Multiplexed Assays of Variant Effect and Automated Patch Clamping Improve KCNH2 -LQTS Variant Classification and Cardiac Event Risk Stratification.

Autor: O'Neill MJ; Medical Scientist Training Program, Vanderbilt University School of Medicine, Nashville, TN (M.J.O., X.B.)., Ng CA; Mark Cowley Lidwill Research Program in Cardiac Electrophysiology, Victor Chang Cardiac Research Institute, Darlinghurst, Australia (C.-A.N., Q.S., C.-Y.T., J.I.V.)., Aizawa T; Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Japan (T.A., A.K.)., Sala L; IRCCS, Istituto Auxologico Italiano, Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, Milan, Italy (L.S., L.C., F.D., G.M., C.S., P.J.S.).; Department of Biotechnology and Biosciences, (L.S.), University of Milano-Bicocca, Milan, Italy., Bains S; Department of Molecular Pharmacology & Experimental Therapeutics (Windland Smith Rice Sudden Death Genomics Laboratory), Mayo Clinic, Rochester, MN (S.B., R.N., J.M.B., J.R.G., M.J.A.)., Winbo A; Department of Physiology (A.W., B.M.K.), University of Auckland, New Zealand., Ullah R; Vanderbilt Center for Arrhythmia Research and Therapeutics, Division of Clinical Pharmacology (R.U., K.K., L.R.V., D.W.M., A.S., Y.W., L.C., M.C.L., A.M.G., B.C.K., D.M.R.), Department of Medicine, Vanderbilt University Medical Center, Nashville, TN., Shen Q; Mark Cowley Lidwill Research Program in Cardiac Electrophysiology, Victor Chang Cardiac Research Institute, Darlinghurst, Australia (C.-A.N., Q.S., C.-Y.T., J.I.V.)., Tan CY; School of Clinical Medicine, University of New South Wales Sydney, Darlinghurst, New South Wales, Australia (C.-A.N., J.I.V.)., Kozek K; Vanderbilt Center for Arrhythmia Research and Therapeutics, Division of Clinical Pharmacology (R.U., K.K., L.R.V., D.W.M., A.S., Y.W., L.C., M.C.L., A.M.G., B.C.K., D.M.R.), Department of Medicine, Vanderbilt University Medical Center, Nashville, TN., Vanags LR; Vanderbilt Center for Arrhythmia Research and Therapeutics, Division of Clinical Pharmacology (R.U., K.K., L.R.V., D.W.M., A.S., Y.W., L.C., M.C.L., A.M.G., B.C.K., D.M.R.), Department of Medicine, Vanderbilt University Medical Center, Nashville, TN., Mitchell DW; Vanderbilt Center for Arrhythmia Research and Therapeutics, Division of Clinical Pharmacology (R.U., K.K., L.R.V., D.W.M., A.S., Y.W., L.C., M.C.L., A.M.G., B.C.K., D.M.R.), Department of Medicine, Vanderbilt University Medical Center, Nashville, TN., Shen A; Vanderbilt Center for Arrhythmia Research and Therapeutics, Division of Clinical Pharmacology (R.U., K.K., L.R.V., D.W.M., A.S., Y.W., L.C., M.C.L., A.M.G., B.C.K., D.M.R.), Department of Medicine, Vanderbilt University Medical Center, Nashville, TN., Wada Y; Vanderbilt Center for Arrhythmia Research and Therapeutics, Division of Clinical Pharmacology (R.U., K.K., L.R.V., D.W.M., A.S., Y.W., L.C., M.C.L., A.M.G., B.C.K., D.M.R.), Department of Medicine, Vanderbilt University Medical Center, Nashville, TN., Kashiwa A; Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Japan (T.A., A.K.)., Crotti L; IRCCS, Istituto Auxologico Italiano, Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, Milan, Italy (L.S., L.C., F.D., G.M., C.S., P.J.S.).; Department of Medicine and Surgery (L.C.), University of Milano-Bicocca, Milan, Italy., Dagradi F; IRCCS, Istituto Auxologico Italiano, Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, Milan, Italy (L.S., L.C., F.D., G.M., C.S., P.J.S.)., Musu G; IRCCS, Istituto Auxologico Italiano, Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, Milan, Italy (L.S., L.C., F.D., G.M., C.S., P.J.S.)., Spazzolini C; IRCCS, Istituto Auxologico Italiano, Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, Milan, Italy (L.S., L.C., F.D., G.M., C.S., P.J.S.)., Neves R; Department of Molecular Pharmacology & Experimental Therapeutics (Windland Smith Rice Sudden Death Genomics Laboratory), Mayo Clinic, Rochester, MN (S.B., R.N., J.M.B., J.R.G., M.J.A.)., Bos JM; Department of Molecular Pharmacology & Experimental Therapeutics (Windland Smith Rice Sudden Death Genomics Laboratory), Mayo Clinic, Rochester, MN (S.B., R.N., J.M.B., J.R.G., M.J.A.)., Giudicessi JR; Department of Molecular Pharmacology & Experimental Therapeutics (Windland Smith Rice Sudden Death Genomics Laboratory), Mayo Clinic, Rochester, MN (S.B., R.N., J.M.B., J.R.G., M.J.A.)., Bledsoe X; Medical Scientist Training Program, Vanderbilt University School of Medicine, Nashville, TN (M.J.O., X.B.)., Gamazon ER; Division of Genetic Medicine (E.R.G.), Department of Medicine, Vanderbilt University Medical Center, Nashville, TN., Lancaster MC; Vanderbilt Center for Arrhythmia Research and Therapeutics, Division of Clinical Pharmacology (R.U., K.K., L.R.V., D.W.M., A.S., Y.W., L.C., M.C.L., A.M.G., B.C.K., D.M.R.), Department of Medicine, Vanderbilt University Medical Center, Nashville, TN., Glazer AM; Vanderbilt Center for Arrhythmia Research and Therapeutics, Division of Clinical Pharmacology (R.U., K.K., L.R.V., D.W.M., A.S., Y.W., L.C., M.C.L., A.M.G., B.C.K., D.M.R.), Department of Medicine, Vanderbilt University Medical Center, Nashville, TN., Knollmann BC; Vanderbilt Center for Arrhythmia Research and Therapeutics, Division of Clinical Pharmacology (R.U., K.K., L.R.V., D.W.M., A.S., Y.W., L.C., M.C.L., A.M.G., B.C.K., D.M.R.), Department of Medicine, Vanderbilt University Medical Center, Nashville, TN., Roden DM; Vanderbilt Center for Arrhythmia Research and Therapeutics, Division of Clinical Pharmacology (R.U., K.K., L.R.V., D.W.M., A.S., Y.W., L.C., M.C.L., A.M.G., B.C.K., D.M.R.), Department of Medicine, Vanderbilt University Medical Center, Nashville, TN., Weile J; Department of Medicine and Surgery, University Milano Bicocca, Milan, Italy. Department of Molecular Genetics, University of Toronto, Canada (J.W., F.R.)., Roth F; Department of Medicine and Surgery, University Milano Bicocca, Milan, Italy. Department of Molecular Genetics, University of Toronto, Canada (J.W., F.R.)., Salem JE; Sorbonne University, APHP, INSERM, Clinical Pharmacology, Hopital Pitié-Salpétière Department of Medicine (J.-E.S.), University of Auckland, New Zealand., Earle N; Department of Cardiology, Waikato Hospital, Hamilton, New Zealand (N.E., R.S.)., Stiles R; Department of Cardiology, Waikato Hospital, Hamilton, New Zealand (N.E., R.S.)., Agee T; Department of Chemistry, Mississippi State University, Starkville (T.A., C.N.J.)., Johnson CN; Department of Chemistry, Mississippi State University, Starkville (T.A., C.N.J.)., Horie M; Department of Cardiovascular Medicine, Shiga University of Medical Science, Japan (M.H.)., Skinner JR; Sydney Children's Hospital Network, University of Sydney, Australia (J.R.S.)., Ackerman MJ; Department of Molecular Pharmacology & Experimental Therapeutics (Windland Smith Rice Sudden Death Genomics Laboratory), Mayo Clinic, Rochester, MN (S.B., R.N., J.M.B., J.R.G., M.J.A.)., Schwartz PJ; IRCCS, Istituto Auxologico Italiano, Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, Milan, Italy (L.S., L.C., F.D., G.M., C.S., P.J.S.)., Ohno S; Department of Bioscience and Genetics, National Cerebral and Cardiovascular Center, Osaka, Japan (S.O.)., Vandenberg JI; Mark Cowley Lidwill Research Program in Cardiac Electrophysiology, Victor Chang Cardiac Research Institute, Darlinghurst, Australia (C.-A.N., Q.S., C.-Y.T., J.I.V.)., Kroncke BM; Department of Physiology (A.W., B.M.K.), University of Auckland, New Zealand.

Publikováno v: Circulation [Circulation] 2024 Dec 03; Vol. 150 (23), pp. 1869-1881. Date of Electronic Publication: 2024 Sep 24.

Genetic Testing Yield and Clinical Characteristics of Hypertrophic Cardiomyopathy in Understudied Ethnic Groups: Insights From a New Zealand National Registry.

Autor: Earle NJ; Departments of Medicine (N.J.E.), University of Auckland, New Zealand.; Greenlane Paediatric and Congenital Cardiac Services, Starship Children's Hospital, Auckland, New Zealand (N.J.E., J.C., L.M.)., Winbo A; Physiology (A.W.), University of Auckland, New Zealand., Crawford J; Greenlane Paediatric and Congenital Cardiac Services, Starship Children's Hospital, Auckland, New Zealand (N.J.E., J.C., L.M.)., Wheeler M; Department of Cardiology, Auckland City Hospital, New Zealand (M.W., A.M.)., Stiles R; Department of Cardiology, Waikato Hospital, Hamilton, New Zealand (R.S., M.K.S.)., Donoghue T; Department of Cardiology, Wellington Hospital, New Zealand (T.D.)., Stiles MK; Department of Cardiology, Waikato Hospital, Hamilton, New Zealand (R.S., M.K.S.)., Hayes I; Genetic Health Service New Zealand, Northern Hub, Auckland (I.H.)., Marcondes L; Greenlane Paediatric and Congenital Cardiac Services, Starship Children's Hospital, Auckland, New Zealand (N.J.E., J.C., L.M.)., Martin A; Department of Cardiology, Auckland City Hospital, New Zealand (M.W., A.M.)., Skinner JR; Heart Centre for Children, Children's Hospital at Westmead, Sydney Children's Hospital Network, NSW, Australia (J.R.S.).; Department of Paediatric and Adolescent Medicine, University of Sydney, NSW, Australia (J.R.S.).

Publikováno v: Circulation. Heart failure [Circ Heart Fail] 2024 Mar; Vol. 17 (3), pp. e010970. Date of Electronic Publication: 2024 Mar 08.

Disseminating early interventions for disaster mental health response using the ECHO model.

Autor: Hambrick EP; Department of Psychology, University of Missouri-Kansas City, Kansas City, Missouri, USA., Williams JL; Department of Psychology, University of Missouri-Kansas City, Kansas City, Missouri, USA., Hardt MM; Department of Psychology, University of Missouri-Kansas City, Kansas City, Missouri, USA., Collins JO; Department of Psychology, University of Missouri-Kansas City, Kansas City, Missouri, USA., Punt SE; Department of Pediatrics, University of Kansas Medical Center, Kansas City, Kansas, USA., Rincon Caicedo M; Department of Psychology, University of Kansas, Lawrence, Kansas, USA., Zhang EA; Department of Occupational Therapy Education, University of Kansas Medical Center, Kansas City, Kansas, USA., Maras M; Department of Pediatrics, University of Kansas Medical Center, Kansas City, Kansas, USA., Lopez Mader L; Department of Psychology, University of Missouri-Kansas City, Kansas City, Missouri, USA., Stiles R; Department of Pediatrics, University of Kansas Medical Center, Kansas City, Kansas, USA., Nelson EL; Department of Pediatrics, University of Kansas Medical Center, Kansas City, Kansas, USA.

Publikováno v: Journal of community psychology [J Community Psychol] 2023 Jul; Vol. 51 (5), pp. 2213-2228. Date of Electronic Publication: 2023 Mar 04.

Brugada Syndrome in New Zealand: The Experience of the National Cardiac Inherited Disease Group

Autor: Gelbart, D., Earle, N., Stiles, R., Donohughe, T., Winbo, A., Marcondes, L., Martin, A., Stiles, M., Skinner, J.

Publikováno v: In Heart, Lung and Circulation 2022 31 Supplement 1:S7-S7

Significance of the Carriage of Sarcomeric Mutations in Hypertrophic Cardiomyopathy in New Zealand

Autor: Earle, N., Winbo, A., Crawford, J., Wheeler, M., Stiles, R., Donoghue, T., Stiles, M., Hayes, I., Marcondes, L., Martin, A., Skinner, J.

Publikováno v: In Heart, Lung and Circulation 2021 30 Supplement 2:S61-S61