Zobrazeno 1 - 10
of 463
pro vyhledávání: '"Stijn E Verleden"'
Autor:
R. Patrick Xian, Claire L. Walsh, Stijn E. Verleden, Willi L. Wagner, Alexandre Bellier, Sebastian Marussi, Maximilian Ackermann, Danny D. Jonigk, Joseph Jacob, Peter D. Lee, Paul Tafforeau
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-10 (2022)
Measurement(s) Human left lung Technology Type(s) X-Ray Phase-Contrast Imaging
Externí odkaz:
https://doaj.org/article/2471418d6dc94d60b99ee7984241f0e5
Autor:
Gizem Günes Günsel, Thomas M. Conlon, Aicha Jeridi, Rinho Kim, Zeynep Ertüz, Niklas J. Lang, Meshal Ansari, Mariia Novikova, Dongsheng Jiang, Maximilian Strunz, Mariia Gaianova, Christine Hollauer, Christina Gabriel, Ilias Angelidis, Sebastian Doll, Jeanine C. Pestoni, Stephanie L. Edelmann, Marlene Sophia Kohlhepp, Adrien Guillot, Kevin Bassler, Hannelore P. Van Eeckhoutte, Özgecan Kayalar, Nur Konyalilar, Tamara Kanashova, Sophie Rodius, Carolina Ballester-López, Carlos M. Genes Robles, Natalia Smirnova, Markus Rehberg, Charu Agarwal, Ioanna Krikki, Benoit Piavaux, Stijn E. Verleden, Bart Vanaudenaerde, Melanie Königshoff, Gunnar Dittmar, Ken R. Bracke, Joachim L. Schultze, Henrik Watz, Oliver Eickelberg, Tobias Stoeger, Gerald Burgstaller, Frank Tacke, Vigo Heissmeyer, Yuval Rinkevich, Hasan Bayram, Herbert B. Schiller, Marcus Conrad, Robert Schneider, Ali Önder Yildirim
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Chronic obstructive pulmonary disease is a progressive and incurable chronic condition that involves accumulation of inflammatory macrophages in the lung tissue. Authors here show in mouse models of lung disease that PRMT7, a protein arginine methylt
Externí odkaz:
https://doaj.org/article/a84378847bdf46488a490ed2e06676b9
Autor:
Maximilian Ackermann, Jan C. Kamp, Christopher Werlein, Claire L. Walsh, Helge Stark, Verena Prade, Rambabu Surabattula, Willi L. Wagner, Catherine Disney, Andrew J. Bodey, Thomas Illig, Diana J. Leeming, Morten A. Karsdal, Alexandar Tzankov, Peter Boor, Mark P. Kühnel, Florian P. Länger, Stijn E. Verleden, Hans M. Kvasnicka, Hans H. Kreipe, Axel Haverich, Stephen M. Black, Axel Walch, Paul Tafforeau, Peter D. Lee, Marius M. Hoeper, Tobias Welte, Benjamin Seeliger, Sascha David, Detlef Schuppan, Steven J. Mentzer, Danny D. Jonigk
Publikováno v:
EBioMedicine, Vol 85, Iss , Pp 104296- (2022)
Summary: Background: COVID-19 is characterized by a heterogeneous clinical presentation, ranging from mild symptoms to severe courses of disease. 9–20% of hospitalized patients with severe lung disease die from COVID-19 and a substantial number of
Externí odkaz:
https://doaj.org/article/b4f5f451eaf04dc4b18d8490c6c059a3
Autor:
Anna Elisabeth Frick, Michaela Orlitová, Arno Vanstapel, Sofie Ordies, Sandra Claes, Dominique Schols, Tobias Heigl, Janne Kaes, Berta Saez-Gimenez, Robin Vos, Geert M. Verleden, Bart Vanaudenaerde, Stijn E. Verleden, Dirk E. Van Raemdonck, Arne P. Neyrinck
Publikováno v:
Intensive Care Medicine Experimental, Vol 9, Iss 1, Pp 1-15 (2021)
Abstract Background Primary graft dysfunction (PGD) remains a major obstacle after lung transplantation. Ischemia–reperfusion injury is a known contributor to the development of PGD following lung transplantation. We developed a novel approach to a
Externí odkaz:
https://doaj.org/article/61ba9a7e658b4ca3b6b58792f683221d
Autor:
Stijn E. Verleden, Peter Braubach, Christopher Werlein, Edith Plucinski, Mark P. Kuhnel, Annemiek Snoeckx, Haroun El Addouli, Tobias Welte, Axel Haverich, Florian P. Laenger, Sabine Dettmer, Patrick Pauwels, Veronique Verplancke, Paul E. Van Schil, Therese Lapperre, Johanna M. Kwakkel-Van-Erp, Maximilian Ackermann, Jeroen M. H. Hendriks, Danny Jonigk
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Pathology and radiology are complimentary tools, and their joint application is often crucial in obtaining an accurate diagnosis in non-neoplastic pulmonary diseases. However, both come with significant limitations of their own: Computed Tomography (
Externí odkaz:
https://doaj.org/article/9d7fd2cd5ac24be39671d93b5803590a
Autor:
Gisli G. Einarsson, Bart M. Vanaudenaerde, Christopher D. Spence, Andrew J. Lee, Mieke Boon, Geert M. Verleden, J. Stuart Elborn, Lieven J. Dupont, Dirk Van Raemdonck, Deirdre F. Gilpin, Robin Vos, Stijn E. Verleden, Michael M. Tunney
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2022)
To date, investigations of the microbiota in the lungs of people with Cystic Fibrosis (PWCF) have primarily focused on microbial community composition in luminal mucus, with fewer studies observing the microbiota in tissue samples from explanted lung
Externí odkaz:
https://doaj.org/article/e3be9f4b85574b029f366d976f295448
Autor:
Carolina Ballester-López, Thomas M. Conlon, Zeynep Ertüz, Flavia R. Greiffo, Martin Irmler, Stijn E. Verleden, Johannes Beckers, Isis E. Fernandez, Oliver Eickelberg, Ali Önder Yildirim
Publikováno v:
EBioMedicine, Vol 43, Iss , Pp 562-575 (2019)
Background: Chronic Obstructive Pulmonary Disease (COPD) is the third leading cause of death worldwide with no curative therapy. A non-canonical Notch ligand, DNER, has been recently identified in GWAS to associate with COPD severity, but its functio
Externí odkaz:
https://doaj.org/article/17de654a891c42d38950f3b88bf49d6f
Autor:
Arno Vanstapel, Roel Goldschmeding, Roel Broekhuizen, Tri Nguyen, Annelore Sacreas, Janne Kaes, Tobias Heigl, Stijn E. Verleden, Alexandra De Zutter, Geert Verleden, Birgit Weynand, Erik Verbeken, Laurens J. Ceulemans, Dirk E. Van Raemdonck, Arne P. Neyrinck, Helene M. Schoemans, Bart M. Vanaudenaerde, Robin Vos
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundConnective tissue growth factor (CTGF) is an important mediator in several fibrotic diseases, including lung fibrosis. We investigated CTGF-expression in chronic lung allograft dysfunction (CLAD) and pulmonary graft-versus-host disease (GVH
Externí odkaz:
https://doaj.org/article/9937a8aff2ce416b9faf055ca2881abd
Autor:
Feng Xu, Naoya Tanabe, Dragos M. Vasilescu, John E. McDonough, Harvey O. Coxson, Kohei Ikezoe, Daisuke Kinose, Kevin W. Ng, Stijn E. Verleden, Wim A. Wuyts, Bart M. Vanaudenaerde, Johny Verschakelen, Joel D. Cooper, Marc E. Lenburg, Katrina B. Morshead, Alexander R. Abbas, Joseph R. Arron, Avrum Spira, Tillie-Louise Hackett, Thomas V. Colby, Christopher J. Ryerson, Raymond T. Ng, James C. Hogg
Publikováno v:
EBioMedicine, Vol 66, Iss , Pp 103325- (2021)
Background: The transition from normal lung anatomy to minimal and established fibrosis is an important feature of the pathology of idiopathic pulmonary fibrosis (IPF). The purpose of this report is to examine the molecular and cellular mechanisms as
Externí odkaz:
https://doaj.org/article/26f5a885d9724d8aa67297d80c625a69
Canonical WNT pathway is activated in the airway epithelium in chronic obstructive pulmonary disease
Autor:
François M. Carlier, Sébastien Dupasquier, Jérôme Ambroise, Bruno Detry, Marylène Lecocq, Charline Biétry–Claudet, Yassine Boukala, Jean-Luc Gala, Caroline Bouzin, Stijn E. Verleden, Delphine Hoton, Sophie Gohy, Bertrand Bearzatto, Charles Pilette
Publikováno v:
EBioMedicine, Vol 61, Iss , Pp 103034- (2020)
Background: Chronic obstructive pulmonary disease (COPD) is a devastating lung disease, mainly due to cigarette smoking, which represents the third cause of mortality worldwide. The mechanisms driving its epithelial salient features remain largely el
Externí odkaz:
https://doaj.org/article/d7ae69faa43748118a5acdea35ec9710