Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Stina Lindman"'
Autor:
Carl Diehl, Mikael C. Bauer, Sara Linse, Mikael Akke, Stina Lindman, Mikael Lund, Frans A. A. Mulder
Publikováno v:
Biophysical Journal, 99(10), 3365-3373. CELL PRESS
Understanding the role of electrostatics in protein stability requires knowledge of these interactions in both the folded and unfolded states. Electrostatic interactions can be probed experimentally by characterizing ionization equilibria of titratin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4816d6941b01ea8c21dc48b8faac58f4
https://hdl.handle.net/11370/111f4ae6-e171-4d65-82e9-fe599344da98
https://hdl.handle.net/11370/111f4ae6-e171-4d65-82e9-fe599344da98
Publikováno v:
Proceedings of the National Academy of Sciences. 107:19826-19831
Protein stabilization was achieved through in vivo screening based on the thermodynamic linkage between protein folding and fragment complementation. The split GFP system was found suitable to derive protein variants with enhanced stability due to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::328f1f2ce7bc6c7d72b0a5a17c1b50c6
https://doi.org/10.1073/pnas.1005689107
https://doi.org/10.1073/pnas.1005689107
Autor:
Cecilia Forsberg, Erika Gustafsson, Karin Barchan, Kok P. M. van Kessel, Karin Haraldsson, Anna Rosén, Christina Furebring, Pieter-Jan A. Haas, Jos A. G. van Strijp, Björn Walse, Lill Ljung, Stina Lindman, Karin Bryder
Publikováno v:
Protein Engineering, Design and Selection. 23:91-101
Chemotaxis inhibitory protein of Staphylococcus aureus (CHIPS) is a protein that binds and blocks the C5a receptor (C5aR) and formylated peptide receptor, thereby inhibiting the immune cell recruitment associated with inflammation. If CHIPS was less
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2aaf13f755a792701210d93349843a9
https://doi.org/10.1093/protein/gzp062
https://doi.org/10.1093/protein/gzp062
Publikováno v:
Protein Science. 18:1221-1229
The affinity between the 1-157 and 158-238 fragments of green fluorescent protein (GFP) is too low for spontaneous in vivo reassembly of the protein upon co-expression of the two fragments. This prevents chromophore maturation and the cells lack GFP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98caa1b2506850b4d94975623560524c
https://doi.org/10.1002/pro.131
https://doi.org/10.1002/pro.131
Autor:
Aedín M. Minogue, Eva Thulin, Kenneth A. Dawson, Fiona Quinlan-Pluck, Celia Cabaleiro-Lago, Dominic M. Walsh, Sara Linse, Stina Lindman, Iseult Lynch
Publikováno v:
Journal of the American Chemical Society. 130:15437-15443
Copolymeric NiPAM:BAM nanoparticles of varying hydrophobicity were found to retard fibrillation of the Alzheimer's disease-associated amyloid beta protein (Abeta). We found that these nanoparticles affect mainly the nucleation step of Abeta fibrillat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92be57678eb03c35a710c3367c2c0ddf
https://doi.org/10.1021/ja8041806
https://doi.org/10.1021/ja8041806
Autor:
Kenneth A. Dawson, Sara Linse, Stina Lindman, Iseult Lynch, Sheena E. Radford, Eva Thulin, Wei-Feng Xue, Celia Cabaleiro-Lago
Publikováno v:
Proceedings of the National Academy of Sciences. 104:8691-8696
Nanoparticles present enormous surface areas and are found to enhance the rate of protein fibrillation by decreasing the lag time for nucleation. Protein fibrillation is involved in many human diseases, including Alzheimer's, Creutzfeld-Jacob disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bccd7025e27444f45e6927195005b12f
https://doi.org/10.1073/pnas.0701250104
https://doi.org/10.1073/pnas.0701250104
Publikováno v:
Nano Letters. 7:914-920
Nanoparticles in biological fluids almost invariably become coated with proteins that may confer nanomedical and nanotoxicological effects. Understanding these effects requires quantitative measurements using simple systems. Adsorption of HSA to copo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2adbe19484c7904601daef5c187c2c2f
https://doi.org/10.1021/nl062743+
https://doi.org/10.1021/nl062743+
Autor:
Hanna Nilsson, Kenneth A. Dawson, Tord Berggård, Eva Thulin, Iseult Lynch, Tommy Cedervall, Sara Linse, Stina Lindman
Publikováno v:
Proceedings of the National Academy of Sciences. 104:2050-2055
Due to their small size, nanoparticles have distinct properties compared with the bulk form of the same materials. These properties are rapidly revolutionizing many areas of medicine and technology. Despite the remarkable speed of development of nano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4d0c7f3a9e1473088a534140426bf0c
https://doi.org/10.1073/pnas.0608582104
https://doi.org/10.1073/pnas.0608582104
Publikováno v:
Biophysical Journal, 92(1), 257-266. CELL PRESS
Determination of pK(a) values of titrating residues in proteins provides a direct means of studying electrostatic coupling as well as pH-dependent stability. The B1 domain of protein G provides an excellent model system for such investigations. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e76fe775f1613cb62f429146bcb88a1
Autor:
Erika Gustafsson, Cecilia Forsberg, Lill Ljung, Christina Furebring, Stina Lindman, Karin Haraldsson
Publikováno v:
Protein expression and purification. 63(2)
The Chemotaxis Inhibitory Protein of Staphylococcus aureus (CHIPS) binds and blocks the C5a receptor (C5aR) and formyl-peptide receptor (FPR). This way, CHIPS is a potent inhibitor of the immune cell recruitment associated with inflammation. Truncati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f332bc796cd75ed470a8cd4d354490b1
https://pubmed.ncbi.nlm.nih.gov/18950716
https://pubmed.ncbi.nlm.nih.gov/18950716