Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Stine J Maarbjerg"'
Autor:
Christian Frøsig, Thomas E Jensen, Jacob Jeppesen, Christian Pehmøller, Jonas T Treebak, Stine J Maarbjerg, Jonas M Kristensen, Lykke Sylow, Thomas J Alsted, Peter Schjerling, Bente Kiens, Jørgen F P Wojtaszewski, Erik A Richter
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62338 (2013)
The 5'-AMP-activated protein kinase (AMPK) is considered "a metabolic master-switch" in skeletal muscle reducing ATP- consuming processes whilst stimulating ATP regeneration. Within recent years, AMPK has also been proposed as a potential target to a
Externí odkaz:
https://doaj.org/article/dc98e45ee71b43d38484f0835f31be3d
Autor:
Flemming L. Søndergaard, Morten Donsmark, Stine J. Maarbjerg, Astrid Breitschaft, Jeanett Borregaard, Tine A. Bækdal
Publikováno v:
Diabetes Therapy
Introduction Oral semaglutide is a novel tablet formulation of the human glucagon-like peptide-1 analogue semaglutide. In two trials, the effects of prior food ingestion (food effect), post-dose fasting period and water volume with dosing (dosing con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e594a7d392c528f09113d6340f1caa15
https://doi.org/10.1007/s13300-021-01078-y
https://doi.org/10.1007/s13300-021-01078-y
Autor:
Kim G. Madsen, Flemming L. Søndergaard, Jonas Ahnfelt-Rønne, Andrew J. Benie, Simon Bjerregaard, Jeanett Borregaard, Tine A. Bækdal, Betty Lomstein Pedersen, Susanne Schéele, Charles Pyke, Marie-Louise Hartoft-Nielsen, Stephen T. Buckley, Tomas Alanentalo, Rikke Bjerring Skyggebjerg, Rikke Kaae Kirk, Lotte Bjerre Knudsen, Stine J. Maarbjerg, Holger M. Strauss, Andreas Vegge, Csaba Fekete, Erzsébet Farkas, Per-Olof Wahlund
Publikováno v:
Science Translational Medicine. 10
Oral administration of therapeutic peptides is hindered by poor absorption across the gastrointestinal barrier and extensive degradation by proteolytic enzymes. Here, we investigated the absorption of orally delivered semaglutide, a glucagon-like pep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da23aec5d09c52d95e43b0ca9e999cdb
https://doi.org/10.1126/scitranslmed.aar7047
https://doi.org/10.1126/scitranslmed.aar7047
Autor:
Jacob Jeppesen, Annette K. Serup, David M. Thomson, Niels Jessen, Klaus Qvortrup, Roger W. Hunter, Kasper Thorsen, Andreas Børsting Jordy, Kei Sakamoto, Christian Pehmøller, Jason R.B. Dyck, Clara Prats, Lykke Sylow, Stine J. Maarbjerg, Andreas M. Fritzen, Peter Schjerling, Erik A. Richter, Bente Kiens, Jørgen F. P. Wojtaszewski
Publikováno v:
Diabetes
Jeppesen, J F, Maarbjerg, S J, Jordy, A B, Fritzen, A M, Pehmøller, C K, Hansen, L S, Serup, A K L, Jessen, N, Thorsen, K, Prats, C, Qvortrup, K, Dyck, J R B, Hunter, R W, Sakamoto, K, Thomson, D M, Schjerling, P, Wojtaszewski, J, Richter, E & Kiens, B 2013, ' LKB1 regulates lipid oxidation during exercise independently of AMPK ', Diabetes, vol. 62, no. 5, pp. 1490-9 . https://doi.org/10.2337/db12-1160
Jeppesen, J F, Maarbjerg, S J, Jordy, A B, Fritzen, A M, Pehmøller, C K, Hansen, L S, Serup, A K L, Jessen, N, Thorsen, K, Prats, C, Qvortrup, K, Dyck, J R B, Hunter, R W, Sakamoto, K, Thomson, D M, Schjerling, P, Wojtaszewski, J, Richter, E & Kiens, B 2013, ' LKB1 regulates lipid oxidation during exercise independently of AMPK ', Diabetes, vol. 62, no. 5, pp. 1490-9 . https://doi.org/10.2337/db12-1160
Lipid metabolism is important for health and insulin action, yet the fundamental process of regulating lipid metabolism during muscle contraction is incompletely understood. Here, we show that liver kinase B1 (LKB1) muscle-specific knockout (LKB1 MKO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbf21f49b331333e7662a87e83af3c8b
https://doi.org/10.2337/db12-1160
https://doi.org/10.2337/db12-1160
Autor:
Stine J. Maarbjerg, Joshua R. Mouatt, Shlomit Boguslavsky, Maximilian Kleinert, Lykke Sylow, Thomas E. Jensen, Jacob Jeppesen, Clara Prats, Erik A. Richter, Peter Schjerling, Amira Klip, Tim T. Chiu
Publikováno v:
Diabetes
In skeletal muscle, the actin cytoskeleton-regulating GTPase, Rac1, is necessary for insulin-dependent GLUT4 translocation. Muscle contraction increases glucose transport and represents an alternative signaling pathway to insulin. Whether Rac1 is act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06119391c4989f520d17c094deecf661
http://europepmc.org/articles/PMC3609592
http://europepmc.org/articles/PMC3609592
Autor:
Christian, Frøsig, Mini P, Sajan, Stine J, Maarbjerg, Nina, Brandt, Carsten, Roepstorff, Jørgen F P, Wojtaszewski, Bente, Kiens, Robert V, Farese, Erik A, Richter
Publikováno v:
The Journal of physiology. 582(Pt 3)
We investigated if acute endurance-type exercise interacts with insulin-stimulated activation of atypical protein kinase C (aPKC) and insulin signalling to peptide chain elongation in human skeletal muscle. Four hours after acute one-legged exercise,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c478b9946fa99f37dd8a6de95dcbe66d
https://pubmed.ncbi.nlm.nih.gov/17540697
https://pubmed.ncbi.nlm.nih.gov/17540697
Autor:
Thomas E. Jensen, Lykke Sylow, Adam J. Rose, Agnete B. Madsen, Yeliz Angin, Stine J. Maarbjerg, Erik A. Richter
Publikováno v:
Molecular Metabolism, Vol 3, Iss 7, Pp 742-753 (2014)
Understanding how muscle contraction orchestrates insulin-independent muscle glucose transport may enable development of hyperglycemia-treating drugs. The prevailing concept implicates Ca2+ as a key feed forward regulator of glucose transport with se
Externí odkaz:
https://doaj.org/article/054097813ac940bc997a3e8a0a423b12
Autor:
Daphna D.J. Habets, Joost J.F.P. Luiken, Margriet eOuwens, Will A. Coumans, Monique eVergouwe, Stine J. Maarbjerg, Michael eLeitges, Arend eBonen, Erik A. Richter, Jan eGlatz
Publikováno v:
Frontiers in Physiology, Vol 3 (2012)
Aim: The signaling pathways involved in the regulation of cardiac GLUT4 translocation/glucose uptake and CD36 translocation/ long-chain fatty acid uptake are not fully understood. We compared in heart/muscle-specific PKC-λ knockout mice the roles of
Externí odkaz:
https://doaj.org/article/04f8238d65434a8581d9b4b612769d9e