MLX phosphorylation stabilizes the ChREBP-MLX heterotetramer on tandem E-boxes to control carbohydrate and lipid metabolism.

Autor: Cadena Del Castillo CE; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium., Deniz O; Institute of Biotechnology, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland., van Geest F; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium., Rosseels L; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium., Stockmans I; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium., Robciuc M; Institute of Biotechnology, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland., Carpentier S; Facility for Systems Biology Based Mass Spectrometry, KU Leuven, Leuven, Belgium., Wölnerhanssen BK; St. Clara Research Ltd, St. Claraspital, Basel, Switzerland.; University of Basel, Basel, Switzerland., Meyer-Gerspach AC; St. Clara Research Ltd, St. Claraspital, Basel, Switzerland.; University of Basel, Basel, Switzerland., Peterli R; Clarunis, University Digestive Health Care Center, St. Clara Hospital and University Hospital Basel, Switzerland., Hietakangas V; Institute of Biotechnology, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland., Shimobayashi M; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Sep 05. Date of Electronic Publication: 2024 Sep 05.

The serine synthesis pathway drives osteoclast differentiation through epigenetic regulation of NFATc1 expression.

Autor: Stegen S; Laboratory of Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium., Moermans K; Laboratory of Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium., Stockmans I; Laboratory of Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium., Thienpont B; Laboratory of Functional Epigenetics, Department of Human Genetics, KU Leuven, Leuven, Belgium., Carmeliet G; Laboratory of Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium. geert.carmeliet@kuleuven.be.

Publikováno v: Nature metabolism [Nat Metab] 2024 Jan; Vol. 6 (1), pp. 141-152. Date of Electronic Publication: 2024 Jan 10.

Trpv6 mediates intestinal calcium absorption during calcium restriction and contributes to bone homeostasis

Autor: Lieben, L., Benn, B.S., Ajibade, D., Stockmans, I., Moermans, K., Hediger, M.A., Peng, J.B., Christakos, S., Bouillon, R., Carmeliet, G.

Publikováno v: In Bone 2010 47(2):301-308

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De novo serine synthesis regulates chondrocyte proliferation during bone development and repair.

Autor: Stegen S; Laboratory of Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, 3000, Leuven, Belgium., Loopmans S; Laboratory of Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, 3000, Leuven, Belgium., Stockmans I; Laboratory of Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, 3000, Leuven, Belgium., Moermans K; Laboratory of Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, 3000, Leuven, Belgium., Carmeliet P; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology, 3000, Leuven, Belgium.; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute, KU Leuven, 3000, Leuven, Belgium.; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, 510080, China., Carmeliet G; Laboratory of Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, 3000, Leuven, Belgium. geert.carmeliet@kuleuven.be.

Publikováno v: Bone research [Bone Res] 2022 Feb 15; Vol. 10 (1), pp. 14. Date of Electronic Publication: 2022 Feb 15.