A System-wide Approach to Monitor Responses to Synergistic BRAF and EGFR Inhibition in Colorectal Cancer Cells

Autor: Lodewyk F. A. Wessels, René Bernards, Lisanne de la Fonteijne, Sara Mainardi, Gianluca Maddalo, Edwin Cuppen, Albert J. R. Heck, Anna Ressa, Myrthe Jager, A. F. Maarten Altelaar, Joep de Ligt, Martin Fitzpatrick, Anirudh Prahallad, Stijn Groten, Evert Bosdriesz

Publikováno v: Ressa, A, Bosdriesz, E, de Ligt, J, Mainardi, S, Maddalo, G, Prahallad, A, Jager, M, de la Fonteijne, L, Fitzpatrick, M, Groten, S, Altelaar, A F M, Bernards, R, Cuppen, E, Wessels, L & Heck, A J R 2018, ' A System-wide Approach to Monitor Responses to Synergistic BRAF and EGFR Inhibition in Colorectal Cancer Cells ', Molecular and Cellular Proteomics, vol. 17, no. 10, pp. 1892-1908 . https://doi.org/10.1074/mcp.RA117.000486
Molecular and Cellular Proteomics, 17(10), 1892-1908. American Society for Biochemistry and Molecular Biology Inc.
Molecular & Cellular Proteomics, 17(10), 1892. American Society for Biochemistry and Molecular Biology Inc.

Intrinsic and/or acquired resistance represents one of the great challenges in targeted cancer therapy. A deeper understanding of the molecular biology of cancer has resulted in more efficient strategies, where one or multiple drugs are adopted in no

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https://dspace.library.uu.nl/handle/1874/377105