Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Stine Just Maarbjerg"'
Autor:
Ramin Tehranchi, MD, PhD, MBA, Jonas Pettersson, MD, PhD, Anita E. Melgaard, MSc, Friedeborg Seitz, MD, Anders Valeur, PhD, Stine Just Maarbjerg, PhD
Publikováno v:
Current Therapeutic Research, Vol 96, Iss , Pp 100668- (2022)
ABSTRACT: Background: Dasiglucagon is a novel glucagon analog that is stable in aqueous formulation and approved for use in severe hypoglycemia. Concentration-QTc analyses are critical for assessing risk of drug-induced QTc prolongation and potential
Externí odkaz:
https://doaj.org/article/038e8122e5584c64844bb4d1b6736f0c
356-P: Population Pharmacokinetic Modeling of Dasiglucagon in Subjects with Type 1 Diabetes Mellitus
Autor:
Stine Just Maarbjerg, Paul M. Diderichsen, Han Witjes, Anders H. Valeur, Carsten Boye Knudsen, Ramin Tehranchi
Publikováno v:
Diabetes. 70
To quantify the impact of subject covariates on pharmacokinetics (PK) of the novel, ready-to-use glucagon analog dasiglucagon, we developed a population PK model. Dasiglucagon pharmacokinetics was dose linear in the tested dose range (0.1 to 1.0 mg)