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pro vyhledávání: '"Stine Timmermann"'
Publikováno v:
Clinical Pharmacology in Drug Development. 11:910-921
Tralokinumab is the first biologic therapy for moderate-to-severe atopic dermatitis (AD) that specifically neutralizes interleukin-13 activity, a key driver of AD signs and symptoms. Tralokinumab is a human immunoglobulin G4 monoclonal antibody admin
Autor:
Anders Hall, Stine Timmermann
Publikováno v:
Basic & Clinical Pharmacology & Toxicology
Brodalumab is a fully human monoclonal antibody targeting the IL‐17 receptor A leading to an inhibition of the biological effect of IL‐17A, IL‐17F, IL‐17A/F heterodimer, IL‐17C and IL‐17E isoforms. It has shown to be efficacious in the tr
Autor:
Claus Tornby Christoffersen, John Paul Kilburn, Benny Bang-Andersen, Christoffer Bundgaard, Søren Rahn Christensen, Alf Thibblin, Stine Timmermann, Mads Kreilgaard, Jan Kehler, Bjoern Steiniger-Brach, Gunnar Antoni, Jacob Nielsen, Mark Lubberink, Lise T. Brennum, Sergio Estrada, Anders Wall
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 55(9)
Phosphodiesterase 10A (PDE10A) plays a key role in the regulation of brain striatal signaling, and several pharmaceutical companies currently investigate PDE10A inhibitors in clinical trials for various central nervous system diseases. A PDE10A PET l
Publikováno v:
Mathematical biosciences. 257
In the Western world approximately 10% of the population experience severe depression at least once in their lifetime and many more experience a mild form of depression. Depression has been associated with malfunctions in the hypothalamus-pituitary-a
Autor:
Stine Timmermann, Johnny T. Ottesen
Publikováno v:
Physics of Fluids. 21:053601
This study investigates the occurrence of valveless pumping in a fluid-filled system consisting of two open tanks connected by an elastic tube. We show that directional flow can be achieved by introducing a periodic pinching applied at an asymmetrica