Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Stine Smedegaard"'
Publikováno v:
The Journal of Biological Chemistry
Guérillon, C, Smedegaard, S, Hendriks, I A, Nielsen, M L & Mailand, N 2020, ' Multisite SUMOylation restrains DNA polymerase η interactions with DNA damage sites ', Journal of Biological Chemistry, vol. 295, pp. 8350-8362 . https://doi.org/10.1074/jbc.RA120.013780
Guérillon, C, Smedegaard, S, Hendriks, I A, Nielsen, M L & Mailand, N 2020, ' Multisite SUMOylation restrains DNA polymerase η interactions with DNA damage sites ', Journal of Biological Chemistry, vol. 295, pp. 8350-8362 . https://doi.org/10.1074/jbc.RA120.013780
Translesion DNA synthesis (TLS) mediated by low-fidelity DNA polymerases is an essential cellular mechanism for bypassing DNA lesions that obstruct DNA replication progression. However, the access of TLS polymerases to the replication machinery must
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af1c3ead8c9b910ab1ecefb9e87b983
https://pubmed.ncbi.nlm.nih.gov/32350109
https://pubmed.ncbi.nlm.nih.gov/32350109
Autor:
Chunaram Choudhary, Petra Beli, Sofie V. Nielsen, Tina Thorslund, Niels Mailand, Anna Mosbech, Konstantinos Kagias, Garry G Sedgwick, Simon Bekker-Jensen, Claudia Lukas, Ian Gibbs-Seymour, Jiri Lukas, Stine Smedegaard, Lou Klitgaard Povlsen, Roger Pocock, Rasmus Hartmann-Petersen
Publikováno v:
Nature Structural & Molecular Biology. 19:1084-1092
Ubiquitin-mediated processes orchestrate critical DNA-damage signaling and repair pathways. We identify human DVC1 (C1orf124; Spartan) as a cell cycle-regulated anaphase-promoting complex (APC) substrate that accumulates at stalled replication forks.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4119c519a36939e9005441019bc67d41
https://doi.org/10.1038/nsmb.2395
https://doi.org/10.1038/nsmb.2395
Autor:
Tine K. Nielsen, Charlotte Svensson, Diego Iglesias-Gato, Amilcar Flores-Morales, Giuseppe Cazzamali, Christina Aaen Andresen, Stine Smedegaard, Michael L. Nielsen, Kathrine B. Sylvestersen
Publikováno v:
The Journal of biological chemistry. 289(4)
The ankyrin and SOCS (suppressor of cytokine signaling) box (ASB) family of proteins function as the substrate recognition subunit in a subset of Elongin-Cullin-SOCS (ECS) E3 ubiquitin ligases. Despite counting 18 members in humans, the identity of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0d8c49b3d9fe8bfbff9c7fcbac7f378
https://pubmed.ncbi.nlm.nih.gov/24337577
https://pubmed.ncbi.nlm.nih.gov/24337577
Autor:
Matthias Mann, Francisco J. Blanco, Yasuyoshi Oka, Anja Groth, Kyosuke Nakamura, Niels Mailand, Gulnahar B. Mortuza, Simon Bekker-Jensen, Guillermo Montoya, Markus Räschle, Stine Smedegaard, Saskia Hoffmann, Yunpeng Feng, Alain Ibáñez de Opakua
Publikováno v:
Hoffmann, S, Smedegaard, S, Nakamura, K, Mortuza, G B, Räschle, M, Ibañez de Opakua, A, Oka, Y, Feng, Y, Blanco, F J, Mann, M, Montoya, G, Groth, A, Bekker-Jensen, S & Mailand, N 2016, ' TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress ', The Journal of Cell Biology, vol. 212, no. 1, pp. 63-75 . https://doi.org/10.1083/jcb.201506071
The Journal of Cell Biology
The Journal of Cell Biology
The E3 ubiquitin ligase TRAIP associates with replication forks through direct interaction with PCNA, promoting checkpoint signaling and genome stability after replication stress.
Cellular genomes are highly vulnerable to perturbations to chromo
Cellular genomes are highly vulnerable to perturbations to chromo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4e1f25086c99d554f4f08d27269a1bb
https://doi.org/10.1084/jem.2131oia127
https://doi.org/10.1084/jem.2131oia127