, O, D-H, Kang, Kong, W, Matskeplishvili, S, Meshaal, M, Mirocevic, M, N Neskovic, A, Pazdernik, M, Plonska-Gosciniak, E, Raissouni, M, Ronderos, R, E Sade, L, Sadeghpour, A, Sambola, A, Sengupta, S, Separovic-Hanzevacki, J, Takeuchi, M, Tucay, E, C Tude Rodrigues, A, Varga, A, Vaskelyte, J, Yamagata, K, Yiangou, K, Zaky, H, Granada, I, Mahia, M, Ressi, S, Nacinovich, F, Iribarren, A, P Fernandez Oses, Avegliano, G, Filipini, E, Obregon, R, Bangher, M, Dho, J, Cartasegna, L, L Plastino, M, Novas, V, Shigel, C, Reyes, G, M De Santos, Gastaldello, N, M Granillo Fernandez, Potito, M, Streitenberger, G, Velazco, P, H Casabé, J, Cortes, C, Guevara, E, Salmo, F, Seijo, M, Weidinger, F, Heger, M, Brooks, R, Stöllberger, C, C-Y, Ho, Perschy, L, Puskas, L, Binder, C, Rosenhek, R, Schneider, M, M-P, Winter, Hoffer, E, Melissopoulou, M, Lecoq, E, Legrand, D, Jacquet, S, Massoz, M, Pierard, L, Marchetta, S, Dulgheru, R, D Emal, C, Oury, C, Droogmans, S, Kerkhove, D, 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Atkocaityte, J, Zvirblyte, R, Sow, R, Codreanu, A, Staub, T, Michaux, C, E C, L De la Vega, Jacobs-Orazi, L, C Mallia Azzopardi, G Xuereb, R, Piscopo, T, Farrugia, J, Fenech, M, Pllaha, E, Vella, C, Borg, D, Casha, R, Grib, L, Raevschi, E, Grejdieru, A, Kravcenco, D, Prisacari, E, Samohvalov, E, Samohvalov, S, Sceglova, N, Panfile, E, Cardaniuc, L, Corcea, V, Feodorovici, A, Gaina, V, Girbu, L, Jimbei, P, Balan, G, Cardaniuc, I, Benesco, I, Marian, V, Sumarga, N, Bozovic, B, Bulatovic, N, Lakovic, P, Music, L, Budde, R, Wahadat, A, Gamela, T, Meijers, T, P Van Melle, J, M Deursen, V, J Crijns, H, C Bekkers, S, C Cheriex, E, Gilbers, M, L Kietselaer, B, Knackstedt, C, Lorusso, R, Schalla, S, A Streukens, S, Chamuleau, S, M-J, Cramer, Teske, A, T Van der Spoel, Wind, A, Lokhorst, J, Liesbek, O, H Van Heusden, Tanis, W, I Van der Bilt, Vriend, J, H De Lange-van Bruggen, Karijodikoro, E, Riezebos, R, E van Dongen, Schoep, J, Stolk, V, T Offstad, J, O Beitnes, J, Helle-Valle, T, Skulstad, H, Skardal, R, Qamar, N, Furnaz, S, Ahmed, B, H Butt, M, F Khanzada, M, Saghir, T, Wahid, A, Hryniewiecki, T, Szymanski, P, Marzec, K, Misztal-Ogonowska, M, Kosmala, W, Przewlocka-Kosmala, M, Rojek, A, Woznicka, K, Zachwyc, J, Lisowska, A, Kaminska, M, D Kasprzak, J, Kowalczyk, E, F Strzecka, D, Wejner-Mik, P, Trabulo, M, Freitas, P, Ranchordas, S, Rodrigues, G, Pinto, P, Queiros, C, Azevedo, J, Marques, L, Seabra, D, Branco, L, Cruz, M, Galrinho, A, Moreira, R, Rio, P, T Timoteo, A, Selas, M, Carmelo, V, B Duque Neves, Pereira, H, Guerra, A, Marques, A, Pintassilgo, I, C Tomescu, M, N-M, Trofenciuc, Andor, M, Bordejevic, A, S Branea, H, Caruntu, F, A Velcean, L, Mavrea, A, F Onel, M, Parvanescu, T, Pop, D, L Pop-Moldovan, A, I Puticiu, M, Cirin, L, M Citu, I, A Cotoraci, C, Darabantiu, D, Farcas, R, Marincu, I, Ionac, A, Cozma, D, Mornos, C, Goanta, F, Popescu, I, Beyer, R, Mada, R, Rancea, R, Tomoaia, R, Rosianu, H, Stanescu, C, Kobalava, Z, Karaulova, J, Kotova, E, Milto, A, Pisaryuk, A, Povalyaev, N, Sorokina, M, Alrahimi, J, Elshiekh, A, Jamiel, A, Ahmed, A, Attia, N, Putnikovic, B, Dimic, A, Ivanovic, B, Matic, S, Trifunovic, D, Petrovic, J, Kosevic, D, Stojanovic, I, Petrovic, I, Dabic, P, Milojevic, P, Srdanovic, I, Susak, S, Velicki, L, Vulin, A, Kovacevic, M, Redzek, A, Stefanovic, M, C Yeo, T, W K, F Kong, K Poh, K, Vilacosta, I, Ferrera, C, Olmos, C, M Abd El Nasser, F Calvo Iglesias, Blanco-Gonzalez, E, M Bravo Amaro, Lopez-Rodriguez, E, J Lugo Adan, N Germinas, A, Pazos-Lopez, P, M Pereira Loureiro, T Perez, M, Raposeiras-Roubin, S, S Rasheed Yas, M-M, Suarez-Varela, F Vasallo Vidal, Garcia-Dorado, D, Fernandez-Hidalgo, N, Gonzalez-Alujas, T, Lozano, J, Maisterra, O, Pizzi, N, Rios, R, Bayes-Genis, A, L Pedro Botet, Vallejo, N, Llibre, C, Mateu, L, Nunez, R, Quesada, D, Berastegui, E, D Bosch Portell, J Aboal Vinas, X Albert Bertran, R Brugada Tarradellas, P Loma-Osorio Ricon, C Tiron de Llano, A Arnau, M, Bel, A, Blanes, M, Osa, A, Anguita, M, Carrasco, F, C Castillo, J, L Zamorano, J, L Moya Mur, J, Alvaro, M, Fernandez-Golfin, C, M Monteagudo, J, E Navas Elorza, C Farinas Alvarez, M, J Aguero Balbin, Zarauza, J, F Gutierrez-Diez, J, Arminanzas, C, F Arnaiz de Las Revillas, A Arnaiz Garcia, M Cobo Belaustegui, M Fernandez Sampedro, M Gutierrez Cuadra, L Garcia Cuello, C Gonzalez Rico, Rodriguez-Alvarez, R, Goikoetxea, J, Montejo, M, M Miro, J, Almela, M, Ambrosioni, J, Moreno, A, Quintana, E, Sandoval, E, Tellez, A, M Tolosana, J, Vidal, B, Falces, C, Fuster, D, Garcia-de-la-Maria, C, Hernandez-Meneses, M, Llopis, J, Marco, F, Ruiz-Zamora, I, A Bardaji Ruiz, E Sanz Girgas, Garcia-Pardo, G, M Guillen Marzo, A Rodriguez Oviedo, A Villares Jimenez, Abid, L, Hammami, R, Kammoun, S, S Mourali, M, F Mghaieth Zghal, M Ben Hlima, Boudiche, S, Ouali, S, Zakhama, L, Antit, S, Slama, I, Gulel, O, Sahin, M, Karacaglar, E, Kucukoglu, S, Cetinarslan, O, S Yasar, U, Canpolat, U, Mutlu, B, Atas, H, Dervishova, R, Ileri, C, Alhashmi, J, Tahir, J, Zarger, P, Baslib, F, Woldman, S, Menezes, L, Primus, C, Uppal, R, Bvekerwa, I, Chandrasekaran, B, Kopanska, A, Chambers, J, Hancock, J, Klein, J, Rajani, R, P Ursi, M, Cannata, S, Dworakowski, R, Fife, A, Breeze, J, Browne-Morgan, M, Gunning, M, Streather, S, M Asch, F, Zemedkun, M, Alyavi, B, Uzokov, J

Publikováno v: European Heart Journal. Quality of Care and Clinical Outcomes
European Heart Journal. Quality of Care and Clinical Outcomes, 2022, 9 (1), pp.85-96. ⟨10.1093/ehjqcco/qcac012⟩

Aims Infective endocarditis (IE) is a life-threatening disease associated with high mortality and morbidity worldwide. We sought to determine how socioeconomic factors might influence its epidemiology, clinical presentation, investigation and managem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b6d944f0573e11414f141f8ddce8da3
https://amu.hal.science/hal-03663789

The ESC-EORP EURO-ENDO (European Infective Endocarditis) registry

Autor: Habib G., Lancellotti P., Erba P. -A., Sadeghpour A., Meshaal M., Sambola A., Furnaz S., Citro R., Ternacle J., Donal E., Cosyns B., Popescu B., Iung B., Prendergast B., Laroche C., Tornos P., Pazdernik M., Maggioni A., Gale C. P., Ali Tatar-Chentir N. N., Al-Mallah M., Astrom Aneq M., Athanassopoulos G., Badano L, Benyoussef S., Calderon Aranda E., Cardim N. M., Chan K. -L., Cruz I., Edvardsen T., Goliasch G., Hagendorff A., Hristova K., Kamp O., Kang D. -H., Kong W., Matskeplishvili S., Mirocevic M., Neskovic A. N., Plonska-Gosciniak E., Popescu B. A., Raissouni M., Ronderos R., Sade L. E., Sengupta S., Separovic-Hanzevacki J., Takeuchi M., Tucay E., Tude Rodrigues A. C., Varga A., Vaskelyte J., Yamagata K., Yiangou K., Zaky H., Granada I., Mahia M., Ressi S., Nacinovich F., Iribarren A., Fernandez Oses P., Avegliano G., Filipini E., Obregon R., Bangher M., Dho J., Cartasegna L., Plastino M. L., Novas V., Shigel C., Reyes G., De Santos M., Gastaldello N., Granillo Fernandez M., Potito M., Streitenberger G., Velazco P., Casabe J. H., Cortes C., Guevara E., Salmo F., Seijo M., Weidinger F., Heger M., Brooks R., Stollberger C., Ho C. -Y., Perschy L., Puskas L., Binder C., Rosenhek R., Schneider M., Winter M. -P., Hoffer E., Melissopoulou M., Lecoq E., Legrand D., Jacquet S., Massoz M., Pierard L., Marchetta S., Dulgheru R., Emal C. D., Oury C., Droogmans S., Kerkhove D., Plein D., Soens L., Weytjens C., Motoc A., Roosens B., Lemoine I., Rodrigus I., Paelinck B., Amsel B., Unger P., Konopnicki D., Beauloye C., Pasquet A., Vanoverschelde J. L., Pierard S., Vancraeynest D., Sinnaeve F., Andrade J. L., Staszko K., Dos Santos Monteiro R., Miglioranza M. H., Shuha D. L., Alcantara M., Cravo V., Fazzio L., Felix A., Iso M., Musa C., Siciliano A. P., Villaca Filho F., Rodrigues A., Vilela F., Braga J., Silva R., Rodrigues D., Silva L., Morhy S., Fischer C., Vieira M., Afonso T., Abreu J., Falcao S. N., Moises V. A., Gouvea A., Mancuso F. J., Souza A. C., Silva C. Y., Joao G., Abboud C. S., Bellio De Mattos Barretto R., Ramos A., Arnoni R., Assef J. E., Della Togna D. J., Bihan D. L., Miglioli L., Romero Oliveira A. P., Tadeu Magro Kroll R., Cortez D., Gelape C. L., Peirira Nunes M. D. C., De Abreu Ferrari T. C., Hay K., Le V., Page M., Poulin F., Sauve C., Serri K., Mercure C., Beaudoin J., Pibarot P., Sebag I. A., Rudski L. G., Ricafort G., Barsic B., Krajinovic V., Vargovic M., Lovric D., Reskovic-Luksic V., Vincelj J., Jaksic Jurinjak S., Yiannikourides V., Ioannides M., Pofaides C., Masoura V., Pudich J., Linhart A., Siranec M., Marek J., Blechova K., Kamenik M., Pelouch R., Coufal Z., Mikulica M., Griva M., Jancova E., Mikulcova M., Taborsky M., Precek J., Jecmenova M., Latal J., Widimsky J., Butta T., MacHacek S., Vancata R., Spinar J., Holicka M., Pow Chon Long F., Anzules N., Bajana Carpio A., Largacha G., Penaherrera E., Moreira D., Mahfouz E., Elsafty E., Soliman A., Zayed Y., Aboulenein J., Abdel-Hay M., Almaghraby A., Abdelnaby M., Ahmed M., Hammad B., Saleh Y., Zahran H., Elgebaly O., Saad A., Ali M., Zeid A., El Sharkawy R., Al Kholy A., Doss R., Osama D., Rizk H., Elmogy A., Mishriky M., Assayag P., El Hatimi S., Hubert S., Casalta J. -P., Gouriet F., Arregle F., Cammilleri S., Tessonnier L., Riberi A., Botelho-Nevers E., Gagneux-Brunon A., Pierrard R., Tulane C., Campisi S., Fuzellier J. -F., Detoc M., Mehalla T., Boutoille D., Lecompte A. S., Lefebvre M., Pattier S., Al Habash O., Asseray-Madani N., Biron C., Brochard J., Caillon J., Cueff C., Tourneau T. L., Lecomte R., Magali Michel M. M., Orain J., Delarue S., Bras M. L., Faucher J. -F., Aboyans V., Beeharry A., Durox H., Lacoste M., Magne J., Mohty D., David A., Pradel V., Sierra V., Neykova A., Bettayeb B., Elkentaoui S., Tzvetkov B., Landry G., Strady C., Ainine K., Baumard S., Brasselet C., Tassigny C., Valente-Pires V., Lefranc M., Hoen B., Lefevre B., Curlier E., Callier C., Fourcade N., Jobic Y., Ansard S., Berre R. L., Ven F. L., Pouliquen M. -C., Prat G., Roux P. L., Bouchart F., Savoure A., Alarcon C., Chapuzet C., Gueit I., Tribouilloy C., Bohbot Y., Peugnet F., Gun M., Duval X., Lescure X., Ilic-Habensus E., Sadoul N., Selton-Suty C., Alla F., Goehringer F., Huttin O., Chevalier E., Garcia R., Marcis V. L., Tattevin P., Flecher E., Revest M., Chirouze C., Bouiller K., Hustache-Mathieu L., Klopfenstein T., Moreau J., Fournier D., Brunel A. -S., Lim P., Oliver L., Moussafeur A., Chavanet P., Piroth L., Salmon-Rousseau A., Buisson M., Mahy S., Martins C., Gohier S., Axler O., Baumann F., Lebras S., Piper C., Guckel D., Borgermann J., Horstkotte D., Winkelmann E., Brockmeier B., Grey D., Nickenig G., Schueler R., Ozturk C., Stohr E., Hamm C., Walther T., Brandt R., Fruhauf A. -C., Hartung C. T., Hellner C., Wild C., Becker M., Hamada S., Kaestner W., Stangl K., Knebel F., Baldenhofer G., Brecht A., Dreger H., Isner C., Pfafflin F., Stegemann M., Zahn R., Fraiture B., Kilkowski C., Karcher A. -K., Klinger S., Tolksdorf H., Tousoulis D., Aggeli C., Sideris S., Venieri E., Sarri G., Tsiapras D., Armenis I., Koutsiari A., Floros G., Grassos C., Dragasis S., Rallidis L., Varlamos C., Michalis L., Naka K., Bechlioulis A., Kotsia A., Lakkas L., Pappas K., Papadopoulos C., Kiokas S., Lioni A., Misailidou S., Barbetseas J., Bonou M., Kapelios C., Tomprou I., Zerva K., Manolis A., Hamodraka E., Athanasiou D., Haralambidis G., Samaras H., Poulimenos L., Nagy A., Bartykowszki A., Gara E., Mungulmare K., Kasliwal R., Bansal M., Ranjan S., Bhan A., Kyavar M., Maleki M., Noohi Bezanjani F., Alizadehasl A., Boudagh S., Ghavidel A., Moradnejad P., Pasha H. R., Ghadrdoost B., Gilon D., Strahilevitz J., Wanounou M., Israel S., D'Agostino C., Colonna P., Michele L. D., Fumarola F., Stante M., Marchionni N., Scheggi V., Alterini B., Del Pace S., Stefano P., Sparano C., Ruozi N., Tenaglia R., Muraru D., Limbruno U., Cresti A., Baratta P., Solari M., Giannattasio C., Moreo A., Chiara B. D., Lopez Montero B., Musca F., Orcese C. A., Panzeri F., Spano F., Russo C. F., Alfieri O., Bonis M. D., Chiappetta S., Del Forno B., Ripa M., Scarpellini P., Tassan Din C., Castiglioni B., Pasciuta R., Carletti S., Ferrara D., Guffanti M., Iaci G., Lapenna E., Nisi T., Oltolini C., Busnardo E., Pajoro U., Agricola E., Meneghin R., Schiavi D., Piscione F., Benvenga R. M., Greco L., Soriente L., Radano I., Prota C., Bellino M., Vece D. D., Santini F., Salsano A., Olivieri G. M., Turrini F., Messora R., Tondi S., Olaru A., Agnoletto V., Grassi L., Leonardi C., Sansoni S., Del Ponte S., Actis Dato G. M., Martino A. D., Ohte N., Kikuchi S., Wakami K., Aonuma K., Seo Y., Ishizu T., MacHino-Ohtsuka T., Yamamoto M., Iida N., Nakajima H., Nakagawa Y., Izumi C., Amano M., Miyake M., Takahashi K., Shiojima I., Miyasaka Y., Maeba H., Suwa Y., Taniguchi N., Tsujimoto S., Kitai T., Ota M., Yuda S., Sasaki S., Hagiwara N., Yamazaki K., Ashihara K., Arai K., Saitou C., Saitou S., Suzuki G., Shibata Y., Watanabe N., Nishino S., Ashikaga K., Kuriyama N., Mahara K., Okubo T., Fujimaki H., Shitan H., Yamamoto H., Abe K., Terada M., Takanashi S., Sata M., Yamada H., Kusunose K., Saijo Y., Seno H., Yuichiro O., Onishi T., Sera F., Nakatani S., Mizuno H., Sengoku K., Park S. W., Eun Kyoung K., Ga Yeon L., Hwang J. -W., Jin-Oh C., Park S. -J., Sang-Chol L., Sung-A C., Jang S. Y., Heo R., Lee S., Song J. -M., Jung E., Plisiene J., Dambrauskaite A., Gruodyte G., Jonkaitiene R., Mizariene V., Atkocaityte J., Zvirblyte R., Sow R., Codreanu A., Staub T., Michaux C., De La Vega E. C. L., Jacobs-Orazi L., Mallia Azzopardi C., Xuereb R. G., Piscopo T., Farrugia J., Fenech M., Pllaha E., Vella C., Borg D., Casha R., Grib L., Raevschi E., Grejdieru A., Kravcenco D., Prisacari E., Samohvalov E., Samohvalov S., Sceglova N., Panfile E., Cardaniuc L., Corcea V., Feodorovici A., Gaina V., Girbu L., Jimbei P., Balan G., Cardaniuc I., Benesco I., Marian V., Sumarga N., Bozovic B., Bulatovic N., Lakovic P., Music L., Budde R., Wahadat A., Gamela T., Meijers T., Van Melle J. P., Deursen V. M., Crijns H. J., Bekkers S. C., Cheriex E. C., Gilbers M., Kietselaer B. L., Knackstedt C., Lorusso R., Schalla S., Streukens S. A., Chamuleau S., Cramer M. -J., Teske A., Van Der Spoel T., Wind A., Lokhorst J., Liesbek O., Van Heusden H., Tanis W., Van Der Bilt I., Vriend J., Lange-Van Bruggen H. D., Karijodikoro E., Riezebos R., Van Dongen E., Schoep J., Stolk V., Offstad J. T., Beitnes J. O., Helle-Valle T., Skulstad H., Skardal R., Qamar N., Ahmed B., Butt M. H., Khanzada M. F., Saghir T., Wahid A., Hryniewiecki T., Szymanski P., Marzec K., Misztal-Ogonowska M., Kosmala W., Przewlocka-Kosmala M., Rojek A., Woznicka K., Zachwyc J., Lisowska A., Kaminska M., Kasprzak J. D., Kowalczyk E., Strzecka D. F., Wejner-Mik P., Trabulo M., Freitas P., Ranchordas S., Rodrigues G., Pinto P., Queiros C., Azevedo J., Marques L., Seabra D., Branco L., Cruz M., Galrinho A., Moreira R., Rio P., Timoteo A. T., Selas M., Carmelo V., Duque Neves B., Pereira H., Guerra A., Marques A., Pintassilgo I., Tomescu M. C., Trofenciuc N. -M., Andor M., Bordejevic A., Branea H. S., Caruntu F., Velcean L. A., Mavrea A., Onel M. F., Parvanescu T., Pop D., Pop-Moldovan A. L., Puticiu M. I., Cirin L., Citu I. M., Cotoraci C. A., Darabantiu D., Farcas R., Marincu I., Ionac A., Cozma D., Mornos C., Goanta F., Popescu I., Beyer R., Mada R., Rancea R., Tomoaia R., Rosianu H., Stanescu C., Kobalava Z., Karaulova J., Kotova E., Milto A., Pisaryuk A., Povalyaev N., Sorokina M., Alrahimi J., Elshiekh A., Jamiel A., Ahmed A., Attia N., Putnikovic B., Dimic A., Ivanovic B., Matic S., Trifunovic D., Petrovic J., Kosevic D., Stojanovic I., Petrovic I., Dabic P., Milojevic P., Srdanovic I., Susak S., Velicki L., Vulin A., Kovacevic M., Redzek A., Stefanovic M., Yeo T. C., Kong W. K. F., Poh K. K., Vilacosta I., Ferrera C., Olmos C., Abd El-Nasser M., Calvo Iglesias F., Blanco-Gonzalez E., Bravo Amaro M., Lopez-Rodriguez E., Lugo Adan J., Germinas A. N., Pazos-Lopez P., Pereira Loureiro M., Perez M. T., Raposeiras-Roubin S., Rasheed Yas S., Suarez-Varela M. -M., Vasallo Vidal F., Garcia-Dorado D., Fernandez-Hidalgo N., Gonzalez-Alujas T., Lozano J., Maisterra O., Pizzi N., Rios R., Bayes-Genis A., Pedro Botet L., Vallejo N., Llibre C., Mateu L., Nunez R., Quesada D., Berastegui E., Bosch Portell D., Aboal Vinas J., Albert Bertran X., Brugada Tarradellas R., Loma-Osorio Ricon P., Tiron De Llano C., Arnau M. A., Bel A., Blanes M., Osa A., Anguita M., Carrasco F., Castillo J. C., Zamorano J. L., Moya Mur J. L., Alvaro M., Fernandez-Golfin C., Monteagudo J. M., Navas Elorza E., Farinas Alvarez M. C., Aguero Balbin J., Zarauza J., Gutierrez-Diez J. F., Arminanzas C., Arnaiz De Las Revillas F., Arnaiz Garcia A., Cobo Belaustegui M., Fernandez Sampedro M., Gutierrez Cuadra M., Garcia Cuello L., Gonzalez Rico C., Rodriguez-Alvarez R., Goikoetxea J., Montejo M., Miro J. M., Almela M., Ambrosioni J., Moreno A., Quintana E., Sandoval E., Tellez A., Tolosana J. M., Vidal B., Falces C., Fuster D., Garcia-De-La-Maria C., Hernandez-Meneses M., Llopis J., Marco F., Ruiz-Zamora I., Bardaji Ruiz A., Sanz Girgas E., Garcia-Pardo G., Guillen Marzo M., Rodriguez Oviedo A., Villares Jimenez A., Abid L., Hammami R., Kammoun S., Mourali M. S., Ben Hlima M., Boudiche S., Ouali S., Zakhama L., Antit S., Slama I., Gulel O., Sahin M., Karacaglar E., Kucukoglu S., Cetinarslan O., Yasar U. S., Canpolat U., Mutlu B., Atas H., Dervishova R., Ileri C., Alhashmi J., Tahir J., Zarger P., Baslib F., Woldman S., Menezes L., Primus C., Uppal R., Bvekerwa I., Chandrasekaran B., Kopanska A., Chambers J., Hancock J., Klein J., Rajani R., Ursi M. P., Cannata S., Dworakowski R., Fife A., Breeze J., Browne-Morgan M., Gunning M., Streather S., Asch F. M., Zemedkun M., Alyavi B., Uzokov J.

Publikováno v: European heart journal-Quality of care and clinical outcomes, 5(3), 202-207. Oxford University Press
European Heart Journal-Quality of Care and Clinical Outcomes, Volume 5, Issue 3, July 2019, Pages 202-207
European heart journal. Quality of care & clinical outcomes, Vol. 5, no. 3, p. 202-207 (2019)
European Heart Journal. Quality of Care and Clinical Outcomes
European Heart Journal. Quality of Care and Clinical Outcomes, 2019, 5 (3), pp.202-207. ⟨10.1093/ehjqcco/qcz018⟩
European heart journal-Quality of care & clinical outcomes, 5(3), 202-207. Oxford University Press
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
European Heart Journal-Quality of Care and Clinical Outcomes, 5(3), 202

Aims The European Society of Cardiology (ESC) EURObservational Research Programme (EORP) European Endocarditis (EURO-ENDO) registry aims to study the care and outcomes of patients diagnosed with infective endocarditis (IE) and compare findings with r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::481f3db9a4f065bb9aa0ed4f025a068f
https://doi.org/10.1093/ehjqcco/qcz018

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Jan Hoving, Frederiksoord

Autor: Stolk, V. J., Gasenbeek, B.

Publikováno v: Vrijdenken & humanisme in Nederland. 40 plekken van herinnering

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::cd366d75ced168b19bfbf5c9932f8682
https://research.uvh.nl/en/publications/45ee94da-05d8-456a-9608-01cd1d4b425e