Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Stine Mencl"'
Autor:
Steffen Haupeltshofer, Stine Mencl, Rebecca D. Szepanowski, Christina Hansmann, Ana I. Casas, Hanna Abberger, Wiebke Hansen, Alina Blusch, Cornelius Deuschl, Michael Forsting, Dirk M. Hermann, Friederike Langhauser, Christoph Kleinschnitz
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-12 (2024)
Abstract Activation of the kallikrein-kinin system promotes vascular leakage, inflammation, and neurodegeneration in ischemic stroke. Inhibition of plasma kallikrein (PK) – a key component of the KKS – in the acute phase of ischemic stroke has be
Externí odkaz:
https://doaj.org/article/47314db5edc8456c8ff87473e47850e1
Autor:
Christina David, Tobias Ruck, Leoni Rolfes, Stine Mencl, Peter Kraft, Michael K. Schuhmann, Christina B. Schroeter, Robin Jansen, Friederike Langhauser, Anne K. Mausberg, Anke C. Fender, Sven G. Meuth, Christoph Kleinschnitz
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 12 (2023)
Background Typically defined as a thromboinflammatory disease, ischemic stroke features early and delayed inflammatory responses, which determine the extent of ischemia‐related brain damage. T and natural killer cells have been implicated in neuron
Externí odkaz:
https://doaj.org/article/47877b69926b4bd58690f27262adb83a
Autor:
Anne-Katrin Rohlfing, Kyra Kolb, Manuel Sigle, Melanie Ziegler, Alexander Bild, Patrick Münzer, Jessica Sudmann, Valerie Dicenta, Tobias Harm, Mailin-Christin Manke, Sascha Geue, Marcel Kremser, Madhumita Chatterjee, Chunguang Liang, Hendrik von Eysmondt, Thomas Dandekar, David Heinzmann, Manina Günter, Saskia von Ungern-Sternberg, Manuela Büttcher, Tatsiana Castor, Stine Mencl, Friederike Langhauser, Katharina Sies, Diyaa Ashour, Mustafa Caglar Beker, Michael Lämmerhofer, Stella E. Autenrieth, Tilman E. Schäffer, Stefan Laufer, Paulina Szklanna, Patricia Maguire, Matthias Heikenwalder, Karin Anne Lydia Müller, Dirk M. Hermann, Ertugrul Kilic, Ralf Stumm, Gustavo Ramos, Christoph Kleinschnitz, Oliver Borst, Harald F. Langer, Dominik Rath, Meinrad Gawaz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
ACKR3 is a critical regulator of platelet-mediated thrombosis and organ injury following ischemia/reperfusion. Platelet ACKR3 surface expression is independently associated with all-cause mortality in patients with cardiovascular diseases.
Externí odkaz:
https://doaj.org/article/bff45f142b4844968bc8a69ceae8231a
Autor:
Rebecca D. Steubing, Fabian Szepanowski, Christina David, Ayan Mohamud Yusuf, Stine Mencl, Anne-Kathrin Mausberg, Harald F. Langer, Manuela Sauter, Cornelius Deuschl, Michael Forsting, Anke C. Fender, Dirk M. Hermann, Ana I. Casas, Friederike Langhauser, Christoph Kleinschnitz
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 24, Iss , Pp 100493- (2022)
Platelets are key mediators of thrombus formation and inflammation during the acute phase of ischaemic stroke. Particularly, the platelet glycoprotein (GP) receptors GPIbα and GPVI have been shown to mediate platelet adhesion and activation in the i
Externí odkaz:
https://doaj.org/article/f73f2d595ae0433c87b3d9d337e41989
Autor:
Peter Kraft, Michael K Schuhmann, Cornelia Garz, Solveig Jandke, Daniela Urlaub, Stine Mencl, Alma Zernecke, Hans-Jochen Heinze, Roxana O Carare, Christoph Kleinschnitz, Stefanie Schreiber
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182822 (2017)
While hypercholesterolemia plays a causative role for the development of ischemic stroke in large vessels, its significance for cerebral small vessel disease (CSVD) remains unclear. We thus aimed to understand the detailed relationship between hyperc
Externí odkaz:
https://doaj.org/article/39c599d403c349eea4ca44c55cbef83e
Autor:
Jasvir Kaur, Stine Mencl, Ayse Sahaboglu, Pietro Farinelli, Theo van Veen, Eberhart Zrenner, Per Ekström, François Paquet-Durand, Blanca Arango-Gonzalez
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22181 (2011)
Retinitis pigmentosa (RP) is a heterogeneous group of inherited neurodegenerative diseases affecting photoreceptors and causing blindness. Many human cases are caused by mutations in the rhodopsin gene. An important question regarding RP pathology is
Externí odkaz:
https://doaj.org/article/6a7fafc52c05425c83e1cab711c66b13
Autor:
Mariella Schmidt, Steffen Pfeuffer, Catharina C. Gross, Michael Gliem, Christoph Kleinschnitz, Jens Minnerup, Sven G. Meuth, Jan-Kolja Strecker, Tobias Ruck, Stine Mencl, Leoni Rolfes, Christina David, Michael K. Schuhmann, Stefanie Bock, Andreas-Schulte Mecklenbeck
Rag1−/− mice, lacking functional B and T cells, have been extensively used as an adoptive transfer model to evaluate neuroinflammation in stroke research. However, it remains unknown whether natural killer (NK) cell development and functions are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::788a230e3ec0d9f11341c02ed0d965c1
https://www.ncbi.nlm.nih.gov/pubmed/34105078
https://www.ncbi.nlm.nih.gov/pubmed/34105078
Autor:
Anne-Katrin, Rohlfing, Kyra, Kolb, Manuel, Sigle, Melanie, Ziegler, Alexander, Bild, Patrick, Münzer, Jessica, Sudmann, Valerie, Dicenta, Tobias, Harm, Mailin-Christin, Manke, Sascha, Geue, Marcel, Kremser, Madhumita, Chatterjee, Chunguang, Liang, Hendrik, von Eysmondt, Thomas, Dandekar, David, Heinzmann, Manina, Günter, Saskia, von Ungern-Sternberg, Manuela, Büttcher, Tatsiana, Castor, Stine, Mencl, Friederike, Langhauser, Katharina, Sies, Diyaa, Ashour, Mustafa Caglar, Beker, Michael, Lämmerhofer, Stella E, Autenrieth, Tilman E, Schäffer, Stefan, Laufer, Paulina, Szklanna, Patricia, Maguire, Matthias, Heikenwalder, Karin Anne Lydia, Müller, Dirk M, Hermann, Ertugrul, Kilic, Ralf, Stumm, Gustavo, Ramos, Christoph, Kleinschnitz, Oliver, Borst, Harald F, Langer, Dominik, Rath, Meinrad, Gawaz
Platelet activation plays a critical role in thrombosis. Inhibition of platelet activation is a cornerstone in treatment of acute organ ischemia. Platelet ACKR3 surface expression is independently associated with all-cause mortality in CAD patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2174660c459076f47139948dc9022213
https://hdl.handle.net/20.500.12511/9351
https://hdl.handle.net/20.500.12511/9351
Autor:
Leoni, Rolfes, Tobias, Ruck, Christina, David, Stine, Mencl, Stefanie, Bock, Mariella, Schmidt, Jan-Kolja, Strecker, Steffen, Pfeuffer, Andreas-Schulte, Mecklenbeck, Catharina, Gross, Michael, Gliem, Jens, Minnerup, Michael K, Schuhmann, Christoph, Kleinschnitz, Sven G, Meuth
Publikováno v:
Translational Stroke Research
Rag1−/− mice, lacking functional B and T cells, have been extensively used as an adoptive transfer model to evaluate neuroinflammation in stroke research. However, it remains unknown whether natural killer (NK) cell development and functions are
Autor:
Valentin Hautmann, Stefanie Kuerten, Subba Rao Mekala, Tobias Koeniger, Philipp Wörsdörfer, Luisa Bell, Stine Mencl, Philipp Kirchner, Süleyman Ergün, Michael Enders, Christian Schulz, Christoph Kleinschnitz, Anika Mifka, Arif B. Ekici
Publikováno v:
Stem cells (Dayton, Ohio)REFERENCES. 39(2)
Although the bone marrow contains most hematopoietic activity during adulthood, hematopoietic stem and progenitor cells can be recovered from various extramedullary sites. Cells with hematopoietic progenitor properties have even been reported in the