An LQT2-related mutation in the voltage-sensing domain is involved in switching the gating polarity of hERG.

Autor: Liu, Zhipei^1,2 (AUTHOR), Wang, Feng^1,3 (AUTHOR), Yuan, Hui^1,3 (AUTHOR), Tian, Fuyun^1,2 (AUTHOR), Yang, Chuanyan^1,2,4 (AUTHOR), Hu, Fei^1,2 (AUTHOR), Liu, Yiyao¹ (AUTHOR), Tang, Meiqin^1,5 (AUTHOR), Ping, Meixuan^1,2,6 (AUTHOR), Kang, Chunlan^1,5 (AUTHOR), Luo, Ting^1,7 (AUTHOR), Yang, Guimei^1,3 (AUTHOR), Hu, Mei^1,8 (AUTHOR), Gao, Zhaobing^1,2,3,6 (AUTHOR) zbgao@simm.ac.cn, Li, Ping^1,2,3,6 (AUTHOR) lipingt@simm.ac.cn

Publikováno v: BMC Biology. 2/5/2024, Vol. 22 Issue 1, p1-14. 14p.

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A previously unrecognized superfamily of macro-conotoxins includes an inhibitor of the sensory neuron calcium channel Cav2.3.

Autor: Hackney, Celeste M.¹ (AUTHOR), Flórez Salcedo, Paula² (AUTHOR), Mueller, Emilie³ (AUTHOR), Koch, Thomas Lund^4,5 (AUTHOR), Kjelgaard, Lau D.¹ (AUTHOR), Watkins, Maren⁶ (AUTHOR), Zachariassen, Linda⁷ (AUTHOR), Tuelund, Pernille Sønderby⁷ (AUTHOR), McArthur, Jeffrey R.⁸ (AUTHOR), Adams, David J.⁸ (AUTHOR), Kristensen, Anders S.⁷ (AUTHOR), Olivera, Baldomero⁶ (AUTHOR), Finol-Urdaneta, Rocio K.^8,9 (AUTHOR), Safavi-Hemami, Helena^4,5,6 (AUTHOR), Morth, Jens Preben³ (AUTHOR), Ellgaard, Lars¹ (AUTHOR) lellgaard@bio.ku.dk

Publikováno v: PLoS Biology. 8/3/2023, Vol. 21 Issue 8, p1-32. 32p. 5 Diagrams, 1 Chart, 2 Graphs.

Human neutrophils contain a protein kinase C-like enzyme that utilizes guanosine triphosphate as a phosphate donor. Cofactor requirements, kinetics, and endogenous acceptor proteins

Autor: Stoehr, SJ, Smolen, JE

Publikováno v: Blood; January 1990, Vol. 75 Issue: 2 p479-487, 9p